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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 26/05/2026

I thought I'd never publish again when transitioning from postdoc to startup founder. Today we proved that wrong as I am happy to share our latest @immunewatch.bsky.social paper on applying TCR-epitope models for TIL-therapy together with Harari and Coukos: www.sciencedirect.com/science/arti...

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Pieter Meysman @pmeysman.bsky.social · 20/05/2026

Modern cancer immunotherapies are highly personal, tuned to a specific individual. Highly effective and extremely cool, but how do we do quality control on something that is unique? What if we combined ever cheaper NGS with state-of-the art annotation tools? www.sciencedirect.com/science/arti...

sciencedirect.com

Applications of T-cell receptor specificity annotation models for quality control and immunomonitoring in adoptive T-cell therapies

Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is a powerful candidate immunotherapy. However, the personalized production proc…

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 19/05/2026

Voel me verrassend genoeg nu als ondernemer terug vrijer om te bepalen welke onderzoeks en ontwikkelingstaken ik wil prioritiseren. Trade-off is wel het heel toepasbaar onderzoek/ontwikkeling moet zijn. Maar dat heeft me van nature altijd wel iets meer geïnteresseerd.

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 19/05/2026

"Werken als doctorandus op Europese onderzoeksprojecten marcheerde niet" Kan ik me perfect voorstellen! Ik had met mijn IWT-beurs veel vrijheid tijdens doctoraat, maar tijdens postdoc op EU Grant moest ik iets meer "in het gareel dat 4 jaar ervoor bepaald was" lopen.

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 09/04/2026

We're testing something new: access ImmuneWatch DETECT through an MCP integration with Claude. Let me know if you'd like to try it out: xvx5k3zru3y.typeform.com/to/Wq7egCwo

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/02/2026

Must be quite a bill, staying 14 years in a hotel room in Ottawa 😂 Congrats on getting this out!!!

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/02/2026

For the latest episode of The Repertoire Room Podcast, I sat down with Samra Turajlic after her talk at The Festival of Genomics and Biodata. "We could only understand this because we were able to track the clones through TCR sequencing." Check it out on YouTube: www.youtube.com/watch?v=QnRd...

youtube.com

Multiomics and TCR Sequencing in Immunotherapy | Repertoire Room Ep. 5

YouTube video by ImmuneWatch

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 20/02/2026

Is it possible that in the newest update of Spotify, I can not switch from VIDEO mode to AUDIO only mode anymore? I used to be able to switch very easily and now it seems some button disappeared as I just can't figure it out. Super annoying

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 12/02/2026

Well thank you for doing all the work. Going from potential computational matches to real in-depth validation, nice to see that in one paper!

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 12/02/2026

Taking our score-cutoff of 0.23 it does confidently says 86333_1456 is a match, while for the other two not. Especially if you narrow down to the separate chain level, then it has its doubt about the specificity of the alpha chains... In any case, thanks for sharing!

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 12/02/2026

Hi Joe, Good stuff. Thanks for clearly pointing out these edge cases! But of course, I wondered if ImmuneWatch DETECT would have a clear separation between your reactive EBNA3A TCRs and non-reactive ones. It's always easy in hindsight so take it for what it's worth 😉

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/01/2026

I'll be in London at the festival of Genomics later this week. Hit me up if you want to connect!

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/01/2026

I can imagine that this must also have been a rough week for you. All the best during these hard times. Thanks for the write-up

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 19/01/2026

One of my favourite pics of Peer. Took this one on a summer day in 2021 during a lab get-to-together at his place. Cheer to you too Peer. #PeerBork

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Wolfgang Huber @wkhuber.bsky.social · 17/01/2026

For many years, Peer Bork organised Bio-IT retreats to bring together the bioinformaticians across EMBL, in Garmisch-Partenkirchen and later Feldberg. Days out on the mountain followed by forward-looking and meta-science oriented sessions in the hut that fueled many projects and careers.

Peer Bork on top of Zugspitze, ready to race down

Peer Bork, Jan Korbel, others at Sonnenkar ski lift at Zugspitze

Après-Ski scientific sessions from 16:00 till very late.

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 16/01/2026

I can not believe this news. The EMBL community, microbiome field and bioinformatics in general loses a legend 😢 www.embl.org/news/embl-an...

embl.org

In remembrance of Peer Bork | EMBL

EMBL and its community are deeply saddened by the death of Peer Bork, the organisation’s Interim Director General.

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 12/01/2026

I'll bee in London at the end of the month for the Festival of Genomics. Who can I run into?

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 17/12/2025

Enjoy this festive season on LinkedIn!

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 04/12/2025

Any TCR-seq folk attending Festival of Genomics in London? festivalofgenomics.com/london

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 04/12/2025

Was thinking of attending as well. Unfortunately I am in the other 10% now 😂

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 26/11/2025

Ja mijn broers zijn altijd onder de indruk dat we alles van ons gezin in die auto krijgen :)

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 26/11/2025

Fair enough! Prijs is ook wel effectief gestegen tegenover wanneer ik hem heb aangeschaft

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 26/11/2025

Ik heb deze oefening 3 jaar geleden gedaan. Ionis en Enyaq stonden ook op shortlist. Ben uiteindelijk bij Polestar 2 uitgekomen wegens leverbaarheid en betere prijs. Enorm tevreden van! Wil uw lijstje niet terug openbreken maar is er een reden waarom die er niet tussen staat?

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/11/2025

Cool! Congrats on getting those papers out!

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/11/2025

Zou dat in Galatasaray zijn gebeurd die stuntzege?

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 24/11/2025

Finding the putative target of a TCR is hard! But I am really excited to see that innovative cancer therapy companies like Obsidian Therapeutics are getting some real value out of using our database + machine learning algorithm.

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 11/11/2025

That's a very nice way of putting it :)

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 28/10/2025

Crazy excited about Jack White being on tour again! He was just announced headlining Best Kept Secret festival in the NL 🥳

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 28/10/2025

Among many things, in this episode we discuss: - Obsidian's lead program, OBX-115, a modified TIL cell therapy - The critical role of TCR sequencing in profiling infusion products, tracking clonotypes, and identifying biomarkers for therapy response. Listen/View here: youtu.be/J41q0fUqeVo?...

youtu.be

The Repertoire Room: Episode 3 - Arman Aksoy (Obsidian Therapeutics)

YouTube video by ImmuneWatch

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 28/10/2025

Episode 3 of “The Repertoire Room” has just been released! After 2 episodes with technology providers in the TCR sequencing space, I now wanted to have a conversation with someone that was really using these technologies to push innovative therapies to patients. Enter: @armanaksoy.bsky.social

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 27/10/2025

Oh great! And why? Because of the relative smaller size compared to ESMO?

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 27/10/2025

This might end up in the void, but is ESMO IO worth attending?

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 03/10/2025

Vooral dus een anekdotische les gebaseerd op eigen ervaring:)

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 03/10/2025

2) Solving a scientific problem does not equal market opportunities. Bv. ImmuneWatch. Sterke tech maar lang zoeken naar product-market fit. Na eerst diagnostiek te exploreren lijken we die gevonden te hebben met software/service model. 3) Lijst van frameworks die mij goed hebben geholpen

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 03/10/2025

Is het not done om hier naar Linkedin te linken?🤔 Heb daar even drie take aways uitgeschreven: 1) Stay Flexible Bv. Kultured: Succesvolle Krautfunding en initiele B2C verkoop maar verdere groei viel tegen. Pivot naar B2B lijkt way to go.

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 03/10/2025

If you asked me 10 years ago, I wouldn't have guessed that I would ever give a guest lecture on "Innovation and Entrepreneurship" Talks about microbiology, sequencing technologies, gene editing technologies, fermentation or bioinformatics: yes. But Entrepreneurship, nah :)

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Jenna Avery @jennaavery.bsky.social · 02/10/2025

Tonight at a public meeting I clapped when everyone else was murmuring in fear and worry about the idea of reducing the number of lanes on a road in order to accommodate wider sidewalks and bike lanes. Definitely an outlier.

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 01/10/2025

OMG 😭 How could I have missed this

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 25/09/2025

Always curious whether this new update will bring new insights for you!

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 17/09/2025

Lol, indeed not something everyone can say 😃

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Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 17/09/2025

Episode 2 of my podcast, the Repertoire Room is live! In this podcast I hope to have insightful conversations with people working on TCR sequencing and analysis. Now I sat down with the developer of one of the most used tools in the field: MiXCR www.immunewatch.com/news/podcast...

immunewatch.com

Podcast: The Repertoire Room - Episode 2 featuring Stanislav Poslavsky (MiLaboratories)

Sander Wuyts, PhD 🧬 @swuyts.bsky.social · 16/09/2025

Never thought I was going to post something like this on our Slack but after submitting some EU-grants it felt like the right thing to do 😂