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The Vallee Foundation

@valleefoundation.bsky.social
79 followers 26 following 40 posts

To promote a collegial community of international scientists, to enhance scientific collaboration and communication, and to advance medical education and biomedical research.

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The Vallee Foundation @valleefoundation.bsky.social · 10/03/2026
Congratulations to Vallee Scholar Madeline Lancaster who has won the 2026 Suffrage Science Award which celebrates the scientific achievements of women in science. mrclmb.ac.uk/news-events/...
mrclmb.ac.uk
Madeline Lancaster wins 2026 Suffrage Science Award | MRC Laboratory of Molecular Biology
Madeline Lancaster, Joint Head of the LMB’s Cell Biology Division, has been recognised in the 2026 Suffrage Science Awards.
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The Vallee Foundation @valleefoundation.bsky.social · 10/03/2026
Vallee Scholar Andela Šarić's group will play a central role in a new research project funded by the Austrian Science Fund (FWF) to investigate the biology of the germline, i.e., the cells from which egg cells and sperm cells originate. ista.ac.at/en/news/egg-...
ista.ac.at
Egg Cells & Sperm: New Emerging Fields Project
The Institute of Science and Technology Austria (ISTA) is part of a new research project funded by the Austrian Science Fund (FWF) with 5.1 million Euro as part of the excellent=austria initiative. Ti...
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The Vallee Foundation @valleefoundation.bsky.social · 19/02/2026
Interesting news out of Ricardo Mallarino's (Vallee Scolar 2021) lab: neurosciencenews.com/agouti-gene-...
neurosciencenews.com
Social Competition Can Turn Nurturing Dads into Neglectful Ones - Neuroscience News
A study identifies the Agouti gene as a molecular "off switch" for paternal care in the brain, influenced by environmental social competition.
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The Vallee Foundation @valleefoundation.bsky.social · 03/02/2026
Congratulations to Vallee Scholar Aashish Manglik who has just been named a Vilcek Prize winner: vilcek.org/prizes/prize...
vilcek.org
Aashish Manglik - Vilcek Foundation
Aashish Manglik uncovers the conformational complexity of G protein–coupled receptors, fundamentally reshaping scientists’ understanding of cellular signaling.
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The Vallee Foundation @valleefoundation.bsky.social · 02/12/2025
interesting article from Vallee Scholar Shigeki Watanabe (Johns Hopkins) providing clues to Parkinson's disease: www.sciencedaily.com/releases/202...
sciencedaily.com
New brain imaging breakthrough reveals clues to Parkinson’s
A high-speed “zap-and-freeze” method is giving scientists their clearest view yet of how brain cells send messages. By freezing tissue at the instant a signal fires, researchers revealed how synaptic ...
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The Vallee Foundation @valleefoundation.bsky.social · 01/12/2025
Congratulations to VVP Tony Hyman who is to become the next EMBL Director General nachrichten.idw-online.de/2025/11/27/a...
nachrichten.idw-online.de
Anthony Hyman to become next EMBL Director General
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The Vallee Foundation @valleefoundation.bsky.social · 26/11/2025
Vallee Scholar Shigeki Watanabe and his colleagues at Johns Hopkins Medicine say they have used a “zap-and-freeze” technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans www.hopkinsmedicine.org/news/newsroo...
hopkinsmedicine.org
‘Zap-and-Freeze’ Technique Successfully Used to Watch Human Brain Cell Communication
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The Vallee Foundation @valleefoundation.bsky.social · 25/11/2025
Interesting research that new light on ancient wolves from Vallee Scholar Pontus Skoglund: www.labrujulaverde.com/en/2025/11/u...
labrujulaverde.com
Unusual Discovery of Wolf Remains Thousands of Years Old on a Remote Baltic Island: They Lived with Humans, Shared Their Food, and Could Only Have Arrived by Boat
The relationship between humans and prehistoric canids, a fundamental chapter in the history of our species, has just become significantly more complex. A multidisciplinary team of scientists has anno...
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The Vallee Foundation @valleefoundation.bsky.social · 03/11/2025
And Vallee Scholar Michael Yartsev is discovering how bats learn, remember and form social bonds: www.hhmi.org/news/bat-res...
hhmi.org
How Bat Research Sheds Light on the Brain and Behavior | HHMI
HHMI scientists Michael Yartsev and Gerald Carter are uncovering how bats learn, remember, and form social bonds — findings that could reshape how we understand our own brains and behaviors.
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The Vallee Foundation @valleefoundation.bsky.social · 03/11/2025
Two new papers from Vallee Scholar Johannes Gräff on memory consolidation: www.nature.com/articles/s41... onlinelibrary.wiley.com/doi/epdf/10....
nature.com
Cell-type- and locus-specific epigenetic editing of memory expression - Nature Genetics
CRISPR-based epigenetic editing is used in a cell-type-specific, locus-restricted and temporally controllable manner in the adult mouse brain to modulate memory expression.
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The Vallee Foundation @valleefoundation.bsky.social · 17/10/2025
and from Vallee Scholar Mackenzie Mathis: www.cell.com/cell/fulltex...
cell.com
Decoding the brain: From neural representations to mechanistic models
Understanding how the brain works has been a formidable challenge in neuroscience, but advances at the computational level are now driving us closer. This perspective discusses core concepts of neural...
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The Vallee Foundation @valleefoundation.bsky.social · 17/10/2025
Interesting study from Vallee Scholar Melissa Harrison: medicalxpress.com/news/2025-10...
medicalxpress.com
Fruit fly study reveals genetic targets for rare childhood brain cancer treatment
Using fruit flies, University of Wisconsin–Madison researchers have developed a new model for investigating the genetic drivers of a rare but aggressive brain tumor in children. The work has already i...
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The Vallee Foundation @valleefoundation.bsky.social · 07/10/2025
Vallee Scholar Lisa Giocomo reveals how aging affects special memory news.ssbcrack.com/study-reveal...
news.ssbcrack.com
Study Reveals How Aging Affects Spatial Memory in Mice - SSBCrack News
In a groundbreaking study, researchers at Stanford Medicine have discovered critical insights into how spatial memory declines with aging, revealing potential
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The Vallee Foundation @valleefoundation.bsky.social · 07/10/2025
Vallee Scholar Daniel Jarosz becomes first senior associate dean for basic science at Stanford University. med.stanford.edu/news/all-new...
med.stanford.edu
Dan Jarosz becomes first senior associate dean for basic science
Jarosz is the inaugural appointment to the newly created position, which will support basic science faculty throughout the Stanford School of Medicine.
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The Vallee Foundation @valleefoundation.bsky.social · 07/10/2025
Vallee Scholar Madeline Lancaster appointed Joint Head of the Cell Biology Division at MRC Laboratory of Molecular Biology in Cambridge: www2.mrc-lmb.cam.ac.uk/madeline-lan...
www2.mrc-lmb.cam.ac.uk
Madeline Lancaster appointed Joint Head of the Cell Biology Division - MRC Laboratory of Molecular Biology
Group Leader Madeline Lancaster joins Manu Hegde to oversee the LMB’s Cell Biology Division.
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The Vallee Foundation @valleefoundation.bsky.social · 07/10/2025
Vallee scholar Rickard Sandberg, professor of Molecular Genetics, member of the Nobel Committee, is interviewed by Sharon Jåma about this year's Nobel prize. www.youtube.com/watch?v=5fxn...
youtube.com
“A fundamental discovery about the principle that keeps our immune system in check” | Medicine prize
YouTube video by Nobel Prize
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The Vallee Foundation @valleefoundation.bsky.social · 03/07/2025
Vallee Scholar Weizhe Hong has a new paper out in Nature which shows a remarkable convergence of neuroscience and artificial intelligence: www.eurekalert.org/news-release...
eurekalert.org
First-of-its-kind study finds striking parallels between biological and artificial intelligence during social interaction
A first-of-its-kind study reveals that when mice interact socially, specific brain cell types synchronize in "shared neural spaces," and AI agents develop analogous patterns when engagi...
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The Vallee Foundation @valleefoundation.bsky.social · 19/06/2025
Vallee Scholar Bob Datta is on Instagram with an important message about Alzheimer's research www.instagram.com/reel/DKzuKjR...
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The Vallee Foundation @valleefoundation.bsky.social · 09/06/2025
Congratulations to Vallee Fdtn Director Wade Harper (HMS) on $5M+ Fox Fdtn grant for PD research & collab with VVPs Brenda Schulman, Ulrich Hartl (MPI), Judith Frydman (Stanford) among others in international, multidisciplinary Collaborative Research Network (CRN) hms.harvard.edu/departments/...
hms.harvard.edu
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The Vallee Foundation @valleefoundation.bsky.social · 05/06/2025
Many congratulations to Vallee Scholar Tanmay Bharat, Group Leader in the MRC Lab of Molecular Biology, who has been awarded the EMBO Gold Medal for his research in the field of structural microbiology! www2.mrc-lmb.cam.ac.uk/tanmay-bhara...
www2.mrc-lmb.cam.ac.uk
Tanmay Bharat awarded EMBO Gold Medal - MRC Laboratory of Molecular Biology
Tanmay Bharat, Group Leader in the LMB’s Structural Studies Division, received EMBO’s Gold Medal in recognition of his work on prokaryotic surface molecules.
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The Vallee Foundation @valleefoundation.bsky.social · 28/05/2025
Congratulations to Dr Danelle Devenport (Vallee Scholar 2014), Shirley M. Tilghman Professor of Molecular Biology at Princeton U, who received the President's Award for Distinguished Teaching at Commencement ceremonies on Tuesday, May 27 www.princeton.edu/news/2025/05...
princeton.edu
Faculty members receive President’s Awards for Distinguished Teaching
Professors Rebecca Carey, Gabriel Crouch, Danelle Devenport and Nathaniel Fisch received the President’s Award for Distinguished Teaching at Commencement ceremonies May 27.
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The Vallee Foundation @valleefoundation.bsky.social · 28/05/2025
So happy for our Vallee Visiting Professor Wolfang Baumeister who has just been named the Shaw Prize in Life Science and Medicine: erc.europa.eu/news-events/...
erc.europa.eu
ERC grantee wins the Shaw Prize in Life Science and Medicine
2025 Shaw Prize honours ERC-funded research in molecular imaging
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The Vallee Foundation @valleefoundation.bsky.social · 16/05/2025
Research teams working with Tyler Jacks (VVP 2016) (MIT) and William Freed-Pastor (Dana-Farber and MIT) have a new article in Science in which they show how a class of proteins expressed in pancreatic cancer cells, could serve as targets for immune cell therapy. www.science.org/doi/10.1126/...
science.org
Pancreatic cancer–restricted cryptic antigens are targets for T cell recognition
Translation of the noncoding genome in cancer can generate cryptic (noncanonical) peptides capable of presentation by human leukocyte antigen class I (HLA-I); however, the cancer specificity and immun...
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The Vallee Foundation @valleefoundation.bsky.social · 16/05/2025
Feng Zhang (Vallee Scholar 2013) and his team at the McGovern and Broad Institutes have reengineered a compact RNA-guided enzyme they found in bacteria into an efficient, programmable editor of human DNA. See their paper in Nature Biotch www.nature.com/articles/s41...
nature.com
Evolution-guided protein design of IscB for persistent epigenome editing in vivo - Nature Biotechnology
A combination of engineering approaches is used to improve the function of IscB for a variety of editing activities in vivo.
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The Vallee Foundation @valleefoundation.bsky.social · 16/05/2025
Elena Conti, PhD (Vallee Visiting Prof 2019), Director, MPI of Biochemistry in Martinsried, shares this year’s prestigious Jung Prize for Medicine with Jorn Piel, MD, ETH Zurich. thevalleefoundation.org/news/elena-c...
thevalleefoundation.org
Elena Conti wins Jung Prize for Medicine | The Vallee Foundation
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The Vallee Foundation @valleefoundation.bsky.social · 13/05/2025
Congratulations to Feng Zhang (Vallee Scholar 2013) (Broad Inst, MIT, HHMI Investigator) who received an honorary doctorate from Duke University on Sunday! today.duke.edu/2025/04/duke...
today.duke.edu
Duke to Award Three Honorary Degrees at 2025 Commencement Ceremony | Duke Today
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The Vallee Foundation @valleefoundation.bsky.social · 28/04/2025
Chris Mason (Vallee Scholar 2014) at Weil Cornell Medicine is one of the PIs seeking to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us. news.weill.cornell.edu/news/2025/04...
news.weill.cornell.edu
A VAST New View of Viruses
A major new effort at Weill Cornell Medicine seeks to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us.
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The Vallee Foundation @valleefoundation.bsky.social · 17/04/2025
Vallee Scholar (2021) Ricardo Mallarino (Princeton) has been using the sugar glider (Petaurus breviceps) to investigate immunological defense strategies. Check out his recent paper in Science www.science.org/doi/10.1126/....
science.org
Cathelicidin antimicrobial peptides mediate immune protection in marsupial neonates
Cathelicidin antimicrobial peptides protect marsupial neonates by mediating immune defense against pathogens.
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Reposted by The Vallee Foundation
Dan Landau @landau.bsky.social · 11/04/2025
Excited to share our exploration @naturemethods.bsky.social into new horizons opening up in the era of low cost sequencing! 🔥 Deeper sequencing at WGS scale for PPM sensitivity of tumor informed MRD 🔥Duplex sequencing at WGS scale for plasma only exploration of ctDNA Check out thread 👇
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Reposted by The Vallee Foundation
Pontus Skoglund @pontus-skoglund.bsky.social · 14/04/2025
Join us at the Royal Society in London 14 November for a day on Ancient genomes, human biology and medicine! Many slots are reserved for talks from submitted abstracts related to the topic, alongside speakers Svante Pääbo, Priya Moorjani, @mathiesoniain.bsky.social and Lluis Quintana-Murci.
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Reposted by The Vallee Foundation
Roux Lab, Geneva @rouxlab.bsky.social · 14/04/2025
Abstract submissions for short talks are still opened until April 20th for the EMBO Escrt meeting 2025. There are plenty of options for short talks, please apply online at meetings.embo.org/event/25-escrt
meetings.embo.org
ESCRT function, evolutionary diversity and mechanism of action
The ESCRTs (Endosomal Sorting Complexes Required for Transport) were discovered in 2002 and became one of the most dynamic fields of research in membrane cell biology. ESCRTs are protein complexes fo…
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The Vallee Foundation @valleefoundation.bsky.social · 11/04/2025
Tanmay Bharat (Vallee Scholar 2018) has been working with colleagues at Brandeis University and the Max Planck Institute for Biology, Tubingen, on The Role of Mechanical Forces in Multicellularity:
mpg.de
When the pressure is on, Archaea go multicellular
Mechanical compression induces multicellular organization in archaea
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The Vallee Foundation @valleefoundation.bsky.social · 11/04/2025
New paper from Vallee Scholar (2018) Sichen (Susan) Shao in Science: www.science.org/doi/10.1126/...
science.org
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
ARMC1 partitions between distinct outer mitochondrial membrane complexes and the cytosol to control mitochondrial distribution.
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The Vallee Foundation @valleefoundation.bsky.social · 24/03/2025
Check out Danelle Devenport's latest paper in Science. Danelle, Shirley Tighten Professor of Molecular Biology at Princeton, was a 2014 Vallee Scholar. www.science.org/doi/10.1126/...
science.org
Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...
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The Vallee Foundation @valleefoundation.bsky.social · 21/03/2025
And more from Rickard Sandberg (Vallee Scholar 2015) at the Karolinska www.researchgate.net/publication/...
researchgate.net
Effect of Layer Thickness and Particle Size Distribution on the Microstructure and Properties of Ti6Al4V Processed by Laser Powder Bed Fusion | Request PDF
Request PDF | Effect of Layer Thickness and Particle Size Distribution on the Microstructure and Properties of Ti6Al4V Processed by Laser Powder Bed Fusion | The technological advancements in laser po...
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The Vallee Foundation @valleefoundation.bsky.social · 21/03/2025
New paper from Vallee Scholar Viviana Gradinaru www.nature.com/articles/s41...
nature.com
Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo - Nature Biotechnology
Profiling transcriptional crosstalk between promoters and cell-type-specific enhancers allows large gene cargo delivery.
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Reposted by The Vallee Foundation
Harvard Med Cell Biology @harvardcellbio.bsky.social · 17/03/2025
Exciting new work from the Shao lab @sshaolab.bsky.social by @samanthasedor.bsky.social reveals novel functions and interactions for the CDAN1 protein with ASF1A/B complexes. www.nature.com/articles/s41...
nature.com
Mechanism of ASF1 engagement by CDAN1
Nature Communications - CDAN1 is an essential protein with unclear function that binds the histone chaperone ASF1. Here, the authors reveal that CDAN1 sequesters multiple copies of ASF1 by engaging...
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The Vallee Foundation @valleefoundation.bsky.social · 19/03/2025
Congratulations to Dr David Eisenberg (2016 Vallee Visiting Professor) of UCLA who has been named the 2025 Alexander Rich Medalist by the Department of Chemistry. www.chemistry.ucla.edu/news/david-e...
chemistry.ucla.edu
David Eisenberg named 2025 Alexander Rich Medalist by the MIT Department of Chemistry – UCLA
The Paul D. Boyer Professor of Biochemistry and Molecular Biology at UCLA, Eisenberg is member of both the UCLA Department of Chemistry & Biochemistry, and the UCLA Department of Biological Chemistry, as well as a Principal Investigator and former Director of the UCLA-DOE Institute.
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The Vallee Foundation @valleefoundation.bsky.social · 19/03/2025
Watch Vallee Scholar Chris Mason (Weill-Cornell) talk about the returning astronauts today. www.foxnews.com/video/637018...
foxnews.com
Doctor explains how stranded astronauts will reacclimate to Earth | Fox News Video
Weill Cornell Medicine professor Dr. Christopher Mason joins 'Fox & Friends' to explain how nine months in space has impacted the returning astronauts' bodies.
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The Vallee Foundation @valleefoundation.bsky.social · 14/03/2025
princeton.edu
Portraits of distinguished Princetonians Ruth Simmons and Elaine Fuchs unveiled
Simmons, a former University administrator and trailblazer in higher ed, and Fuchs, a Princeton Ph.D. and renowned cell biologist, were honored in a ceremony Nov. 16.
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Reposted by The Vallee Foundation
ESB Congress @esbcongress.bsky.social · 14/03/2025
🧠 How does the brain control movement? At #ESB2025, Prof. Mackenzie Mathis will reveal insights into motor learning & the neural basis of adaptive behavior using AI-driven models like MausSpaun. 📍 ETH Zürich | 6-9 July 🔗 Learn more: esbiomech2025.org/keynote-spea... @trackingactions.bsky.social
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The Vallee Foundation @valleefoundation.bsky.social · 03/03/2025
www.insideprecisionmedicine.com/topics/trans...
insideprecisionmedicine.com
Zhang Lab Discovers Ancient RNA System That Could Simplify Gene Editing
TIGR could provide a more versatile and compact tool for gene editing, and could even overcome some limitations of CRISPR gene editing.
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The Vallee Foundation @valleefoundation.bsky.social · 22/02/2025
Meet Vallee Scholar Julian Stingele at the Ludwig Maximilians University, Munich www.lmu.de/en/newsroom/...
lmu.de
Overlooked alarm signal: RNA damage moves into the spotlight
Because RNA is relatively short lived, RNA damage was long dismissed as not that significant. In our interview, biochemist Julian Stingele explains why this view has changed.
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The Vallee Foundation @valleefoundation.bsky.social · 19/02/2025
Congratulations to Vallee Scholar Lisa Olshansky for being named a 2025 Sloan Research Fellow! Lisa's research focuses on mimicking and then leveraging the ways that biological systems use structural changes as a vehicle for the interconversion of different forms of energy.
thevalleefoundation.org
Lisa Olshansky, PhD | The Vallee Foundation
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The Vallee Foundation @valleefoundation.bsky.social · 11/02/2025
Vallee Scholar Joseph Bondy-Denomy has a paper in Nature: www.nature.com/articles/s41...
nature.com
Multi-interface licensing of protein import into a phage nucleus - Nature
This study uncovers a highly conserved jumbo phage protein, Imp1, that possesses multiple interfaces to license protein import into a proteinaceous nucleus-like compartment, using a genetic selection ...
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