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Vizgen

@vizgen.bsky.social
350 followers 10 following 97 posts

Confidently take your research to new depths with MERSCOPE Ultra integrating single-cell and spatial multiomics analysis powered by MERFISH technology.

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Vizgen @vizgen.bsky.social · 07/04/2026
We’re excited to be at #AACR2026 next week in ☀️San Diego ! Stop by booth #1655 for a live demo of the MERSCOPE Ultra™ Platform and get a preview of what’s coming next in our product roadmap. Looking forward to discussing how #SpatialGenomics is advancing #CancerResearch.
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Filipa Simões @simoesfilipa.bsky.social · 23/03/2026
Excited to share our #preprint showing that #macrophages in the regenerating #zebrafish #heart are shaped by local cardiac-immune microniches, with a fibroblast-to-macrophage signal promoting regeneration over fibrotic repair www.biorxiv.org/content/10.6... @idrm.ox.ac.uk @oxforddpag.bsky.social
biorxiv.org
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Filipa Simões @simoesfilipa.bsky.social · 23/03/2026
Huge thanks to everyone involved - with a massive shout-out to @ehsanrazaghi.bsky.social & @selintuzuner.bsky.social for driving this work while doing their MSc projects in the lab, to our collaborator @beckrichardson.bsky.social and @thebhf.bsky.social for supporting curiosity-driven research🫀
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Filipa Simões @simoesfilipa.bsky.social · 24/03/2026
@vizgen.bsky.social #MERFISH
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Vizgen @vizgen.bsky.social · 23/03/2026
We’ve updated the Vizgen Customer Portal to make it easier than ever to find what you need. From curated resources to integrated training videos and simplified search, everything is designed to help keep your experiments moving forward. Plus access the latest data releases! 🔗 portal.vizgen.com
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Vizgen @vizgen.bsky.social · 23/03/2026
We’ve updated the Vizgen Customer Portal to make it easier than ever to find what you need. From curated resources to integrated training videos and simplified search, everything is designed to help keep your experiments moving forward. Plus access the latest data releases! 🔗 portal.vizgen.com
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Vizgen @vizgen.bsky.social · 17/03/2026
Advance your #ADC research with OmniVUE™ panels powered by InSituPlex® chemistry. Enable high-sensitivity multiplex biomarker detection in human tissues- supporting translational research. Customizable panels (30+ biomarkers) deliver precise spatial proteomics data. 🔗 in comments.
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Vizgen @vizgen.bsky.social · 16/03/2026
Pre-designed panels support reproducibility, while enabling deep spatial insights. Using the IO panel, a FFPE colon cancer dataset captured ~150M transcripts across ~700K cells, resolving tumor populations & diverse immune subsets to map the TME. 🔗dataset: info.vizgen.com/merfish-2.0-...
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Vizgen @vizgen.bsky.social · 12/03/2026
New preprint: MERFISH 2.0, an ultra-sensitive spatial transcriptomics chemistry for diverse tissue types. MERFISH 2.0 improves profiling of fragmented RNA across complex samples, enabling up to ~8× higher transcript detection sensitivity & improved cell recovery. Link in comments.
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Vizgen @vizgen.bsky.social · 12/03/2026
New preprint: MERFISH 2.0, an ultra-sensitive spatial transcriptomics chemistry for diverse tissue types. MERFISH 2.0 improves profiling of fragmented RNA across complex samples, enabling up to ~8× higher transcript detection sensitivity & improved cell recovery. Link in comments.
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Vizgen @vizgen.bsky.social · 25/02/2026
This #HeartMonth, we’re highlighting how spatial transcriptomics is advancing cardiac research. MERFISH 2.0™ enables high-plex, single-cell profiling across large cardiac tissue areas, including dense cardiomyocyte regions. Explore our new flyer: vizgen.com/resources/ca...
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Vizgen @vizgen.bsky.social · 13/02/2026
We’re proud to support the spatial and single-cell community at #AGBT26! Vizgen will be in Orlando (Feb 23–26) as a Contributing Sponsor, sharing the latest advances across MERFISH 2.0™, MERSCOPE Ultra™, and integrated transcriptomic + proteomic workflows. See you there!
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Vizgen @vizgen.bsky.social · 27/01/2026
It’s always exciting to see spatial transcriptomics applied beyond traditional biomedical research. Great work from one of our Certified Service Providers, @earlhaminst.bsky.social‬!
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Vizgen @vizgen.bsky.social · 22/01/2026
Explore the new Vizgen website. Discover workflows and tools for spatial transcriptomics, spatial proteomics, and integrated RNA and protein analysis in intact tissue. hubs.ly/Q03_DD9Q0 #SpatialMultiomics
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Vizgen @vizgen.bsky.social · 21/01/2026
Spatial transcriptomics reveals that microglia play more nuanced roles in Alzheimer’s disease. A new @nature.com study identifies a PU.1-low, lymphoid-like microglial state near amyloid plaques, linked to reduced pathology. hubs.ly/Q03-thJp0
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Lymphoid gene expression supports neuroprotective microglia function - Nature
PU.1low CD28-expressing microglia may act as suppressive cells in Alzheimer’s disease, mitigating its progression by reducing neuroinflammation and amyloid plaque load, indicating potential immunother...
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Vizgen @vizgen.bsky.social · 14/01/2026
Great recap from Stanford’s Beckman Center on the recent MERSCOPE User Group Meeting. A nice look at how researchers are applying spatial transcriptomics across brain development, disease, and aging while keeping tissue context intact. hubs.ly/Q03-sXW30 #SpatialBiology
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Vizgen @vizgen.bsky.social · 06/01/2026
MERFISH is helping reveal how immune cells interact with glia in aging white matter. In this webinar clip, the Groh Lab shows MERFISH-detected T cells forming distinct niches enriched for CXCL10, primarily from reactive astrocytes. Full webinar: hubs.ly/Q03Z0mgP0
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Vizgen @vizgen.bsky.social · 29/12/2025
MERFISH is helping reveal how immune cells interact with glia in aging white matter. In this webinar clip, the Groh Lab shows MERFISH-detected T cells forming distinct niches enriched for CXCL10, primarily from reactive astrocytes. Full webinar: hubs.ly/Q03Z0mgP0
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Vizgen @vizgen.bsky.social · 24/12/2025
We’re excited to announce the winners of the Human Cell Atlasing Grant Program! Each winner will receive one free MERSCOPE Ultra™ slide run using a MERFISH 2.0™ gene panel. Congrats to the winners! We can’t wait to follow your progress. #CellAtlas
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Vizgen @vizgen.bsky.social · 17/12/2025
At a time when the world faces immense challenges, science remains a powerful source of hope and progress. Meet Vizgen's Kagimoto-san, who helps bring technologies to scientists, strengthening a global community committed to improving lives through innovation. #BoundByScience
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Vizgen @vizgen.bsky.social · 12/12/2025
What if MS progression is driven by a tiny inflammatory rim at the lesion edge, not diffuse inflammation? A new Immunity study used MERFISH on Vizgen’s MERSCOPE Platform to map active lesions and uncover this inflammatory niche. t.co/Q1ATxCzyz2 #SpatialBiology
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Vizgen @vizgen.bsky.social · 02/12/2025
At Vizgen, we are incredibly proud of our worldwide team and the mission that binds us together. No matter where we live, we are all bound by science, and united by what it makes possible. Meet Anjana from Melbourne, Australia. #BoundByScience #SpatialGenomics #ScienceforGood
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Vizgen @vizgen.bsky.social · 26/11/2025
Miss our posters at #SITC2025? Now available: Vizgen's poster presentations showing how spatial multi-omics deepens our understanding of the tumor microenvironment w/ MERFISH 2.0™, the MERSCOPE® platform, and InSituPlex® mIF workflows. Download here: info.vizgen.com/sitc-2025-ca...
info.vizgen.com
SITC 2025: Cancer-Immune Study with Vizgen
Learn about investigating cancer and immune cell interactions in the tumor microenvironment with Vizgen's Multi-omics Platforms. Download Vizgen's SITC 2025 posters today!
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Vizgen @vizgen.bsky.social · 21/11/2025
New in @nature.com, researchers combined single-nucleus RNA sequencing, high-resolution #spatialtranscriptomics, and proteomics to map the molecular architecture of mid-gestational prenatal Down syndrome cortex and a trisomic Ts65Dn mouse model. (1/3)
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Vizgen @vizgen.bsky.social · 19/11/2025
Just published in Cell Press: Researchers used MERSCOPE® to show how microglia and astrocytes coordinate synapse remodeling in the intact mouse brain, revealing a spatially orchestrated glial dialogue that fine-tunes neural circuits. hubs.ly/Q03SdHXN0
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Vizgen @vizgen.bsky.social · 12/11/2025
Join us at #SfN25 to explore how high-sensitivity #spatialtranscriptomics is reshaping brain research. Stop by booth 513 and our 2 poster sessions to see how MERFISH 2.0™ and MERSCOPE Ultra™ support deeper, more precise insights into the complexity of the brain.
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Vizgen @vizgen.bsky.social · 07/11/2025
Today at #SITC2025: Get a first look at how MERFISH 2.0™ data generated on MERSCOPE Ultra™ is combined with InSituPlex® multiplex immunofluorescence on sequential sections to decode the tumor–immune microenvironment. 12:15-1:45 p.m. & 5:35-7 p.m. #SpatialBiology #SpatialMultiOmics
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Vizgen @vizgen.bsky.social · 30/10/2025
Choosing a spatial platform isn’t just about the next run. It sets you up for your next few years. See the whole picture and pressure-test your options with our Buyer’s Checklist: hubs.ly/Q03QRXVC0
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Vizgen @vizgen.bsky.social · 29/10/2025
Reminder: Join us 10/30 for the Labroots webinar: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain Updated times: 6 am PDT | 9 am EDT | 2 pm CET | 10 pm SGT Register: www.labroots.com/ms/webinar/m... #SpatialTranscriptomics #Neurobiology #SpatialBiology
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Vizgen @vizgen.bsky.social · 24/10/2025
Spatial biology in 3D. In Genetic Engineering and Biotechnology News, read how combining spatial transcriptomics & multiplex proteomics clarifies tumor–immune signaling & bridges mechanistic insight into clinical readouts. Vizgen’s Manisha Ray weighs in on what’s next for analysis: hubs.ly/Q03PPC210
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Exploring Biology in Three Dimensions
Spatial biology technologies reveal new dimensions for understanding cellular interactions in their native environment.
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Vizgen @vizgen.bsky.social · 21/10/2025
Join us 10/30 for a Labroots webinar with Dr. Janos Groh: From Myelin Damage to Immune Dysfunction: Unravelling the Aging Brain. Hear how single-cell + spatial transcriptomics reveal glial–immune interactions driving neurodegeneration. Register: hubs.ly/Q03N0rVJ0
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From Myelin Damage to Immune Dysfunction: Unraveling the Aging Brain
Aging is associated with progressive white matter degeneration, which impairs brain structure and function. Defects in myelinating glial cells, combined with chronic neuroinflammation, contr
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Vizgen @vizgen.bsky.social · 16/10/2025
Vizgen’s new Cell Atlasing Grant Program is now open. Top 5 tissue types receive one free MERSCOPE Ultra™ slide run using MERFISH 2.0™. Choose custom 960-gene or 815-gene pre-designed panels (IO, Brain, Breast). Apply by 10/24. HCA members only. hubs.ly/Q03NCPPv0
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Vizgen @vizgen.bsky.social · 01/10/2025
MERFISH 2.0™ delivers a substantial increase in sensitivity, enabling detection of up to 10× more transcripts per field of view. Discover how MERFISH 2.0 is transforming spatial biology for researchers like Dr. Bourdenx: hubs.ly/Q03LCNrY0 #SpatialBiology
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Vizgen @vizgen.bsky.social · 26/09/2025
New data release highlights the power of MERSCOPE Ultra to capture high-resolution #spatialtranscriptomics across a 3.0 cm² imaging area: • Mouse embryo tissue (E10, E12, and E14) on same slide • Normal and Alzheimer’s human brain on same slide hubs.ly/Q03KH7VN0
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Vizgen @vizgen.bsky.social · 18/09/2025
Next-gen spatial transcriptomic tools are helping overcome the challenge of degraded & FFPE samples. Vizgen co-founder Jiang He explains how these advances are opening new doors for research in oncology, neuroscience & beyond: www.biocompare.com/Editorial-Ar...
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Vizgen @vizgen.bsky.social · 16/09/2025
Just published in Nature: U Mass Chan Medical School, a Vizgen Certified Service Provider, mapped the brain’s molecular landscape across the human lifespan using MERSCOPE®, single-cell RNA-seq & genomic data. Read: hubs.ly/Q03JsW0z0 #SpatialBiology #Neuroscience #AgingResearch
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Vizgen @vizgen.bsky.social · 09/09/2025
From discovery to clinical research, #SpatialBiology is shaping precision medicine. With Vizgen, researchers now access: ➡️MERFISH 2.0™ spatial transcriptomics ➡️InSituPlex® multiplex protein analysis ➡️STARVUE™ AI image analysis Explore our tech: hubs.ly/Q03GPSL70
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Vizgen @vizgen.bsky.social · 03/09/2025
How do disseminated tumor cells reveal themselves in the bone marrow? Using MERFISH 2.0™, Mark Watson, Ph.D.'s team can map 200K–500K cells from bone marrow aspirates and distinguish DTCs from other populations w/ a 140-gene panel. Full webinar: hubs.ly/Q03GgGLm0
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Vizgen @vizgen.bsky.social · 26/08/2025
New in @science.org: Researchers paired PEtracer with Vizgen’s MERSCOPE® to map how tumors evolve in vivo—showing how cell ancestry and local microenvironments shape growth and revealing new insights into tumor biology. 🔗 www.science.org/doi/10.1126/...
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Vizgen @vizgen.bsky.social · 25/08/2025
MERFISH 2.0™ enables in situ spatial transcriptomic imaging in fixed frozen mouse bone marrow. ✨ At SR-TIGET, researchers quantified millions of transcripts— unlocking new insights into how cells interact in health and disease. Explore MERFISH 2.0: vizgen.com/technology/#... #SpatialBiology
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Vizgen @vizgen.bsky.social · 13/08/2025
In @cp-cellreports.bsky.social: Researchers used MERSCOPE to help uncover how basophils activate fibroblasts to drive persistent skin inflammation, offering clues for potential new treatments for conditions like atopic dermatitis. www.cell.com/cell-reports...
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Vizgen @vizgen.bsky.social · 06/08/2025
Congrats to the winners of the 2025 Heidelberg MERFISH 2.0™ Grant Program! 🎉 In partnership with scOpenLab, we’re supporting cutting-edge spatial transcriptomics projects using MERFISH 2.0 and predesigned gene panels. We can’t wait to see how these projects progress!
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Vizgen @vizgen.bsky.social · 01/08/2025
Just launched: Vizgen’s Summer of Spatial Technology Evaluation Program! Test industry-leading spatial transcriptomics & proteomics workflows on your own samples with expert support & exclusive pricing. Limited to 10 projects—ends 9/22. Learn more: info.vizgen.com/form-summer-...
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Vizgen @vizgen.bsky.social · 28/07/2025
In Nature: Engineered macrophages eliminated liver metastases in mice by restoring CD8⁺ T-cell activity and reprogramming the tumor microenvironment. MERSCOPE® spatially mapped co-localized immune signals, revealing T-cell rejuvenation in the TME. www.nature.com/articles/s41... #Immunotherapy
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Vizgen @vizgen.bsky.social · 21/07/2025
What makes spatial transcriptomics different? • Single-cell resolution in spatial context • Preserves tissue structure • Reveals insights beyond traditional methods Explore the basics: vizgen.com/what-is-spat...
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Vizgen @vizgen.bsky.social · 17/07/2025
New in Cell: CXCL12 identified as a key genetic driver of coronary artery anatomy. GWAS + spatial transcriptomics using MERSCOPE reveal how gene expression shapes heart development: www.cell.com/cell/fulltex...
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Vizgen @vizgen.bsky.social · 15/07/2025
Now in Singapore: MERSCOPE Ultra™! We're thrilled to announce the first MERSCOPE Ultra install in Southeast Asia at LifeStrands Genomics, in partnership w/ Genomax Technologies. Explore MERFISH 2.0 services now available to researchers across the region: spatial.lifestrandsgx.com/vizgen-mersc...
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Vizgen @vizgen.bsky.social · 07/07/2025
Struggling with cell segmentation in complex tissues like multinucleated muscle or abnormally shaped cells? Enhance your cell segmentation with Vizgen's Cellpose2 Plugin! Learn more about VPT and the plugin: vizgen.com/vpt/ #SpatialBiology
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Vizgen @vizgen.bsky.social · 01/07/2025
More tissue. More speed. More power. MERSCOPE Ultra™ brings 3X imaging area, 1.8X faster run time, and MERFISH 2.0 chemistry, all with sub-cellular resolution and FFPE compatibility. See how spatial genomics scales: vizgen.com/merscope-ult... #SpatialGenomics
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Vizgen @vizgen.bsky.social · 24/06/2025
Uncovering how cells organize into functional niches is a major challenge in spatial biology. A new study in Nature Genetics combines deep learning w/spatial transcriptomics from MERSCOPE® to map tissue architecture and cell communication across millions of cells. www.nature.com/articles/s41...
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