Now out in
@science.org ! What gives some colorectal cancer (CRC) cells the ability to spread? We found that ceramides made by CRC cancer cells help activate a reparative program to metastasize. www.science.org/doi/10.1126/...
science.org
Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program
Mechanisms by which primary tumor cells acquire metastatic capability through metabolic and signaling adaptations are currently poorly understood. We demonstrate that tumor-intrinsic ceramide metaboli...
