Early in insect embryo development, many nuclei share one large cell, travel varied paths and self-organize into a single layer. Donoughe et al. illuminate this process with live-imaging, modeling, an...

Summary: The multinucleated embryo of the fruit fly D. melanogaster distributes nuclei with the help of centrosome-organised microtubule asters, with ordering dynamically adapting to synchronous nucle...

By modelling epithelial cells as active nematic liquid crystals, stresses induced at the sites of topological defects are found to be the primary drivers of extrusion and cell death.

Embryonic development leads to the reproducible and ordered appearance of complexity from egg to adult. The successive differentiation of different...

Cell fates endowed by higher Bicoid concentration require input for longer duration, demonstrating a temporally non-linear morphogen-mediated pattern formation.

The transcription factor Bicoid (Bcd) establishes patterning in the early Drosophila blastocyst through its graded concentration along the anterior-posterior (AP) axis. bcd mRNA is maternally deposite...

This two-day meeting will focus on Quantitative Cell and Developmental Biology. We will bring expertise from across scales, combining people working on subcellular cell biology through to tissue scale...