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Chemistry at the University of Illinois Chicago

@uic-chemistry.bsky.social
957 followers 1.4K following 19 posts

Advancing sustainability, health, and education through innovative chemistry research at Chicago's only public research institution. Official account for the Department of Chemistry at University of Illinois Chicago. chem.uic.edu

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Reposted by Chemistry at the University of Illinois Chicago
Ruixuan Gao @ruixuan3.bsky.social · 17/10/2025
(1/x) Excited to report VIPS (Volumetric imaging of biological specimens via photochemical sectioning) @science.org! VIPS uses light-based sample sectioning to eliminate the inherent imaging depth limit of high-resolution optical microscopes @supgokul.bsky.social: www.science.org/doi/10.1126/...
science.org
Mesoscale volumetric fluorescence imaging at nanoscale resolution by photochemical sectioning
Optical nanoscopy of intact biological specimens has been transformed by recent advancements in hydrogel-based tissue clearing and expansion, enabling the imaging of cellular and subcellular structure...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 16/10/2025
The Gao lab at #UIC reports a breakthrough in volumetric fluorescence imaging, featured on the cover of Science Magazine! Their new technique, VIPS (Volumetric Imaging via Photochemical Sectioning), enables reconstruction of 3D images of whole tissues with unprecedented detail.
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 03/06/2025
🚨 New from UIC Chemistry! Led by the Hemley group, this #Science study reports the first 1-dimensional high-entropy oxide nanoribbons — materials that remain stable under extreme heat (1000°C), pressure (up to 12 GPa), and corrosive environments. Read here: tinyurl.com/2djw8phs #chemsky
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 10/05/2025
New #JACS from the Adibekian Lab, making it the 3rd JACS from #UIC Chemistry this week! 🍾🍾🍾 Read it here: pubs.acs.org/doi/10.1021/... @jacs.acspublications.org #Chemsky
pubs.acs.org
Proteome-Wide Covalent Targeting of Acidic Residues with Tunable N-Aryl Aziridines
Carboxylate side chains in aspartic and glutamic acids play critical roles in protein structure and function due to their polarity and negative charge. These acidic residues, which are abundant in hig...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 08/05/2025
🚨 New paper alert from the Nguyen lab at #UIC! @jacs.acspublications.org #chemsky
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 05/05/2025
🚨 New in #JACS: The Glusac group at #UIC has developed a new MOF composed of nanographene ligands, which acts as a photocatalyst for CO2 reduction using water as the terminal electron donor. Read here: tinyurl.com/ejpm52hx @jacs.acspublications.org @ksenia-glusac.bsky.social
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Reposted by Chemistry at the University of Illinois Chicago
Andy I. Nguyen @andy-i-nguyen.bsky.social · 25/04/2025
Pi-stacking offers powerful strategies to design structured and functional peptide materials of all dimensions. Check out our review in just out in "Trends in Chemistry"! @cp-trendschem.bsky.social www.sciencedirect.com/science/arti...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 20/04/2025
The Cho group at hashtag #UIC discovered that many colorectal cancers driven by APC loss depend on high membrane cholesterol to activate β-catenin signaling. Blocking cholesterol–Dishevelled interaction halted tumor growth without harming normal cells. #Chemsky tinyurl.com/mc5prces
tinyurl.com
Cholesterol-targeting Wnt–β-catenin signaling inhibitors for colorectal cancer - Nature Chemical Biology
Locally elevated cholesterol in colorectal cancer cells with adenomatous polyposis coli truncation was observed to drive Wnt–β-catenin signaling through Dishevelled (Dvl). Inhibitors targeting the cho...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 16/04/2025
Now in Nature Comm: The Hu group at #UIC developed NHS-ester dye labeling to tag live mammalian cell membranes for superresolution imaging—capturing dynamic protein distribution, cell-cell contacts, nanotube formation, and intercellular transfer in vivo. #Chemsky Article: tinyurl.com/rnzwnm7d
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 03/04/2025
New work from the Mankad group, published in #JACS, reveals that a bimetallic complex can generate the very rare Al(II) oxidation state that can activate CO2.
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 17/03/2025
🧪☘️ This St. Patty's Day weekend, we were proud to show prospective graduate students from around the country what UIC Chemistry and Chicago is all about!
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 10/03/2025
🚨 Check out this post-doc opportunity in the Nguyen lab!
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 28/02/2025
UIC Chemist Andy Nguyen's (@andy-i-nguyen.bsky.social) research lab, recognized with recent awards from NIH, NSF, and DOE, is approaching breakthroughs in peptides and their societal impact. Learn more about Dr. Nguyen's award-winning research: go.uic.edu/AndyNguyenat...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 26/02/2025
New work from the Adibekian group at UIC out in @J_A_C_S! "Chemoproteomics-Enabled De Novo Proteolysis Targeting Chimera Discovery Platform Identifies a Metallothionein Degrader to Probe Its Role in Cancer" Read it here: pubs.acs.org/doi/10.1021/...
pubs.acs.org
Chemoproteomics-Enabled De Novo Proteolysis Targeting Chimera Discovery Platform Identifies a Metallothionein Degrader to Probe Its Role in Cancer
Proteolysis targeting chimeras (PROTACs) represent powerful tools to modulate the activity of classically “undruggable” proteins, but their application has been limited to known ligands and a few sele...
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Reposted by Chemistry at the University of Illinois Chicago
Neal Mankad @metallacycle.bsky.social · 24/02/2025
Is there a metal-metal bond in Fp2? Check out our latest @pubs.acs.org publication to learn more: pubs.acs.org/doi/10.1021/... Thankful to collaborate with @chemmatcars.bsky.social to do the analysis 💎 #chemsky
pubs.acs.org
Comprehensive Re-examination of Intermetallic Charge Density for the Metal Carbonyl Dimers Mn2(CO)10 and [(η5-C5H5)Fe(CO)2]2
In this study, we have employed high-resolution charge density (HRCD) techniques using X-ray diffraction data collected at 10 K to reanalyze the intermetallic electron density topologies of two repres...
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Reposted by Chemistry at the University of Illinois Chicago
Julia Oktawiec, PhD @joktawiec.bsky.social · 06/02/2025
I am so excited for this opportunity! Also, very grateful to the support from past and current mentors—particularly my PhD advisor Jeff Long and my postdoc mentor Nathan Gianneschi, but also many others along the way.
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 06/02/2025
We are excited to welcome Julia Oktawiec @joktawiec.bsky.social to our faculty! The Oktawiec Lab will interface synthetic peptide-based oligomers, dendrimers, and polymers with coordination chemistry to design novel nanomaterials for sustainability and health. oktawieclab.com
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Reposted by Chemistry at the University of Illinois Chicago
Andy I. Nguyen @andy-i-nguyen.bsky.social · 22/01/2025
Our lab is grateful to receive the NSF CAREER award to further develop π-stacking porous peptide frameworks! @uic-chemistry.bsky.social new.nsf.gov/funding/oppo...
new.nsf.gov
Faculty Early Career Development Program (CAREER)
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 09/01/2025
Congratulations, Neal!
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 23/12/2024
🚨 Now in #JACS : The Ayitou lab at #UIC has reported the first aerobic photon upconversion using all-organic donor-acceptor chromophores, which can perform doublet-to-triplet energy transfer (DTET). Read it here: tinyurl.com/3ycxa4rf
tinyurl.com
Doublet Spin State Mediated Photoluminescence Upconversion in Organic Radical Donor-Triplet Acceptor Dyads
Donor–acceptor dyads are promising materials for improving triplet-sensitized photon upconversion due to faster intramolecular energy transfer (ET), which unfortunately competes with charge transfer (...
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 18/12/2024
Check out the latest work from the Mankad group!
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 26/11/2024
New paper from the Jiang lab at UIC is featured on the cover of ACS Nano! "Chemically Interrogating N-Heterocyclic Carbenes at the Single-Molecule Level Using Tip-Enhanced Raman Spectroscopy" Read it here: t.co/pLEXMqF6mm
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Reposted by Chemistry at the University of Illinois Chicago
Ioana M. ILIE @biosim-lab.bsky.social · 19/11/2024
I’ve started a starter pack on peptide design. Please suggest more colleagues to be added or let me know if you want to be added. Peptides rock! go.bsky.app/QL4rSPE
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Chemistry at the University of Illinois Chicago @uic-chemistry.bsky.social · 21/11/2024
The University of Illinois Chicago Chemistry Department is excited to join #chemsky!
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