Reposted by Luka VelasevicEMBL @embl.org · 01/12/2025Nobel laureate Svante Pääbo, Director at the Max Planck Institute for Evolutionary Anthropology in Leipzig, will deliver the 2026 EMBL Kafatos lecture. The lecture will explore how traces of Neanderthal DNA might shape human biology and health today. www.embl.org/news/embl-an... 13811
Reposted by Luka VelasevicEwan Birney @ewanbirney.bsky.social · 14/11/2025Richard so deserves this - a legend in bioinformatics and computational biology - work genome, human genome, Pfam, 1,000 genomes, Sam/bam format, bwa, vcf, psmc… and so many more 48417
Reposted by Luka VelasevicSavitski Lab @savitski-lab.bsky.social · 05/11/2025Happy to see our HT-PELSA paper now published in @natsmb.nature.com 🎊 Big thanks for the constructive review process! 📖Read the manuscript here (www.nature.com/articles/s41...) & check the thread for additional information ⬇️nature.comHigh-throughput peptide-centric local stability assay extends protein–ligand identification to membrane proteins, tissues and bacteria - Nature Structural & Molecular BiologyLi et al. further develop a high-throughput peptide-centric local stability assay that speeds up sample preparation 100-fold and extends protein–ligand identification to membrane proteins, tissues and... 03914
Luka Velasevic @velasevic.bsky.social · 31/10/2025Apparently chimps are better at Bayesian stats than me 010
Reposted by Luka VelasevicMichael Zimmermann Lab @zimmermannlab.bsky.social · 29/10/2025We are very happy to share a new preprint 🎉 Congratulations to everyone involved! @carolinedricot.bsky.social, @denisemselegato.bsky.social, @sarahlebeer.bsky.social and co. www.biorxiv.org/content/10.1...biorxiv.orgVitamin B2 Production by Vaginal Lactobacilli Promotes SymbiosisThe human vaginal microbiome, particularly with lactobacilli as the main inhabitants, plays a key role in maintaining women's health. While lactic acid-mediated pathogen exclusion is well known, broad... 0126
Reposted by Luka VelasevicSvetlana Dodonova @dodonova-sveta.bsky.social · 28/10/2025Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce... 6345118
Reposted by Luka VelasevicTanmay Bharat @tbharat-lab.bsky.social · 31/08/2025Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social www.biorxiv.org/cgi/content/... @mrclmb.bsky.social @wellcometrust.bsky.social 214162
Reposted by Luka VelasevicTypas Lab @typaslab.bsky.social · 13/10/2025Excited to share our preprint led by Carlos Voogdt et al We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera. www.biorxiv.org/content/10.1... 28645
Reposted by Luka VelasevicPopGen Vienna @popgenviennaphd.bsky.social · 02/09/2025The PopGen Vienna Seminar series schedule is ready for the next term (Sep-Jan). It's jam-packed with fantastic speakers in #evolution, #genetics, #genomics, #popgen, and more! Details and streaming link signup can be found on our website popgen-vienna.at/news/seminars/ 01411
Reposted by Luka VelasevicWolfgang Huber @wkhuber.bsky.social · 16/10/2025I regularly get derailed when someone tries to benchmark clustering methods, trying the find the "best" one or the one that agrees with "ground truth". Which clustering of the below animals is the best or the true one? By row, or by column? 108717
Reposted by Luka VelasevicEMBL-EBI @ebi.embl.org · 16/10/2025From magnetic tapes to exabytes of data, Rolf Apweiler has seen it all! As Rolf retires after more than four decades at EMBL, he shares his insights and favourite stories, including how all of EMBL-EBI’s data used to fit in the back of a car. www.ebi.ac.uk/about/news/p... 1215
Reposted by Luka VelasevicMichael Zimmermann Lab @zimmermannlab.bsky.social · 24/09/2025📍Paper alert 📍 Our new preprint is available on: chemrxiv.org/engage/chemr... Here, we show the development of a GC-MS/MS method for the quantification of 120 compounds produced by gut bacteria, including SCFA, indols, organic acids, and amino acid derivatives.chemrxiv.orgDevelopment of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolitesThe gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer.... 0207
Reposted by Luka VelasevicEnard/Hellmann Lab @enardhellmannwg.bsky.social · 04/08/2025Office (4/5): Welcome to the PIs offices We are handling dogs, budgets, people, projects and databases. Ines with Elly is running the dry lab Wolfgang with Mo is running the wet lab It’s such a privilege to work with all these wonderful people ❤️ and we have the best jobs we can imagine. 071
Reposted by Luka VelasevicNature Genetics @natgenet.nature.com · 10/07/2025🎉ONLINE @natgenet.nature.com 📰Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes. By @julianeg.bsky.social, Giulia Cova, Stefan Mundlos and colleagues. ⬇️ www.nature.com/articles/s41...nature.comEnhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature GeneticsActivation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c... 1285