iiinova — where your digital self keeps evolving

Tim Feinstein @timnfeinstein.bsky.social · 8h

La Carreta in Miami airport. No joke one of the better Cuban restaurants in a town with a lot of great Cuban food.

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Tim Feinstein @timnfeinstein.bsky.social · 05/10/2026

Kia ora! You’re in photographer paradise.

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Tim Feinstein @timnfeinstein.bsky.social · 02/10/2026

Can’t remember the author, Clarke maybe. Astronomers cleaning out a colleague’s office find a couple WOW! (extraterrestrial) radio signals buried in his safe. After puzzling it, out they realize they’re ciphers (so probably military), and the two sources are ~ as far apart as each is from Earth.

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Tim Feinstein @timnfeinstein.bsky.social · 02/10/2026

I had a great pitch for satan back in ye olde days when door knockers were more common. I don’t believe in him either but as a literary character he’s quite interesting

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Tim Feinstein @timnfeinstein.bsky.social · 01/10/2026

Joining the six month Friedman Unit (time before we can start judging the Iraq war) and the ten year window to fusion making net energy

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Tim Feinstein @timnfeinstein.bsky.social · 30/09/2026

Cold dew, soaked in shoes Dog poos in the gloaming light Breath fog, there and gone.

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Reposted by Tim Feinstein

Prasad Jallepalli, MD, PhD @prasad.bsky.social · 29/09/2026

5 potatoes cubed is still 5 potatoes because potatoes are root vegetables

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Tim Feinstein @timnfeinstein.bsky.social · 28/09/2026

That’s already done in aerospace, but the methods and costs are way beyond what you’d have in mind when you think ‘3D printing’. That only makes sense if you’ve already strong armed local governments to write blank subsidy checks and you literally can’t metabolize any more cocaine

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Tim Feinstein @timnfeinstein.bsky.social · 28/09/2026

Damage was already done. The last time the Times was relevant, they spent 2016 getting walked on a leash by a small group of Giuliani-loyal ‘sources’ inside the FBI. Events after that left the NYT behind entirely.

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Tim Feinstein @timnfeinstein.bsky.social · 28/09/2026

I don’t think most people will ever appreciate how the New York Times got walked on a leash by Giuliani’s old crew at the FBI New York Field Office (NYFO) in 2016. All sides of the coverage, NYT got told what to print and then printed it as told. Lichtblau’s OCT surprise was just the most obvious.

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Tim Feinstein @timnfeinstein.bsky.social · 28/09/2026

(Derpy is btw the unofficial consensus name of the demon cat, per my daughter)

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Tim Feinstein @timnfeinstein.bsky.social · 27/09/2026

TEM: it’s all fun and games until someone reads a MSDS.

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Tim Feinstein @timnfeinstein.bsky.social · 27/09/2026

You can learn a lot from someone’s attitude towards controlling women

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

We went through this already with the last Iraq war. It is really really really hard to just ‘make’ bioweapons. You can’t just fire up an incubator and go nuts with the NEB catalog. The infrastructure’s almost as easy to spot from its footprint as an atomic weapons lab.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

Really thrilled to see the Shokat lab get this recognition. His structure-guided mutation assays opened up a completely new field in kinase studies.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

Congrats! He was an inspiration in my thesis work. Completely groundbreaking approaches to enzyme structure-function studies.

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Elizabeth Anne, PhD @lacksauthority.bsky.social · 26/09/2026

do I have any followers that are cetacean experts? I got a few shots today of a dolphin (looks bottlenose to me) that is either extremely well-fed or pregnant and would love some more informed opinions

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

You gotta KNOW the recipes for alkaline lysis buffers 1 and 2. Not just have them taped up over the DNA bench like normals do

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

(if you cover it before it starts cooling, stuff can’t really get in and start growing in the 20 hours before you heat it up again)

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

Am I the only one who thinks these keep getting better each subsequent day? I think it has to do with re-heating cycles releasing flavors better. My wife makes a great bolognese, French style, and we just leave the Creuset on the stove covered for the 3-4 days it takes to finish.

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Sanho Tree @sanho.bsky.social · 26/09/2026

Happy Stanislav Petrov day! He saved the world from nuclear annihilation on this day in 1983. My freshman year in college would have been so much worse without his courage.🧵

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

What a great set! As much as I grump about phones vs traditional cameras, you have to admit that all that processing sometimes makes the shot, like the sun through that arch. I got this in Rome, there must be > six stops of light between the shadows and the basilica.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

Yeah, that’s a problem. Apparently it’s a plague with high school aged guys.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

How did this macro lens even get here

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

I sure can’t wait until investors force AI companies to rectify their balance sheet by charging market rate for their services.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

In that regard gambling hasn’t changed at all. If DraftKings had a carpet, looking at it too long would cause brain damage.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

If people think Caribbean writing styles are prone to false positives, that sounds like a testable question. We can’t have all these vague rules being applied arbitrarily and sloppily like this.

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Tim Feinstein @timnfeinstein.bsky.social · 26/09/2026

So give every book the same test. I don’t like any part of this story, but singling this one guy out smells especially bad.

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The Marine Biological Association @thembauk.bsky.social · 26/09/2026

Enter your ocean photos! 🌊📸 5 Days left to enter our 2026 Ocean Photography Competition! 📅 Deadline: Friday 30th September 2026🔗 Details & Submission: www.mba.ac.uk/ocean-image-collection/ Thank you to Framed Picture Company, CRC Press, MacLehose Press and @princetonupress.bsky.social

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

Can you combine STED with FLIM? That would be a heck of a scope.

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Cells & Development @cellsdev.bsky.social · 25/09/2026

We heard through the vines that #cilia are hot (or not?) right now so here is a cool article by the Saxena lab about how Notch signalling inhibit zebrafish olfactory multiciliated cells differentiation 🐟 AND we got a cool movie with it too! #FluorescenceFriday www.sciencedirect.com/science/arti...

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

Cheeky. And congrats to the Saxena lab!

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Vaughn Cooper @vscooper.micropopbio.org · 25/09/2026

FYI to everyone submitting this October NIH cycle You need to re-certify your ScienCV AFTER Sept 26 (tomorrow) for your application or it may not be accepted. Great timing!

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

I go off about the atomists here. bsky.app/profile/timn...

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

But about taking things a bit ad absurdum, have you read Lucretius? His De Rerum Natura is basically an epic poem stanning Democritus and the atomists, and the number of fields it touches on is wild. The cosmology really isn’t bad for some guys working things out from first principles over dinner.

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

SciFinder Scholar was soooo good for that.

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

I wanna say the marine calcium cycle, but that’s only because I wrote a long monograph on it for Bob Whitlach’s class and I remember some heavy duty original sources in German

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

Nuclear fallout (tubulin cross-linker, the background story is great)

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

For chrissake, don’t solve the puzzles

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

You have to pay attention to billionaires because they’re billionaires, especially when whole economies have bent themselves around your specific company. And it’s too many words to write ‘CEO of OpenAI, whose path to profitability most resembles Heath Ledger playing the Joker…’ in every headline.

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

No such thing in oceanography school in the states. No rings, or swords for that matter, or even a rubber duck (as cool as that would be). Just a proper grilling, a handshake, and a diploma in the mail.

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Tim Feinstein @timnfeinstein.bsky.social · 25/09/2026

That popping up in The Discourse has to be inspired by Critical Role, right? I was just wondering what ‘cold iron’ was all about, and now I know! I figured it was just unworked somehow. Scientists don’t have a ring or oath, for those wondering. Maybe bc most experiments don’t work anyway.

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Tim Feinstein @timnfeinstein.bsky.social · 24/09/2026

There’s a big, you might call it, activation energy barrier when you go from picture-oriented microscopy to analysis-oriented microscopy. Just a really big gap. If you don’t get it from a tough mentor early on (I was lucky there) then it’s hard to pick it up on your own later.

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Tim Feinstein @timnfeinstein.bsky.social · 24/09/2026

Pause while the patient waits for the phone to form a reply

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Tim Feinstein @timnfeinstein.bsky.social · 24/09/2026

Saw Hari Shroff give a talk on that some years ago at ASCB. It worried me not so much because of what he was doing, as where people would go with the idea when it got more accessible. Watch next for ‘super-resolution’ images taken with a widefield and extrapolated.

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