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Thierry Nordmann

@tnordmann.bsky.social
83 followers 25 following 6 posts

Skin-Scientist, MD-PhD, Applying Spatial & Single-Cell Clinical Proteomics in Dermatology, Husband, Father of 3 💫🔬

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Thierry Nordmann @tnordmann.bsky.social · 26/06/2025
A must-read, landmark paper by @lisaschweizer.bsky.social - hands down one of the most accomplished scientists I know. Congratulations👏 @mannlab.bsky.social @lengyel-ovca-lab.bsky.social bsky.app/profile/mann...
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Mann Lab @mannlab.bsky.social · 26/06/2025
Our paper on ovarian cancer #LGSC is out in @Cancer_Cell. Using deep visual proteomics #DVP and spatial transcriptomics, we mapped how non-invasive tumors become deadly ovarian disease, and found a promising new treatment combination. www.cell.com/cancer-cell/...
cell.com
Spatial proteo-transcriptomic profiling reveals the molecular landscape of borderline ovarian tumors and their invasive progression
Schweizer et al. profile the tumor progression from non-invasive serous borderline tumors of the ovary to metastatic low-grade serous ovarian cancer. By integrating cell-type resolved Deep Visual Prot...
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Max Planck Institute of Biochemistry @mpibiochem.bsky.social · 02/05/2025
Since April, @tnordmann.bsky.social has been leading a research Group @mpibiochem.bsky.social. He has now been awarded the prestigious Oscar Gans Prize by the German Dermatological Society. Congratulations and welcome! #award #dermatology #proteomics @mannlab.bsky.social
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Nature Portfolio @natureportfolio.nature.com · 17/01/2025
In patients with diffuse intrinsic pontine glioma, a rare, fast-growing and fatal pediatric brain tumor, local delivery of B7-H3 targeting CAR T cells was feasible and well tolerated with a median overall survival of 19.8 months, according to a trial reported in Nature Medicine. #MedSky 🧪
go.nature.com
Intracerebroventricular B7-H3-targeting CAR T cells for diffuse intrinsic pontine glioma: a phase 1 trial - Nature Medicine
In the final report of a phase 1 trial evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from diagnosis.
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Mann Lab @mannlab.bsky.social · 14/01/2025
Our mipDVP workflow integrates 22-marker imaging with Deep Visual Proteomics to spatially map cell-type proteomes in hot/cold tumors, revealing distinct immune landscapes, macrophage barriers, T cell adaptations to hypoxia & tumor heterogeneity. Online in Molecular Cell. doi.org/10.1016/j.mo...
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Eric Topol @erictopol.bsky.social · 28/12/2024
My favorite books, 2024
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Mann Lab @mannlab.bsky.social · 20/12/2024
Looking forward to a fabulous 2025, full of happiness and scientific achievements! 🔬💫
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Thierry Nordmann @tnordmann.bsky.social · 07/12/2024
Spatial proteomics is Method of the Year 2024 @naturemethods.bsky.social!🎉🤩 Grateful to share our perspective on spatial proteomics with the great Matthias Mann and Andreas Mund, alongside inspiring colleagues shaping this exciting field - this is just the beginning 💫 www.nature.com/articles/s41...
nature.com
A new understanding of tissue biology from MS-based proteomics at single-cell resolution - Nature Methods
Spatial mass spectrometry (MS)-proteomics is a rapidly evolving technology, particularly in the form of Deep Visual Proteomics (DVP), which allows the study of single cells directly in their native en...
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Eric Topol @erictopol.bsky.social · 08/12/2024
www.nature.com/articles/s41... Commentary by @tnordmann.bsky.social Editorial @naturemethods.bsky.social www.nature.com/articles/s41...
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Thierry Nordmann @tnordmann.bsky.social · 07/12/2024
Spatial proteomics is Method of the Year 2024 @naturemethods.bsky.social!🎉🤩 Grateful to share our perspective on spatial proteomics with the great Matthias Mann and Andreas Mund, alongside inspiring colleagues shaping this exciting field - this is just the beginning 💫 www.nature.com/articles/s41...
nature.com
A new understanding of tissue biology from MS-based proteomics at single-cell resolution - Nature Methods
Spatial mass spectrometry (MS)-proteomics is a rapidly evolving technology, particularly in the form of Deep Visual Proteomics (DVP), which allows the study of single cells directly in their native en...
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Ying Zhu @nanopots.bsky.social · 06/12/2024
After long-time review, #nanoSPLITS is finally published. I am deeply grateful to my colleagues who made this work possible, especially @cajunscience.bsky.social. I am also grateful to the support of our single-cell proteomics community during the peer review on Nature Communication!
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Marie Will, MD, PhD @marie-will.bsky.social · 27/11/2024
A bench-to-bedside targeted therapy story! Fatal disease ➡️ patient samples ➡️ deep proteomics ➡️ find target (jak/stat) ➡️ realize drugs exist ➡️ try drugs in lab ➡️ it works! ➡️ give drugs to patients ➡️ holy cow it actually works!!!! ➡️ save lives. This is the dream. Nice work @tnordmann.bsky.social
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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 24/11/2024
Wow—one of the most impressive bench-to-bedside stories you’re ever going to see out today @Nature Spatial proteomics of potentially fatal toxic epidermal necrolysis/Stevens-Johnson Syndrome drug reactions identifies JAK/STAT pathway inhibition as effective therapy! www.nature.com/articles/s41...
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Itai Yanai @itaiyanai.bsky.social · 18/11/2024
Science twitter is dead! Long live science twitter! 🦋
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Vadim Demichev @vadim-demichev.bsky.social · 16/11/2024
First BlueSky post :)
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Eric Topol @erictopol.bsky.social · 26/10/2024
The Dawn of Spatial Medicine Until now, spatial omics was used to understand human biology. That changed when it saved lives of patients with a fatal skin condition. In the new Ground Truths erictopol.substack.com/p/the-dawn-o...
erictopol.substack.com
The Dawn of Spatial Medicine
For the first time spatial omics leads to a lifesaving treatment
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