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Tomas Pachano

@tomaspachano.bsky.social
89 followers 166 following 8 posts

PostDoc in the Stark lab at the IMP, Vienna. Studying how pathogens rewire human cells

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Reposted by Tomas Pachano
Belen Pachano @belenpachano.bsky.social · 25/08/2026
Excited to share our new work in @natcomms.nature.com on GCN5b in Toxoplasma gondii! 🧬🦠 Huge thanks to everyone who contributed to this work! Specially Dominique and the amazing @hakimi.bsky.social 🎉 www.nature.com/articles/s41...
nature.com
Divergent SAGA complexes shape the Toxoplasma transcriptome for lytic cycle progression and host interaction - Nature Communications
Researchers show that the zoonotic parasite Toxoplasma gondii built a unique chromatin modifying complex to activate the genes that drive infection and virulence, revealing a potential weak spot for n...
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Reposted by Tomas Pachano
Mikko Taipale @miketilapia.bsky.social · 30/06/2026
Our evil ORFeome paper is out! In collaboration with @alex-stark.bsky.social, we screened ~4,000 viral proteins and secreted effectors from bacteria and parasites, covering hundreds of diverse pathogens, for phenotypes in human cells.
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Tomas Pachano @tomaspachano.bsky.social · 30/06/2026
I am thrilled to share our paper out in @cp-cell.bsky.social : "Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways." (1/4) www.cell.com/cell/fulltex...
cell.com
Systematic discovery of pathogen effector functions across human pathogens and pathways
The eORFeome, a large-scale collection of open reading frames encoding viral proteins and secreted bacterial and parasite effectors, enables functional genomics across diverse pathways and pathogens. ...
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Reposted by Tomas Pachano
IMP @impvienna.bsky.social · 30/06/2026
Pathogens have spent millions of years learning how to hijack human cells. Now, researchers from the Stark lab at the IMP and the Taipale lab at the Donnelly Centre, University of Toronto, have built a platform to systematically discover how they do it:
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