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youngjunpark.bsky.social

@youngjunpark.bsky.social

Reposted by @youngjunpark.bsky.social

Joost Snijder @joostsnijder.bsky.social · 30/03/2026

Structure of SARS-CoV-2 spike in complex with its co-receptor the neuronal cell adhesion protein contactin1 www.biorxiv.org/content/10.6... Check out our new preprint. Cool structure by Sabrina Krepel with Bert Janssen. Thanks to @danielhurdiss.bsky.social @utrechtvirology.bsky.social #covid #pais

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Reposted by @youngjunpark.bsky.social

Veesler lab @veeslerlab.bsky.social · 28/04/2026

How are host proteases promoting coronavirus entry into cells? Find out by reading our latest manuscript led by @mattmccallum.bsky.social Brett Case Jack Brown & @youngjunpark.bsky.social in collaboration with @msdiamondlab.bsky.social 1/19 www.nature.com/articles/s41...

nature.com

TMPRSS2-mediated coronavirus spike activation and inhibition - Nature Structural & Molecular Biology

Here, the authors elucidate TMPRSS2 protease recognition of the SARS-CoV-2 spike S2′ cleavage site, revealing the molecular basis of activation of membrane fusion, and show that antibodies recognizing...

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Reposted by @youngjunpark.bsky.social

Veesler lab @veeslerlab.bsky.social · 21/02/2025

We show that the HKU25 clade of merbecoviruses utilizes the ACE2 receptor with a binding mode sharing similarity to HKU5, suggesting a common evolutionary origin of ACE2 utilization. Led by Young-Jun Park on our side. Collab with Huan Yan's lab! @hhmi.bsky.social www.biorxiv.org/content/10.1...

biorxiv.org

ACE2 utilization of HKU25 clade MERS-related coronaviruses with broad geographic distribution

Dipeptidyl peptidase-4 (DPP4) is a well-established receptor for several MERS-related coronaviruses (MERSr-CoVs) isolated from humans, camels, pangolins, and bats. However, the receptor usage of many ...

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