Tahir Ali @tahirali-biomics.bsky.social · 24/09/2026The genome is being held between two requirements: 𝒓𝒆𝒎𝒆𝒎𝒃𝒆𝒓 𝒆𝒏𝒐𝒖𝒈𝒉 𝒕𝒐 𝒑𝒆𝒓𝒔𝒊𝒔𝒕; 𝒄𝒉𝒂𝒏𝒈𝒆 𝒆𝒏𝒐𝒖𝒈𝒉 𝒕𝒐 𝒆𝒙𝒑𝒍𝒐𝒓𝒆. 000
Tahir Ali @tahirali-biomics.bsky.social · 24/09/2026Reading Adami’s Chapter 1, I kept returning to one question: what must be true before evolution can accumulate anything at all? Copy. Variation. Differences that matter. tahirali-biomics.github.io/posts/2026-0...tahirali-biomics.github.ioWhat does evolution need in order to work? – Dr. Tahir AliA reading note on the Darwinian minimum—inheritance, heritable variation and selection—and the question that stayed with me: what has to be true before evolution can write anything into a genome? 000
Tahir Ali @tahirali-biomics.bsky.social · 22/09/2026The real measure of a university’s research culture is not what policies say—it is what happens when accountability becomes uncomfortable. Academic bullying thrives when power outweighs principle, and when protecting reputations becomes easier than protecting people www.nature.com/articles/d41... 020
Tahir Ali @tahirali-biomics.bsky.social · 20/09/2026𝐖𝐡𝐞𝐧 𝐭𝐰𝐨 𝐠𝐞𝐧𝐨𝐦𝐢𝐜 𝐥𝐚𝐧𝐠𝐮𝐚𝐠𝐞 𝐦𝐨𝐝𝐞𝐥𝐬 𝐚𝐠𝐫𝐞𝐞, 𝐡𝐚𝐯𝐞 𝐭𝐡𝐞𝐲 𝐥𝐞𝐚𝐫𝐧𝐞𝐝 𝐭𝐡𝐞 𝐬𝐚𝐦𝐞 𝐛𝐢𝐨𝐥𝐨𝐠𝐲—𝐨𝐫 𝐦𝐞𝐫𝐞𝐥𝐲 𝐭𝐡𝐞 𝐬𝐚𝐦𝐞 𝐬𝐭𝐚𝐭𝐢𝐬𝐭𝐢𝐜𝐚𝐥 𝐩𝐚𝐭𝐭𝐞𝐫𝐧𝐬? This is the question behind PopGenLM Bench v0.3.0. Explore the project: tahirali-biomics.github.io/popgenlm.html 1/8tahirali-biomics.github.ioPopGenLM Bench | Tahir AliPopGenLM Bench — reproducible evaluation of genomic language-model variant scores with population-genetic and evolutionary evidence. 100
Tahir Ali @tahirali-biomics.bsky.social · 16/09/2026Two tRNA sites may each vary, yet change together to preserve a base pair. The relationship reveals what either site alone cannot. My Genomes to AI note explores what this means for genomic AI. tahirali-biomics.github.io/posts/2026-0... #Genomics #LLM #BiologicalInformation #ScientificAItahirali-biomics.github.ioMeaning Lives Between Things – Dr. Tahir AliA personal reading note on joint and conditional probability, sequence context and predictive relationships in DNA. 030
Tahir Ali @tahirali-biomics.bsky.social · 09/09/2026Mendel never saw a gene or DNA. From patterns in peas, he inferred something hidden. My Genomes to AI note traces inheritance’s journey into information—and explores why AI scores need observation and validation. tahirali-biomics.github.io/posts/2026-0...tahirali-biomics.github.ioWhen Life Became Legible – Dr. Tahir AliMy first reading note on how inheritance became a measurable problem of biological information. 000
Tahir Ali @tahirali-biomics.bsky.social · 03/09/2026𝐅𝐫𝐨𝐦 𝐆𝐞𝐧𝐨𝐦𝐞𝐬 𝐭𝐨 𝐀𝐈: Using AI is not the same as knowing how to build and test it for science. I’m documenting my journey from evolutionary genomics toward evidence-grounded AI engineering—carefully, openly and honestly. tahirali-biomics.github.io/genomes-to-a... #ScientificAI #Genomicstahirali-biomics.github.ioGenomes to AI | Tahir AliGenomes to AI - Dr Tahir Ali’s working journal of becoming a scientific AI engineer. 000
Reposted by Tahir AliXavier Picó @xavierpico.bsky.social · 31/08/2026The 4th AoB Plants issue is out @aobp.bsky.social You’ll find papers on plant diversification, flower morphology evolution, seed dormancy and ecology, root ecology, embolism, and more #PlantScience #PlantResearch #PlantBiology #Botany Check it out at academic.oup.com/aobpla/issue... 0149
Reposted by Tahir AliItai Yanai @itaiyanai.bsky.social · 31/08/2026Advice for new PhD students: choose a mentor who is committed to your training, not just your project. The most important product of your PhD - even more important than the science - is YOU, a newly trained scientist. 517240
Reposted by Tahir AliNoah Whiteman @nkwhiteman.bsky.social · 06/08/2026I’m thrilled to share that our search for a tenure-track colleague in my *truly wonderful and collegial* Genetics, Genomics, Evolution and Development Division in the MCB Department at Berkeley @berkeleymcb.bsky.social is live! Please share this broad search widely: aprecruit.berkeley.edu/JPF05481aprecruit.berkeley.eduAssistant Professor -Genetics, Genomics, Evolution, and Development - Molecular and Cell BiologyUniversity of California, Berkeley is hiring. Apply now! 0183232
Tahir Ali @tahirali-biomics.bsky.social · 21/07/2026In every quiet bloom, the universe leans closer — reminding us how small wonders keep the world alive. 000
Tahir Ali @tahirali-biomics.bsky.social · 20/07/2026What if lectures didn't end when class finished? Meet Population Genetics Coach(Beta)—an AI-supported learning companion built from university teaching. Interested in using it or creating one for your course? Let's connect. Try it: tahirali-biomics.github.io/teaching/cou... #EdTech #BiologyEducation 010
Reposted by Tahir AliPetra Michaela @petramichaela.bsky.social · 18/07/2026Every silent hive is a warning for our future. Bees pollinate the crops that feed the world, support biodiversity and keep ecosystems alive. If their buzz disappears, nature's balance begins to fade. Protect bees today—because saving them means protecting our food, our planet and future generations.static.klipy.comFlying Bee Dusting Flower for PollenALT: Flying Bee Dusting Flower for Pollen 9868227
Reposted by Tahir AliScience Magazine @science.org · 12/07/2026Frozen, fossilized squirrel poop uncovered from Arctic ground squirrel burrows—some of it hundreds of thousands of years old—is shedding light on ice age ecosystems, thanks to its DNA. scim.ag/4fdoxxoscim.agFrozen squirrel poop rewrites rodent evolution, reveals new details about mammothsDNA from ground squirrel coprolites offers an unusually detailed record of ice age ecosystems 0496
Reposted by Tahir AliScience Magazine @science.org · 11/07/2026In the absence of ambient light–dark cycles, fruit flies use their behavior to create artificial cycles, restoring clock function in the brain and the normal organization of sleep and locomotor activity, according to new research. Learn more in a new #SciencePerspective: scim.ag/4flVxo7 0458
Tahir Ali @tahirali-biomics.bsky.social · 11/07/2026This illustration captures a simple truth: when we remove complexity from our ecosystems, we also remove life. Protecting biodiversity starts with how we manage our land. 020
Reposted by Tahir AliAbiotic Stress in Plants @abioticstress.bsky.social · 11/07/2026Distinct #regulatory networks mediate plant #adaptation to multifactorial #abiotic stress combinations: rethinking of plant stress #genetics www.sciencedirect.com/science/arti... #PlantScience #PlantStress @aliraza6.bsky.social @sciplant.bsky.social @plant-sci.bsky.social @planteditors.bsky.socialsciencedirect.comDistinct regulatory networks mediate plant adaptation to multifactorial abiotic stress combinations: rethinking of plant stress geneticsPlants in natural environments often encounter multifactorial abiotic stress combinations that trigger regulatory responses distinct from those trigge… 0126
Reposted by Tahir AliGraham Coop @gcbias.bsky.social · 10/07/2026Californian #BloomScrolling ~7k feet in Sierras. 1201
Reposted by Tahir AliTuuli Lappalainen @tuuliel.bsky.social · 10/07/2026We're recruiting! An open functional genomics postdoc position at @scilifelab-ngi.bsky.social / my lab / Robert Månsson lab. Top notch environment for technology and applications development in lovely Stockholm. Please spread the word or apply if interested: www.kth.se/lediga-jobb/...kth.seKTH | Postdoc in genomicsKTH jobs is where you search for jobs at www.kth.se. 01321
Reposted by Tahir AliNew Phytologist @newphyt.bsky.social · 22/06/2026#Viewpoint: Using herbarium collections to study genetic responses to global change Eckert et al 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... #LatestIssue #PlantScience @lucaseckert.bsky.social @cameronso.bsky.social 0168
Reposted by Tahir AliNandita Garud @nanditagarud.bsky.social · 30/06/2026We are very excited to share our latest. We thought that soft sweeps would be the only type of sweep spreading across human gut microbiomes. Turns out many are hard! Reach @peterlaurin.bsky.social 's thread on why! And tomorrow at #SMBE2026 I will share this work and more! 14017
Reposted by Tahir AliRegina Fairbanks @reginafairbanks.bsky.social · 18/06/2025Pleased to share that my first, first-author publication was published yesterday in @pnas.org ! We (me + @jrossibarra.bsky.social) did a little bit of detective work to better understand the age and origin of a mutation that played a key role in maize domestication. doi.org/10.1073/pnas... (1/n) 24210
Reposted by Tahir AliScience Magazine @science.org · 08/07/2026An artificial neural network built into a computer memory chip reconstructs the human cortex with high accuracy in real time. Learn more in a new #SciencePerspective: scim.ag/4wkiVrK scim.agComputing in a memory with physicsAn artificial neural network built into a computer memory chip reconstructs the human cortex with high accuracy in real time 0346
Tahir Ali @tahirali-biomics.bsky.social · 07/07/2026A butterfly on a flower feels like pure poetry, yet it is also an evolutionary negotiation — colour signals, nectar rewards, co‑adaptation. When we observe nature closely, wonder and mechanism meet. The beauty is never accidental — it is shaped by pressures, histories, and ecological relationships. 060
Reposted by Tahir AliT. Ryan Gregory 🇨🇦 @tryangregory.bsky.social · 07/07/2026As a scientist who is frustrated by poor reasoning in the literature and who teaches biology as well as philosophy of science, I can tell you that science training definitely needs to include more philosophy and history. The people who always pit STEM vs. the humanities would like to destroy both. 110436
Reposted by Tahir AliAnthony Ricciardi @ecoinvasions.bsky.social · 05/07/2026Quote: "Invasions are not just about which species arrive, but about how multiple newcomers interact with one another once they do. Co-invasions can affect ecological communities far beyond what single-species approaches predict." #bioinvasions #invasivespecies www.anoleannals.org/2026/06/14/i...anoleannals.orgInvaders Don’t Come Alone: Rethinking Biological Invasions Through Co-invasionSpecies invasions are usually studied one at a time, but ecosystems rarely have that luxury. This project began with a simple frustration: while reading about invasive predators, invasive competito… 0114
Reposted by Tahir AliCate Macinnis-Ng @loraxcate.bsky.social · 05/07/2026Warmer winters may not be as damaging as summer heatwave but they still influence natural and agricultural systems, often in hidden ways. Here's the print version - 0123
Tahir Ali @tahirali-biomics.bsky.social · 05/07/2026Open Science Before It Had a Name Steven Henikoff showed what openness can do long before it became a movement — sharing tools from Erase‑a‑Base to CUT&Tag that reshaped genomics and empowered researchers everywhere. Open science isn’t a slogan; it’s what drives discovery.🔗 lnkd.in/eZxTECy3 100
Reposted by Tahir AliCarl T. Bergstrom @carlbergstrom.com · 04/07/20261. A bit of evolutionary biology. I'm really intrigued by a new perspective piece from Steve Frank that explores connections between how natural selection creates systems that generalize and recent work in machine learning about the surprising capabilities of massively overparameterized systems.academic.oup.comGeneralization as the great leap in evolvability: insights from machine learningAbstract. Natural selection encodes learned information in the genome. Learned solutions may be tuned specifically to past challenges, failing in altered e 9402118
Reposted by Tahir AliMoi Expósito-Alonso (MOILAB) @mexpositoalonso.bsky.social · 01/12/2025Was a pleasure to talk with Emma MacKenzie from Innovative Genomics Institute about "Behind the Scenes" featured article on how I got into science, evolution, Arabidopsis, climate adaptation, and California! Article: innovativegenomics.org/news/behind-...innovativegenomics.orgBehind the Science: Moi Expósito-AlonsoBehind the Science: Moi Expósito-Alonso - Innovative Genomics Institute (IGI) 0112
Tahir Ali @tahirali-biomics.bsky.social · 02/07/2026SMBE 2026 — A wake‑up call Genetic diversity is collapsing, and global policy is still treating it as optional. Spp have already lost >10% of their genetic variation — the very engine of adaptation & survival. Scientists are raising the alarm. 🔗 genetic-diversity-scientists-warning.github.iomoisesexpositoalonso.orgM O I L A BM O I L A B rapid evolutionary genetics in a changing world 020
Reposted by Tahir AliMoi Expósito-Alonso (MOILAB) @mexpositoalonso.bsky.social · 02/07/2026Had a great time in the plenary! Here a partial view from the stage when the room did a live voting on understanding genetic diversity! #smbe2026 2513
Reposted by Tahir AliSociety for Molecular Biology and Evolution @official-smbe.bsky.social · 02/07/2026Day 4 comes, day 4 goes.... An intense week is coming to an end. See you tomorrow for the last sets of talks and the closing ceremony of #SMBE2026! 051
Reposted by Tahir AliSociety for Molecular Biology and Evolution @official-smbe.bsky.social · 02/07/2026It's the last day of #SMBE2026, and after last night's party, some groggy eyes are spotted in the crowd... Thankfully, we have @mexpositoalonso.bsky.social to reinvigorate ourselves with an inspiring plenary talk on adaptation in the Anthropocene. 0113
Tahir Ali @tahirali-biomics.bsky.social · 02/07/2026#SMBE2026 — A wake‑up call Moisés Expósito‑Alonso showed the hard truth: genetic diversity is collapsing, and global policy is still treating it as optional. Species have already lost >10% of their genetic variation — the very engine of adaptation and survival. 098
Tahir Ali @tahirali-biomics.bsky.social · 01/07/2026Great to present our latest work at #SMBE2026 in Copenhagen! Using temporal genomics in natural populations of Arabidopsis lyrata, we asked whether standing genetic variation can support rapid adaptation under contemporary climate change. 0102
Reposted by Tahir AliSociety for Molecular Biology and Evolution @official-smbe.bsky.social · 01/07/2026Nandita Garud... takes us to day 4 with her plenary talk on microbiome evolution! @nanditagarud.bsky.social #SMBE2026 1154
Tahir Ali @tahirali-biomics.bsky.social · 30/06/2026PlantCAD2 is emerging as a new‑generation DNA model that pushes genome‑wide effect‑size prediction far beyond what first‑generation DNA language models ever reached. #SMBE26 000
Reposted by Tahir AliAaditya Narasimhan @aaditya320.bsky.social · 30/06/2026Lots of interest (understandably so) in balancing selection/graph based methods in popgen (S07) #SMBE2026 072
Reposted by Tahir AliSociety for Molecular Biology and Evolution @official-smbe.bsky.social · 29/06/2026The Graduate Student Excellence Symposium started the afternoon of #SMBE2026 day2 We are honoured to have welcomed eight excellent communications from Wei-Han Lin, Nadia Haghani, Ira Zibbu, Anjali Gupta, Jialin Wei, Oya Inanli, François Frejacques, and Arthur Matte! Thank you! #society 1224
Reposted by Tahir AliSociety for Molecular Biology and Evolution @official-smbe.bsky.social · 28/06/2026We're excited to announce the second edition of the SMBE Fellows Program! ✍️ 🔗 smbe.org/smbe-fellows-program The SMBE Fellows Program provides mentorship to early-career researchers in scientific writing for evolutionary and molecular biology by writing Highlight articles for MBE and GBE. #society 1156
Tahir Ali @tahirali-biomics.bsky.social · 28/06/2026A wonderful start to #SMBE26 Sharing moments from the talk and celebrating the leadership of Juliette de Meaux. Standing genetic variation reminds us that diversity is strength—in genomes and in people. Resilience begins with many voices, many alleles, many possibilities. @official-smbe.bsky.social 030
Tahir Ali @tahirali-biomics.bsky.social · 28/06/2026A wonderful start to #SMBE26. Sharing moments from the talk and celebrating the leadership of Juliette de Meaux. Standing genetic variation reminds us that diversity is strength — in genomes and in people. Resilience begins with many voices, many alleles, many possibilities. 010
Tahir Ali @tahirali-biomics.bsky.social · 28/06/2026🚆✨ #NoFlySMBE After a very long and honestly exhausting 16‑hour train journey from Cologne — including a 6‑hour wait in Hamburg — I finally made it to Copenhagen. Tired, but really happy to arrive. 🌍💚Slow travel isn’t always easy, but it feels meaningful. Excited to see you all at #SMBE2026 — 🚆✨ 120
Tahir Ali @tahirali-biomics.bsky.social · 27/06/2026🚆✨ #NoFlySMBE I’m heading to #SMBE2026 Copenhagen by train this evening — a long 16‑hour trip with a 5‑hour pause in Hamburg, but fully worth it for a lower‑carbon journey. 🌍💚 Let’s make #NoFlySMBE and #NoFlyAcademics visible. Slow travel can still be meaningful. See you in Copenhagen, by rail. 🚆✨ 092
Reposted by Tahir AliTony Allen-Mills @taminf.bsky.social · 25/06/2026When I first spotted this butterfly a couple of hours ago, the first thing I had to do was stop my hands shaking. It's one of the rarest butterflies in France, a vanishing species in much of Europe. It's the mountain Apollo (Parnassius Apollo). Just in time for #InsectThursday #lepidoptera 17466221020
Reposted by Tahir AliJeff Spence @jeffspence.github.io · 22/06/2026Excited to see @jonj-udd.bsky.social's fantastic work out @genetics-gsa.bsky.social. Selection in _heterozygotes_ is the primary force shaping allele frequencies of loss-of-function mutations in humans, even in genes only associated with purely recessive diseases. 🧪🧬 doi.org/10.1093/gene...doi.orgAllele Frequencies at Recessive Disease Genes are Mainly Determined by Pleiotropic Effects in HeterozygotesAbstract. The classic theory of mutation-selection balance predicts the equilibrium frequency of genetic variation under negative selection. The model pred 26844
Tahir Ali @tahirali-biomics.bsky.social · 20/06/2026Working at the intersection of AI, LLMs, genomics, and evolution, I agree: AI accelerates, but expertise drives. The real question is no longer “Can you use AI” but “Do you know when it’s right—and when it only looks right?” Excellent read: www.nature.com/articles/s41... 031
Tahir Ali @tahirali-biomics.bsky.social · 09/06/2026Excited to present at SMBE 2026 in Copenhagen! I’ll be sharing new work using LLM‑based genome prediction to detect selection and rapid climate‑driven adaptation. #smbe2026 #Genomics #AITools #ClimateAdaptation #populationgenetics #AIinScience #evolutionarybiology #climatechange #aiscience 072