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Terren Niethamer

@tniethamer.bsky.social
374 followers 927 following 4 posts

Mom, scientist, Stadtman Investigator at NCI. Excited about 🫀endothelial cells in 🫁 lung development and regeneration. Views my own.

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Reposted by Terren Niethamer
NAVBO @navbo.bsky.social · 22/01/2026
Join us for an interactive #NAVBO online panel! 🚀 “Ethical and Effective Use of AI,” on January 27, 2026 at 1PM ET, organized by the Growth and Enrichment Committee. Register here 👉 members.navbo.org/ap/Events/Re...
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Reposted by Terren Niethamer
Kara McKinley @karalmckinley.bsky.social · 23/07/2025
A beautifully written piece on a terrible time www.science.org/content/arti...
science.org
My academic job offer was rescinded. I’ll keep going—but U.S. researchers are running out of road
Despite an uncertain future, this postdoc will “keep doing the science I love while I still have a bench”
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Reposted by Terren Niethamer
The Jackson Laboratory @jax.org · 21/07/2025
Scientists have corrected gene mutations in mice causing an ultra-rare disease by editing DNA directly in the brain with a single injection, a feat with profound implications for patients with neurological diseases. 🧬🧠🔬🧪
jax.org
Genome Editing Corrected Rare Brain Mutations in Mice. Could It Help Fight Neurological Diseases?
Expert mouse models and genetic research at JAX drive scientific breakthroughs, ensuring precision and reliability in advancing medical discoveries.
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Reposted by Terren Niethamer
Abby Polter @ampolter.bsky.social · 15/05/2025
I am thinking a lot today about how heavy things feel in my world of faculty doing scientific research. There's the immediate chaos and panic about our ability to pay people and continue our research. But there's also a deeper grief at watching everything get bulldozed for no reason
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Reposted by Terren Niethamer
Edward Nirenberg @enirenberg.bsky.social · 29/03/2025
Peter Marks’s resignation letter. Everyone should read this.
Peter Marks, MD, PhD
Director, Center for Biologics Evaluation and Research U.S. Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20903
March 28, 2025
Sara Brenner, MD, MPH
Acting Commissioner of Food and Drugs
U.S. Food and Drug Administration
10903 New Hampshire Avenue
Silver Spring, MD 20903
Dear Dr. Brenner:
It is with a heavy heart that I have decided to resign from FDA and retire from federal service as Director of the Center for Biologics Evaluation and Research effective April 5, 2025. I leave behind a staff of professionals who are undoubtedly the most devoted to protecting and promoting the public health of any group of people that I have encountered during my four decades working in the public and private sectors. I have always done my best to advocate for their well-being and I would ask that you do the same during this very difficult time during which their critical importance to the safety and security of our nation may be underappreciated.
Over the past years I have been involved in enhancing the safety of our nation's blood supply, in advancing the field of cell and gene therapy, and in responding to public health emergencies. In the last of these, during the COVID-19 pandemic I had the privilege of watching the vision that I conceived for Operation Warp Speed in March 2020 in collaboration with Dr. Robert Kadlec become a reality under the leadership of HHS Secretary Azar and President Trump due to the unwavering commitment of public servants at FDA and elsewhere across the government. At FDA, the tireless efforts of staff across the agency resulted in remarkably expediting the development of vaccines against the virus, meeting the standards for quality, safety, and effectiveness expected by the American public. The vaccines undoubtedly markedly reduced morbidity and mortality from COVID-19 in the United States and elsewhere. Many of these same individuals applied learnings from the pandemic during a flawless response helping…ongoing multistate measles outbreak that is particularly severe in Texas reminds us of what happens when confidence in well-established science underlying public health and well-being is undermined.
Measles, which killed more than 100,000 unvaccinated children last year in Africa and Asia owing to pneumonitis and encephalitis caused by the virus, had been eliminated from our shores. The two-dose measles, mumps, rubella vaccine regimen (MMR) using over the past decades has a remarkably favorable benefit-risk profile. The MMR vaccine is 97% or more effective in preventing measles following the two-dose series, and its safety has been remarkably well studied. Though rarely followed by a single fever-related seizure, or very rarely by allergic reactions or blood clotting disorders, the vaccine very simply does not cause autism, nor is it associated with encephalitis or death. It does, however, protect against a potential devasting consequence of prior measles infection, subacute sclerosing panencephalitis (SSPE), which is an untreatable, relentlessly progressive neurologic disorder leading to death in about 1 in 10,000 individuals infected with measles. Undermining confidence in well-established vaccines that have met the high standards for quality, safety, and effectiveness that have been in place for decades at FDA is irresponsible, detrimental to public health, and a clear danger to our nation's health, safety. and security.
In the years following the pandemic, at the Center for Biologics Evaluation and Research we have applied the same unwavering commitment to public health priorities to the development of cell and gene therapies to address both hereditary and acquired rare diseases. During my tenure as Center Director we have approved 22 gene therapies, including the first gene therapy ever to be approved in the United States. However, we know that we must do better to expedite the development of treatments for those individual suffering from any one of the thousan…
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Reposted by Terren Niethamer
@LaBonneLaB @labonnelab.bsky.social · 13/03/2025
Dear all, Because of your help shining light on this all 15 were reinstated today. This is a huge win for science - When We Fight We Win!!!
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Terren Niethamer @tniethamer.bsky.social · 24/02/2025
It's been a whirlwind of a month for me, but I want to take a moment to say I am so excited for this paper to be out! If you are interested in how the lung responds to injury and how it regenerates (or doesn't...) please go take a look! tinyurl.com/4r4zttkv
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bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · 15/02/2025
MYRF is Essential in Mesothelial Cells to Promote Lung Development and Maturation www.biorxiv.org/content/10.1101/202…
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Reposted by Terren Niethamer
Joanna Pylvänäinen @jwpylvanainen.bsky.social · 30/01/2025
I put together a small guide on how to get started with Fiji. Please distribute to anyone who might benefit form this! zenodo.org/records/1477... #imageanalysis #fiji #imagej #training
zenodo.org
Image handling using Fiji - training materials
Description:This training package provides a guide to image processing and analysis using ImageJ/Fiji, an open-source software widely used in biological and medical imaging. The manual includes step-b...
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Terren Niethamer @tniethamer.bsky.social · 26/11/2024
Same on both counts 😂
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Reposted by Terren Niethamer
Tom Chadwick @thomasbchadwick.bsky.social · 23/11/2024
nature.com
A STAT3–STING–IFN axis controls the metastatic spread of small cell lung cancer - Nature Immunology
Here, the authors show that signal transducer and activator of transcription 3 (STAT3) has dual functions in small cell lung cancer as its deletion inhibited primary tumor growth but boosted metastati...
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Terren Niethamer @tniethamer.bsky.social · 17/11/2024
We are your neighbors and friends! ❤️
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Reposted by Terren Niethamer
bioRxiv Cancer Bio @biorxiv-cancer.bsky.social · 15/11/2024
Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer www.biorxiv.org/content/10.1101/202…
biorxiv.org
Basal cell of origin resolves neuroendocrine-tuft lineage plasticity in cancer https://www.biorxiv.org/content/10.1101/2024.11.13.623500v1
Neuroendocrine and tuft cells are rare, chemosensory epithelial lineages defined by expression of AS
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Reposted by Terren Niethamer
Stephanie Geuns-Meyer @geunsmeyer.bsky.social · 13/11/2024
Strong receptor-ligand binding affinity #ChemistsWhoCook
A close-up view of freshly-cooked shell pasta (Annie's white mac & cheese) with green peas (previously frozen). There are a smaller number of peas than shells, but each is nestled snuggly in a shell as if purposely stuffed
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Reposted by Terren Niethamer
Matthew Freeman @mjafreeman.bsky.social · 12/11/2024
Waves of new BlueSky arrivals in last few days! I’ve been tracking starter packs relevant to molecular/mechanistic/genetic/cellular…etc biology Hope it’s helpful but warning: now a v long thread! Probably the last time I can do this...
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Terren Niethamer @tniethamer.bsky.social · 13/11/2024
Hello BlueSky! I'm a #newpi in #devbio at #NCI interested in how endothelial cells in blood vessels help build and repair tissues - can't wait to talk science with you all! 🫀🫁
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