Artificial intelligence may transform molecular biology not by always providing the correct answer, but by exploring mechanistic possibilities unconstrained by the assumptions that shape expert thinking. Its greatest contribution may be exposing the intellectual blind spots of scientists, while experimental validation remains the ultimate arbiter of truth.

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Structural analysis reveals that the type VI secretion system effector cargo is enclosed within hexameric Hcp3 rings that form sequentially to enable effector loading and delivery by the Pseudomonas aeruginosa H3-type VI secretion system.

Nature Microbiology, Published online: 27 May 2026; doi:10.1038/s41564-026-02363-xStructural analysis reveals that the type VI secretion system effector cargo is enclosed within hexameric Hcp3 rings that form sequentially to enable effector loading and delivery by the Pseudomonas aeruginosa H3-type VI secretion system.

Gallego-del-Sol et al. show that arbitrium-coding phages can sense non-cognate peptide signals from other phages to regulate lysis-lysogeny decisions. This crosstalk affects lysis-lysogeny outcomes of...

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

The Grantham Institute - Climate Change and the Environment invites PhD applications that support projects in some of our priority research areas. In...

The Grantham Institute - Climate Change and the Environment invites PhD applications that support projects in some of our priority research areas. In...

Adherent-invasive strains of E. coli are commonly isolated from patients with Crohn’s disease. Here, the authors show that an AIEC harbours a hybrid Type IV secretion system (T4SS) that mediates pilin...

Google's AI co-scientist is proving itself more than a novelty. In two biology studies, it generated exciting ideas that could have taken years of lab work to uncover.

Dr Morgan Beeby’s lab has discovered how some flagella - tiny ‘tail’ propellers used by bacteria for swimming - evolved to be more powerful.

Google has launched a new AI tool called Co-Scientist. How good is it?

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AI models have been proposed for hypothesis generation, but testing their ability to drive high-impact research is challenging, since an AI-generated hypothesis can take decades to validate. Here, we ...

An unreleased system designed to assist researchers has the potential to “supercharge science”, according to Imperial researchers.

Some mobile genetic elements spread among unrelated bacterial species through unknown mechanisms. Recently, we discovered that identical capsid-forming phage-inducible chromosomal islands (cf-PICIs), ...

npj Antimicrobials and Resistance - Cpx-signalling in Yersinia pseudotuberculosis modulates Lipid-A remodelling and resistance to last-resort antimicrobials