Czernilofsky et al. identified factors that reprogram stromal cells into an inflammatory, dysfunctional state, leading to the structural disorganization of lymph nodes in B cell lymphoma at single-cel...

The global trend toward an increasing aged population demographic raises significant societal challenges, particularly concerning health. As organisms age, progressive tissue dysfunction increases the...

A new version of nanorate DNA sequencing, with an error rate lower than five errors per billion base pairs and compatible with whole-exome and targeted capture, enables epidemiological-scale studies of somatic mutation and selection and the generation of high-resolution selection maps across coding and non-coding sites for many genes.

Men-led papers receive more media coverage than women’s, new study finds

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

Ein interdisziplinäres Team aus Wissenschaftlerinnen und Wissenschaftlern vom Berlin Institute of Health in der Charité (BIH), vom Max Delbrück Center, dem Deutschen Krebsforschungszentrum (DKFZ), dem...

Analysis of physically interacting cells (PICs) in flow cytometry data using R - agSHaas/PICtR

Interact-omics, a high-throughput cytometry-based framework, resolves the cellular interaction landscape.

Adjusting the timing of stem cell infusion can reduce the incidence and severity of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. The rhythmic fluctuations in inflammation levels before infusion dictate subsequent T cell responses, which may be a key factor underlying outcomes based on the time of day that transplantation occurs.

More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.

We’re thrilled to announce the launch of openRxiv as an independent nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences. openRxiv ensures that r...

Europe PMC is an archive of life sciences journal literature.

When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers from Berlin and Heidelberg report in “Sci...

Residing at the top of the hematopoietic hierarchy, long-term hematopoietic stem cells (HSCs) are capable of self-renewal and sustained blood cell regeneration. Over the past decades, single-cell and ...