Poly(ADP-ribose) (PAR) is an RNA-like homopolymer synthesized by enzymes in response to DNA damage. Increasing evidence indicates that PAR participates in di...

Ions and temperature jointly regulate RNA structure, dynamics, and phase behavior, yet their coupled effects remain poorly understood at the molecular level. Single-stranded RNA (ssRNA), a ubiquitous ...

Electrostatic interactions mediated by surrounding ions critically influence RNA behavior, yet flexible RNAs remain underexplored. We performed molecular dynamics simulations to examine three RNAs acr...

Electrostatic interactions mediated by the surrounding ions govern virtually every facet of RNA behavior. Most studies have focused on rigid, well-folded motifs, leaving the structurally heteregeneous...

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HHS would be asked to absorb a $40 billion cut, about one-third of its discretionary budget.

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