iiinova — where your digital self keeps evolving

Elegant Sledgehammer FREE LINK @tinyteerex.bsky.social · 3h

It helps so much to know that, especially after this weekend. 💜

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And we all need to demand this of our elected Or, we elect someone else, or even impeach. I believe with every fiber, that Biden believed b e l i e v e d his mandate from the People was 'get back to Normal', hence the election of the Moderate, the man who always crossed the aisle. Yeah...

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Emma Evans @trance.bsky.social · 6h

IF or WHEN the dems have the majority in both Houses We the People have to be up in their shit, on their asses, screaming at them like they owe us money Remember, Trump was a one term POTUS...and now we're back in the shit. Because nothing changed, nothing really got DONE. Accountability.

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It’s Julie. Dr. Tilsen, if you’re nasty (or use AI) @queeringtherapist.bsky.social · 8h

Bumper is not here to get a book.

Dog sitting next to a treat box staring at the sign that says “MacLarens Dog Library”

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Elegant Sledgehammer FREE LINK @tinyteerex.bsky.social · 8h

We put out a giant plastic bowl on each side of our gate (outside the fence) and let folks help themselves while we're out trick or treating with our kids. Hiring a student to hand out candy is also a great idea!

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Amber Ying 應緣 @amberying.com · 8h

I get that people want to suggest that being an asshole is deviant from "good" behavior, but just take a moment to think about the logical conclusion whenever you say that the deviance means crazy.

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Amber Ying 應緣 @amberying.com · 8h

Some of you are getting too comfy saying that billionaires, AI tech bros, and all the other assholes have to have some psychiatric condition because being a complete utter greedy mean-spirited troll of a person must mean they're crazy. As an actual "crazy" person, fuck you.

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Bub 🏳️‍🌈 🐈 @bubotomy.bsky.social · 8h

Me.

Today I completed a chore I have been putting off for 7 months. It took 12 minutes. I will learn nothing from this.

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Arrianna Marie Planey, PhD MA @arrianna-planey.bsky.social · 8h

I still think about how the absence of consent is foundational to the business model. For example, at least 37 of my articles were used to train OpenAI's models.

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Arrianna Marie Planey, PhD MA @arrianna-planey.bsky.social · 8h

Non-consensual, hard-to-avoid "use" of GenAI (like asbestos shoved into every crevice) does not invalidate critique of GenAI (primarily, its political economy of resource extraction, labor exploitation, &c)

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Gail Simone @gailsimone.bsky.social · 17h

You guys want to hear a short but adorable story that happened right in front of me at the baggage claim in NYC yesterday? I wasn't part of it and there are bits I didn't catch but holy crap, I can't stop thinking about it.

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Gail Simone @gailsimone.bsky.social · 16h

And she said, "I hope you don't mind, I have been watching a little bit. I want you to know I am so proud."

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Doctors for Safer Drug Policy @dsdp.ca · 10h

We graded the candidates based on their responses and did not take into account any other factors related to their candidacy. For a full transcript of the questions we asked and the candidates’ answers, see here: docs.google.com/document/d/1...

docs.google.com

Victoria Candidate Q&A Transcript

Questions (1) What specific actions and commitments are you willing to make to reduce deaths and harms from the current Toxic Drug Crisis? (2) What is your stance on harm reduction initiatives, inc...

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Doctors for Safer Drug Policy @dsdp.ca · 10h

We put a set of community-sourced questions to all the municipal candidates in Victoria, covering a range of issues that are important to us. #bcpoli #YYJ #Victoria #harmreduction #toxicdrugcrisis #housingcrisis

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Doctors for Safer Drug Policy @dsdp.ca · 10h

Did Not Answer The following candidates did not answer our survey: Wendy Bowkett Herb Collins (Herbert) Melissa K Cseszko Shona Dion Marg Gardiner Darren Gervais-Harrison Christopher Hanna Stephen Hammond @stephenhammond.bsky.social Arthur McInnis Gregoor Miller Karen Rothe

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Tom Kindlon @tomkindlon.bsky.social · 10h

New from France Interesting long Covid research where all participants satisfy ME/CFS criteria Evidence for transcriptomic changes impacting muscle contraction in patients with post-acute COVID-19 syndrome www.sciencedirect.com/science/arti... #LongCovid #MEcfs #PwME #CFS #postcovid #postcovid19

Post-acute COVID-19 syndrome (PACS) overlaps with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) but, due to frequent muscle pain and exertional intolerance, neuromuscular disorders are often suspected. We report the results of a comprehensive neuromuscular evaluation in 27 PACS patients (22F/5M; median age 41 ys). All patients developed chronic fatigue (>6 months), post-exertional malaise, and cognitive impairment, with muscle pain in 88% but no neuromuscular deficits at clinical examination. 18/27 patients were unable to work. All patients fulfilled established ME/CFS diagnostic criteria (CDC 1994, ICC 2011, Inst Medicine 2015, NICE 2021). Electrophysiological studies and CK levels were normal. Brain 18FDG-PET/MRI (14/27) showed posterior hypometabolism in 8/14. Muscle biopsy (7/27) showed moderate dysimmune changes in 2/7. Exploratory transcriptomic analyses performed in muscle biopsies from PACS patients and pre-COVID controls unveiled in PACS differentially expressed genes in the cytokine and autophagy pathways. Interestingly, other genes were also differentially expressed in pathways affecting actin, the cytoskeleton, and contraction. Indeed, we found upregulated genes involved in the troponin-tropomyosin complex, a key regulator of muscle contraction through calcium binding. We also found downregulated genes involved in the formation and stabilization of actin bundles at sarcomere Z discs and in mechanical signaling. These findings indicate that PACS patients with prominent muscular symptoms do not exhibit overt neuromuscular involvement on standard investigations but may show subtle myopathic or dysimmune changes and central metabolic alterations. At the transcriptomic level, the data show an impact on key pathways involved in contraction. The overlap with ME/CFS highlights the importance of careful differential diagnosis and suggests a complex pathophysiology beyond a basic muscle disease.

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Flying Leviathan @ Hell, Actually (Read Pinned 📌) @flyingleviathan.bsky.social · 9h

We have the room! Thank you all so much. Now we just need money for food. Please help us some more. 💸💕 #HomelessSky

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Kelly @broadwaybabyto.bsky.social · 10h

We know very little about the plague outbreak in Russia We know it happened in a lab We know one person died They’ve saying it’s pneumonic It’s state sponsored media so we must take it with a grain of salt One thing is certain, there’s no harm in wearing a mask! Covid & flu are raging too!

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🇬🇾🗽Sydette The Dreaded Gorgon🗽🇬🇾 @blackamazon.bsky.social · 10h

Everyone is going to get the racism they set the stage for . Everyone is gonna get the “just askin(“ “free speech world “ they wanted And everyone will automatically blame the targets of that racism rather than the people who engineered this

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Carceral Abolition @carceralabolition.bsky.social · 10h

French education minister says up to 500 schools could remain closed on Monday after student protests – as it happened At least 5,000 people, mainly teenagers, have been arrested while dozens of people, including students and teachers, have been injured www.theguardian.com/world/live/2...

theguardian.com

French education minister says up to 500 schools will remain partially or fully closed on Monday after student protests – Europe live

At least 5,000 people, mainly teenagers, have been arrested while dozens of people, including students and teachers, have been injured

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victoria scott @victoriascott.bsky.social · 12h

I do still talk to lots of people who have different politics than me because I’m a communist but all I’m doing is basically selling people on “socialism” instead of “barbarism” and if they’re a good person it’s usually a pretty easy sell

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victoria scott @victoriascott.bsky.social · 12h

You’re not just debating them, you’re debating a 24/7 firehose of information that floods every channel they listen to, with billions of dollars backing it, that affirms their gut beliefs, that were built on the basic assumptions America has made about other people.

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victoria scott @victoriascott.bsky.social · 12h

re: winning people over on “the other side” by having discussions - as someone who spent most of her early transition in the public eye, that used to work a little (at extreme psychological cost), *but those days are over*. You cannot have a discussion that overpowers this right wing ecosystem.

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Carceral Abolition @carceralabolition.bsky.social · 10h

Gazan teacher builds free school in Egypt for children displaced by war www.arabnews.com/middle-east/...

arabnews.com

Gazan teacher builds free school in Egypt for children displaced by war

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Robert Rose @robear.bsky.social · 14h

A good fresh Star Trek take on those fake isekai title jokes

A tumblr screenshot showing a post and two reblog responses, reading:
1. "star trek would be the ideal fictional universe to get trapped in because you'd explain your situation and they'd be like yeah makes sense. no further questions. fortunately we can use the mysterious warp signature emitting from this system's icy moon to counterface with the solar radiation and slingshot you back home"
2. "I'm from a universe where your world is all a work of fiction." Benjamin Sisko, nodding. "That happened to me once."
3. "I Got Isekaid Into The Star Trek Universe And They Quickly Understood What Was Happening"

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Mozelle Batiste Delacroix’s only son. @roamingdruid.bsky.social · 10h

I know it’s been talked into the ground. But I really dislike the fact that a coterie of alleged rapists are being called the “Cornell 7” it evokes. The “ Central Park 5” who were a group of 5 Black boys accused of raping a white woman back in 1989, who were legally exonerated in

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Elegant Sledgehammer FREE LINK @tinyteerex.bsky.social · 9h

Fuck Shoppers & fuck the Westons, too. Our independent pharmacist is right across the street & will stay a few minutes late to make sure we can pick meds up in time (bless him).

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