Reposted by @tianasophiabehr.bsky.socialSvetlana Dodonova @dodonova-sveta.bsky.social · 30/09/2026New preprint from Dodonova lab 🔔! Capturing multiple states by cryo-EM❄️, we show for the first time how archaeal RNA Polymerase engages a nucleosome and forms direct contacts with histones! 🧬 Great work by Gabriele & a fantastic collaboration with Dina Grohmann! 🧵 www.biorxiv.org/content/10.6... 19936
Reposted by @tianasophiabehr.bsky.socialsimon-alkema.bsky.social @simon-alkema.bsky.social · 17/09/2026Releasing TOMATO, the TOMogram Annotation TOol! A lightweight Python GUI for going through hundreds of cryo-ET tomograms. Flag what's in each one, grade its quality, and end up with a table you can filter and act on. github.com/alkemasimon/... 15825
Reposted by @tianasophiabehr.bsky.socialmaxseidel.bsky.social @maxseidel.bsky.social · 19/06/2026📢 (1/2) Excited to share the first preprint from my PostDoc! We developed UbSeRP to map co-translational ubiquitination in a translatome-wide, revealing thousands of quality control sites, and how they reshape with aging. www.biorxiv.org/content/10.6... #proteostasis #ribosomes #preprintbiorxiv.orgUbiquitin selective ribosome profiling reveals systematic principles of co-translational quality controlProtein biogenesis is a stress- and error-sensitive process that can lead to nascent protein misfolding and aggregation, challenging cellular proteostasis. Co-translational ubiquitination (CTU) is a c... 14818
Reposted by @tianasophiabehr.bsky.socialmdreimann.bsky.social @mdreimann.bsky.social · 19/06/2026Super excited to share my first paper from my PhD in the @dodonova-sveta.bsky.social lab. We visualise how chromatin from archaeal cells is organised using cryo-ET and SPA. Big thanks to everyone involved in this project! 1389
Reposted by @tianasophiabehr.bsky.socialSvetlana Dodonova @dodonova-sveta.bsky.social · 19/06/2026Excited to share our new preprint! 🧬❄️ by brilliant @mdreimann.bsky.social and great collaborators! Using cryo-ET&EM, we reveal archaeal chromatin in a near-native state: variable-beads-on-a-string fibers shaped by growth phase and histone composition #ArchaeaSky www.biorxiv.org/content/10.6... 815363
Reposted by @tianasophiabehr.bsky.socialSvetlana Dodonova @dodonova-sveta.bsky.social · 16/12/2025Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky 24327
Reposted by @tianasophiabehr.bsky.socialRasmus Jensen @rasmusjensen.bsky.social · 19/11/2025Tired of knowing what you are looking for in your tomograms? Why not try bluesky-less Frosina's new self-supervised algorithm for semantic segmentation and particle picking for #teamtomo (includes a new denoiser without the need for odd/even tomos) Code is on GitHub if you want to try it out 05111
Reposted by @tianasophiabehr.bsky.socialThe Daum Lab @daumlab.bsky.social · 29/10/2025We are looking for an enthusiastic postdoc to investigate cellular dormancy and ribosome hibernation across plants, fungi, and mammals using #cryoET. If you are interested, apply here: careers.exeter.ac.uk/vacancies/66.... 0199
Reposted by @tianasophiabehr.bsky.socialNature @nature.com · 31/07/2025This surprisingly relaxing footage is from SIX MILES under the ocean – and it’s the deepest ecosystem yet discovered 427140903396
Reposted by @tianasophiabehr.bsky.socialPilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 12/08/2025Check out 🧐 our new preprint 📜: www.biorxiv.org/content/10.1... Congrats🎉 to @vasilgaisin.bsky.social and Corina Hadjicharalambous, who studied contractile injection systems directly in hot spring♨️ bacterial mats🦠 #microsky #teamtomo #Chloroflexota 36625
Reposted by @tianasophiabehr.bsky.socialXabier Vázquez-Campos @xabivc.bsky.social · 23/07/2025Our new preprint with a new #Asgard from stromatolites (and its Desulfobacterota companion). Complete circularised genomes of both, cool #cryoem images, protein modelling, etc Big group effort with a lot of people involved #archaeasky #archaea www.biorxiv.org/content/10.1...biorxiv.orgAn Asgard archaeon from a modern analog of ancient microbial matsIt has been proposed that eukaryotic cells evolved via symbiosis between sulfate-reducing bacteria and hydrogen-producing archaea. Here we describe a highly enriched culture of a novel Asgard archaeon... 65220
Reposted by @tianasophiabehr.bsky.socialBiomedical Picture of the Day BPoD @bpodaily.bsky.social · 02/06/2025Tau filaments (magenta here) tether to the membrane of extracellular vesicles in Alzheimer's disease patient brains 📷 Stephanie L. Fowler & Tiana S. Behr et al Benjamin Ryskeldi-Falcon & Karen E. Duff @ukdri.ac.uk @mrclmb.bsky.social @nature.com Neuroscience ➡️ bpod.org.uk/archive/2025... 083
Reposted by @tianasophiabehr.bsky.socialSvetlana Dodonova @dodonova-sveta.bsky.social · 26/05/2025We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social! www.biorxiv.org/content/10.1... #Chromatin #Asgard #Archaea #cryoEM 13238101
Reposted by @tianasophiabehr.bsky.sociallizzieenglish.bsky.social @lizzieenglish.bsky.social · 13/04/2025🚨 NEW PAPER: must-read for researchers, funders & institutions 🚨 👩🔬 >50% of female dementia researchers experience sexism in their careers. 🏫 5x more respondents found their institution NOT helpful than helpful in addressing this. ➡️ Learn more: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...alz-journals.onlinelibrary.wiley.comExperiences and perceptions of sexism in dementia research careers: A global cross‐sectional surveyINTRODUCTION Sexism is prevalent in academia and is a crucial factor driving women out of the academic workforce. However, sexism in dementia research remains underexplored. This study aimed to unde..... 1116
Reposted by @tianasophiabehr.bsky.socialIMPRS on Cellular Biophysics @imprs-cbp.bsky.social · 04/02/2025Apply by February 7 to join our IMPRS on Cellular Biophysics! 👉 imprs-cbp.mpg.de/call-for-app... @goetheuni.bsky.social @maxplanck.de #FluorescenceNanoscopy #STEDNanoscopy #SuperResolutionMicroscopy #MembraneBiophysics 📷 (1, 3, 4, 5, 6) Till Stephan Group, Goethe University Frankfurt 074
tianasophiabehr.bsky.social @tianasophiabehr.bsky.social · 26/11/2024So happy to finally see this published 🎊🎊🎊🎊Thanks again to my former supervisor @brfalcon.bsky.social and my co-first @stephfowler.bsky.social & the Duff Lab Go an have a read on either the paper or how alzforum reported on this part of my PhD journey 192