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Thomas Downes

@tomdownes.bsky.social
178 followers 167 following 34 posts

GP and Multimorbidity PhD Programme for Health Professionals Fellow at the University of Glasgow. Interested in clinical trial applicability, multimorbidity and polypharmacy.

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Reposted by Thomas Downes
mltcphdprogramme.bsky.social @mltcphdprogramme.bsky.social · 29/09/2026
Recruitment for Multiple Long-Term Conditions PhD Programme Cohort 1 has launched, Full list of projects - www.gla.ac.uk/postgraduate... job advert www.jobs.gla.ac.uk/job/multiple... for any queries please watch recording of the applicant webinar - youtu.be/vUaGjKW6ICU
gla.ac.uk
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deprescribing.org @deprescribing.bsky.social · 12/09/2026
We collaborated with an international team of experts to create a Prioritized List of 24 Potentially Inappropriate Prescribing Cascades published in @bmj.com: www.bmj.com/content/394/... This list will help inform future prescribing and deprescribing initiatives. Please reshare w/ your network!
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Peter Tennant @pwgtennant.bsky.social · 27/08/2026
Does the new shingles vaccine (Shingrix) protect against cardiovascular disease (CVD)? Yes, according to a new 'natural experiment' study in @natmed.nature.com. But the truth is sadly far less convincing! Pull up a chair and let's examine another peer review failure in a Nature journal. 1/10 🧵
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The Cochrane Collaboration @cochrane.org · 17/08/2026
🫱🏾‍🫲🏿 An important principle of Cochrane reviews is involving people. Did you know Cochrane has a free learning resource to support you in getting people involved in the production of your reviews? Start learning today! 🔗 www.cochrane.org/learn/course...
Involving people. Discover best practice and practical suggestions for finding and involving people throughout the review process
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Therapeutics Initiative (TI) @drug-evidence.bsky.social · 19/08/2026
🆕 UBC TI #SystematicReview 🆕 Glucagon-like peptide-1 receptor agonists for primary cardiovascular disease prevention in #T2DM drc.bmj.com/content/14/4... Current evidence insufficient to establish cardiovascular benefit of GLP-1 RAs in primary #CVD prevention #GLP1 #diabetes #MedEd
drc.bmj.com
Glucagon-like peptide-1 receptor agonists for primary cardiovascular disease prevention in type 2 diabetes, a systematic review
We aimed to estimate the cardiovascular (CV) benefit of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in patients with type 2 diabetes (T2D) without a history of CV disease (CVD) (primary CVD ...
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Thomas Downes @tomdownes.bsky.social · 20/08/2026
Fantastic opportunity to present the plan for my PhD to other fellows and directors on the Multimorbidity PhD programme for Health Professionals. Excited to get stuck in @glasgow.ac.uk
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The BMJ @bmj.com · 23/06/2026
"Looking after older, multimorbid patients is what we trained for as GPs." Frail patients are most in need of our attention as GPs, but in many cases they receive less and less of it, writes @helensalisbury.bsky.social www.bmj.com/content/393/...
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BJGP @bjgp.org · 04/06/2026
youtu.be/XC0EMoFLbbI What challenges do people of colour have in diagnosis of #Eczema #Acne and #Psoriasis? doi.org/10.3399/BJGP... #SkinOfColour #Dermatology #HealthInequalities #CulturalCompetence #BJGP #PrimaryCare #research #GeneralPractice
youtu.be
Dermatology and skin of colour
Read the research: https://doi.org/10.3399/BJGP.2025.0720 Listen to the full-length interview: https://player.captivate.fm/episode/43e1c3c8-9c94-41e0-9888-61...
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Ben Goldacre @bengoldacre.bsky.social · 24/02/2026
BIG NEWS!
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The Lancet Primary Care @lancetprimarycare.bsky.social · 13/02/2026
🆕 In their Comment, Peter Hanlon and colleagues discuss pragmatic prescribing for people with moderate or severe frailty in primary care Read the full Comment here ➡️ www.thelancet.com/journals/lan...
thelancet.com
Frailty, polypharmacy, and the case for pragmatic prescribing in primary care
Primary care clinicians are often caught between conflicting recommendations for clinical care. On one side, specialist guidelines and trial evidence urge intensive treatment, such as tight blood pres...
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BJGP @bjgp.org · 30/01/2026
Hidden harms in #End-Of-Life injectable symptom control #HealthCare: many patient safety incidents reported as 'no harm' contain descriptions of physical/psychological harm experienced by patients and families doi.org/10.3399/BJGP... @drbenbowers.bsky.social @carsonstevens.bsky.social #PrimaryCare
doi.org
Revealing the hidden harms in end-of-life care: a mixed-methods characterisation of reported safety incidents involving injectable symptom control medication | British Journal of General Practice
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Thomas Downes @tomdownes.bsky.social · 29/01/2026
Had the opportunity last week to present my research on clinical trial applicability as an elevator pitch at the #NADEGS 2026 #primarycare conference in Edinburgh. Good to chance to consolidate thoughts and highlight main points. Looking forward to next year’s turn with Glasgow!
Opening slide of the NADEGS conference listing the man speakers
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The Lancet Primary Care @lancetprimarycare.bsky.social · 13/01/2026
🆕 "The dominance of research... from mostly high-income countries means that much of the knowledge shaping primary care policy and practice reflects the priorities, populations, and health system structures of wealthier regions [limiting] the knowledge translation to the different contexts" ...
Graphical representation of the total number of primary care publications per country for the period 1975 to 2024. A map of the world, with a coloured scale showing one to more than ten thousand publications. Figure 2 of the Comment.
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Blair H Smith @blairhsmith.bsky.social · 10/01/2026
I will be honoured to deliver this lecture: www.dundee.ac.uk/events/dougl...
dundee.ac.uk
Douglas G Adamson Memorial Lecture 2026 | University of Dundee, UK
Dr Douglas G Adamson was a Consultant Physician and Honorary Senior Lecturer at the University of Dundee until his sudden death in 1979.
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The BMJ @bmj.com · 06/01/2026
"The more I support people with obesity and learn about the impact of stigma and the drivers of ill health, the less I talk about weight at all in short primary care consultations." @ellenfallows.bsky.social on reframing consultations away from numbers on scales www.bmj.com/content/392/...
Doctor talking to a patient
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Thomas Downes @tomdownes.bsky.social · 06/12/2025
Excited to see work’s started on this new active travel link in Edinburgh: www.edinburgh.gov.uk/news/article...
edinburgh.gov.uk
Construction begins on first phase of West Edinburgh Link
Construction begins on first phase of West Edinburgh Link
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The Lancet Primary Care @lancetprimarycare.bsky.social · 20/11/2025
🆕 In a single-blind RCT, topical hydrogen peroxide was compared with topic fusidic acid and simple wound hygiene in the management of non-severe impetigo lesions in school-aged children in Auckland, Aotearoa New Zealand. Read the findings of the TIARA trial ➡️ www.thelancet.com/journals/lan...
thelancet.com
Topical hydrogen peroxide versus fusidic acid for non-severe impetigo in Auckland, Aotearoa New Zealand (the TIARA trial): a single-blind, randomised controlled trial
Topical hydrogen peroxide was not non-inferior to topical fusidic acid for treatment of non-severe impetigo. However, as these infections are mild and the difference in cure rate is small, when balanc...
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Caroline Mitchell @dclovesgp.bsky.social · 02/12/2025
@bjgp.bsky.social bjgp.org/content/bjgp... Evidence-biased medicine? Applying a health equity lens to Sackett's methodological framework #GeneralPractice #DeepEndGP #FamilyMedicine #PrimaryCare @nihrspcr.bsky.social @nihrarcs.bsky.social
bjgp.org
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Thomas Downes @tomdownes.bsky.social · 03/11/2025
Are you a GP registrar about to start your out-of-hours (OOH) shifts? Or a qualified GP looking to get back into OOH? Check out our new article to help get you ready @rcgp-innovait.bsky.social #primarycare journals.sagepub.com/doi/10.1177/...
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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deprescribing.org @deprescribing.bsky.social · 24/10/2025
🎉 Congrats to Sameera Toenjes and her team for an excellent publication in @plosone.org highlighting the perspectives of primary care clinicians regarding perceived barriers, facilitators, and team roles in addressing prescribing cascades: Read the full article here! buff.ly/yscPvts
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Thomas Downes @tomdownes.bsky.social · 15/10/2025
Proud to see our research featured on my news feed this morning: Frailty index could improve life for younger patients www.bbc.com/news/article...
bbc.com
Electronic Frailty Index could improve life for younger patients
Researchers at the University of Dundee say a measure used to assess the health of older people can help younger patients.
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The BMJ @bmj.com · 02/10/2025
"Undermining confidence in one of the few safe and effective pain and fever relief drugs in pregnancy risks causing unintended harm." Pregnant women are often excluded from clinical trials and evidence gaps enable unsubstantiated claims, @louiseckenny.bsky.social www.bmj.com/content/391/...
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Caroline Mitchell @dclovesgp.bsky.social · 19/09/2025
Useful and important primary care research ⬇️ bjgpopen.org/content/earl...
bjgpopen.org
Use of unscheduled care in the last year of life for people with multiple long-term health conditions: a retrospective cohort study of 299,361 decedents
Background People living with and dying from multiple long-term health conditions are high users of healthcare services. Unscheduled care, the unplanned use of healthcare services, rises dramatically ...
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Dr Geraint Preest @drgeraintpreest.bsky.social · 17/09/2025
As we head into autumn, in many instances, patient expectations following a community acquired pneumonia can have a profound effect on repeat appointments (“I feel better but I’m still coughing, Doc”). Here’s a timely reminder from NICENG250
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Margaret McCartney @mgtmccartney.bsky.social · 01/09/2025
VERY EXCITING launch of the CENTRE FOR EVIDENCE AND VALUES IN HEALTHCARE at the Uni of St Andrews first event 31st October with Sir David Haslam and Scotland's new patient safety commissioner Karen Titchener find out more here medicine.st-andrews.ac.uk/centreforevi... please sign up and come
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Dr Kate Womersley @katewomersley.com · 02/09/2025
More women in cardiovascular trials still needed (and CVD trials are pretty good compared to other medical specialties...) jamanetwork.com/journals/jam...
jamanetwork.com
Participation of Women in Cardiovascular Trials, 2017 to 2023
This systematic review describes the representation of women across a broad range of cardiovascular trials registered from 2017 to 2023.
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Thomas Downes @tomdownes.bsky.social · 01/09/2025
The electronic frailty index (eFI) is used to identify older adults (≥65 years) who may be living with frailty. In our new study, we found that the eFI also identifies younger adults (18-64 years) at high risk of mortality and hospital admission: www.thelancet.com/journals/lan... #frailty #medsky
thelancet.com
Applicability of the electronic frailty index in younger and older adults in England: a population-based cohort study
Similarly to older adults, the eFI identifies younger adults with frailty at high risk of mortality and emergency hospital admission. The eFI might be a tool to identify individuals for further assess...
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Euan Reid @euanreid.pharmsky.app · 28/08/2025
MHRA approves UK’s first new type of antibiotic for urinary tract infections in nearly 30 years #Pharmsky #Medsky www.gov.uk/government/n...
gov.uk
MHRA approves UK’s first new type of antibiotic for urinary tract infections in nearly 30 years
As with any medicine, the MHRA will keep the safety of gepotidacin under close review.
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deprescribing.org @deprescribing.bsky.social · 25/08/2025
Ever wonder what percentage of hospital admissions are caused by medications? 💊 A systematic review published in the Age and Ageing Journal finds adverse drug reactions (ADRs) and adverse drug events (ADEs) are significant causes of hospitalization in older adults. buff.ly/4Vuv4T2
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deprescribing.org @deprescribing.bsky.social · 02/08/2025
As we age, changes in our bodies can affect drug exposure, leading to potentially increased risks of both medication toxicity and treatment failure. 💊 Great review article highlights major age-related physiological changes that can impact drug use: link.springer.com/article/10.1...
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Thomas Downes @tomdownes.bsky.social · 01/08/2025
Open letter from the heads of Scotland’s medical schools on the threat to the clinical academic workforce. “If we do not act, we risk weakening the very system that has delivered some of the most transformative advances in modern medicine” www.universities-scotland.ac.uk/clinicalacad...
universities-scotland.ac.uk
Scotland’s Quiet Crisis: Why Clinical Research Needs Urgent Rescue — Universities Scotland
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handle.invalid @handle.invalid · 28/07/2025
Our realist review from #RESOLVE study funded by @nihr.bsky.social published today @thementalelf.bsky.social @sapc.ac.uk @cmhpcommunity.pharmsky.app onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Non‐pharmacologicaL InterVEntions for Antipsychotic‐Induced Weight Gain (RESOLVE) in People Living With Severe Mental Illness: A Realist Synthesis
Introduction Antipsychotic medications are used to treat individuals with severe mental illness (SMI) but are associated with rapid weight gain and several physical and mental risk factors. Early, p.....
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Helen Salisbury @helensalisbury.bsky.social · 29/07/2025
BMA and other national medical organisations come together as a voice for doctors in Europe to call for immediate action in Gaza
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BJGP Open @bjgpopen.bsky.social · 21/07/2025
A study highlighting sex differences in antihypertensive prescription patterns and efficacy in primary care reveals that women achieve better blood pressure control with lower doses and distinct drug types. This calls for sex-specific optimisation in hypertensive management ➡️doi.org/10.3399/BJGP...
Illustrative
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Thomas Downes @tomdownes.bsky.social · 18/07/2025
Great day at the North Uist Highland Games today. Just about crossed the line in the Men’s 100m Flat Race for 2nd place!
Falling over finishing line in race.
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Euan Reid @euanreid.pharmsky.app · 30/06/2025
Polypharmacy Guidance: Appropriate Prescribing Making medicines safe, effective and sustainable 2025-2028 Scottish Government: Effective Prescribing & Therapeutics Division Consultation on Draft Guidance #Pharmsky #Medsky www.gov.scot/publications...
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Frank Moriarty @frankmoriarty.bsky.social · 27/06/2025
Just ten days left to apply for this Research Fellow position, focused on pharmacoepidemiology and deprescribing. More information about the DIAMOND programme available at: diamond-deprescribing.eu Full job description here (deadline July 7th): my.corehr.com/pls/rcsirecr...
diamond-deprescribing.eu
Home
DIAMOND is an ambitious Wellcome-funded programme of research that aims to develop and advance novel methods for researching deprescribing by harnessing big data.
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Journal of Multimorbidity and Comorbidity @jmultimorbidity.bsky.social · 23/06/2025
Hello 👋. We are the official BlueSky account of the Journal of Multimorbidity and Comorbidity - part of Sage Journals @journals.sagepub.com
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Euan Lawson @euanlawson.social · 18/06/2025
The impact factors for 2024 are published today - *sigh* - so this is a good moment to send people to the editorial I wrote last month about them, the BJGP, and QRPs/journalology. #primarycare #BJGP bjgp.org/content/75/7...
bjgp.org
Medical journalology and questionable research practices
The BJGP is the world’s leading journal in primary care and general practice. I’m happy to defend this assertion but the temptation is to reach for a metric to support the case. And of course, the obv...
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Ben Goldacre @bengoldacre.bsky.social · 13/06/2025
Please can we fund the NHS and care by taxing the housing wealth of the over 60s? At time of death, if you like. This is huge, unearned money, and going to drive damaging inequality at inheritance. Taxing workers and businesses is much worse for the economy. www.theguardian.com/business/202...
theguardian.com
Britain on track to become a ‘National Health State’, says thinktank
Resolution Foundation says half of all public spending will be allocated to the NHS and social care by the end of the decade
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Thomas Downes @tomdownes.bsky.social · 30/05/2025
Buzzing that our GP practice team won the prize for best overall costumes and decorared pram at the annual Penicuik pram race 2025 🐝 m.youtube.com/watch?v=AKFC...
m.youtube.com
Penicuik Pram Race 2025
YouTube video by Top Scotch
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BJGP @bjgp.org · 21/05/2025
Starting an antidepressant is associated with a 2-4-fold increased risk of postural hypotension in the first month in people aged ≥60 years doi.org/10.3399/BJGP... #PrimaryCare #Antidepressant #Hypotension #GeneralPractice #Research
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Helen Salisbury @helensalisbury.bsky.social · 20/05/2025
"Our analysis also shows the vampiric nature of extreme wealth, which is completely incompatible with the health and wellbeing of the nation,” said Priya Sahni-Nicholas, co-executive director of the Equality Trust Well said my cousin Priya www.theguardian.com/news/2025/ma...
theguardian.com
UK’s 50 richest families hold more wealth than 50% of population, analysis finds
Equality Trust says billionaires getting ‘ludicrously’ richer, with top two now wealthier than whole of 1990 rich list
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Tim Senior @timsenior.bsky.social · 07/05/2025
I've worked in the same clinic for 20 years now. I never thought I'd be in one place for so long. I had a few thoughts on being a GP for a long time in the @bjgp.bsky.social bjgplife.com/how-long-doe...
bjgplife.com
How long does general practice take?
"... to my surprise, I’ve become the sort of doctor that has been in the same clinic for 20 years. I’ve never been bored, I’ve often been anxious, and I’ve been privileged to witness some of
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Lucy Pollock @lucypgeridoc.bsky.social · 26/04/2025
doi.org/10.1136/ejhp... Super article - drug errors cause so much harm but this is an optimistic article identifying ways to help - systems, tech, support for fallible humans 👏👏👏👏
doi.org
Tackling medication errors: how a systems approach improves patient safety
Objectives Medication errors are a leading source of preventable harm in healthcare, affecting approximately 1 in 30 patients, with a substantial proportion resulting in severe outcomes. In response, ...
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Helen Salisbury @helensalisbury.bsky.social · 26/04/2025
When your Royal College and the BMA says PAs should have have a nationally set, limited scope of practice and always be supervised by senior doctors, but GMC is fine with them working autonomously with locally defined scope - ask yourself who is protecting patients from harm?
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Thomas Downes @tomdownes.bsky.social · 21/04/2025
Super useful reference including key AI definitions and an approach on how to read a paper including AI in its research. Reminder that “AI… is not a panacea, and it raises both practical and ethical challenges”.
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Rob Ralston @policyrelevant.bsky.social · 18/04/2025
doing archival research for a paper on processed foods and single-use plastics, and it is striking how companies like Coca-Cola have been able to delay meaningful environmental action by making the same voluntary commitments over and over This is from 1999, but could literally be from last year
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Ageing Clinical and Experimental Research Team Uni. of Aberdeen @acer-aberdeenuni.bsky.social · 27/03/2025
Our team want to know how those aged 65 years and older feel about accessing primary care health services, and if they would access these services if they had questions about their medicines. Click here for more information: redcap.link/inform #agingresearch #ageingresearch #polypharmacy
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