Sign in

Toufic Mayassi

@touficmayassi.bsky.social
295 followers 170 following 23 posts

Mucosal immunologist drawn to the computational world | Bana Jabri lab graduate | Postdoc in @thexavierlab.bsky.social at the @broadinstitute.bsky.social | AstraZeneca

PostsRepliesMedia
Reposted by Toufic Mayassi
meisellab.bsky.social @meisellab.bsky.social · 09/07/2025
Our lab just completed a +6 year #marathon, describing for the first time that the #microbiome is critical for #exercise - induced increases in antitumor CD8 T cell immunity and improved of #cancer #immunotherapy. www.cell.com/cell/fulltex...
cell.com
Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy
Exercise enhances antitumor immunity and immunotherapy effectiveness by increasing microbiota-derived formate, which boosts CD8 T cell function and may serve as a biomarker of melanoma suppression.
22610
Reposted by Toufic Mayassi
Eric Topol @erictopol.bsky.social · 02/10/2025
How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite www.cell.com/cell/abstrac...
622170
Reposted by Toufic Mayassi
Ivan Zanoni @lozanzi.bsky.social · 23/11/2024
#WeekendRead! #LocationLocationLocation! Amazing @Nature by @touficmayassi.bsky.social, Xavier &co showing regional specialization of the gut at the spatial (single cell) level! Strong resilience after inflammation & ILC2 are key in middle colon adaption to microbiota! www.nature.com/articles/s41...
nature.com
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
03815
Toufic Mayassi @touficmayassi.bsky.social · 21/11/2024
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇 www.nature.com/articles/s41...
nature.com
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
813040