Co-option of primate-specific retroelements creates an alternative IL-13Rα1 subunit that tunes type 2 immune responses.

This Review addresses the roles of type 2 immunity in cancer and the potential for cancer immunotherapies targeting this pathway.

Structural analysis reveals species-specific differences in how the antibody IgE binds to its receptor FcεRI.

Abstract. Selfish genetic elements comprise significant fractions of mammalian genomes. In rare instances, host genomes domesticate segments of these eleme

Lymph node IL-2 microniches guide development of TH2 cells through induction of Blimp-1 expression and an IL-10–positive feedback loop.