iiinova — where your digital self keeps evolving

Reposted by Sunil Kumar Pradhan

FragileNucleosome @fnucleosome.bsky.social · 17/06/2026

We just started our summer break, but we're also planning our September-December seminar schedule! If you have an exciting chromatin/transcription story that will be ready for the spotlight by then, use the survey below to nominate yourself to give a #FNucleosome talk 🧬🧬 forms.gle/1EKYN2Nt79ar...

forms.gle

Application to speak in the Fragile Nucleosome series

Thank you for your interest in our seminar series! We use a variety of different session formats but, in general, trainees can plan for a ~15 min talk + 5min Q/A and PIs can plan for a ~25min talk +...

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Reposted by Sunil Kumar Pradhan

Cardoso lab @cardosolab.bsky.social · 11/06/2026

New review in NAR! We connect the two halves of the DNA replication field — single-cell microscopy and genome-wide sequencing to show how each method’s strengths build one picture: from DNA fibers → replication foci → origin & timing maps. 🔗 doi.org/10.1093/nar/gkag550 @narjournal.bsky.social

doi.org

Spatial organization and dynamics of genome replication: from forks to foci

Abstract. Genome replication is without doubt the most complex and critical activity of all living cells. Any error may not only affect the cell itself but

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Reposted by Sunil Kumar Pradhan

FragileNucleosome @fnucleosome.bsky.social · 18/03/2026

We have another exciting #FragileNucleosome seminar for you next week! @sunil-k-pradhan.bsky.social and Genevieve Fourel will share their fascinating stories on chromatin and genome organization. Click here to register: us06web.zoom.us/webinar/regi...

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Reposted by Sunil Kumar Pradhan

The EMBO Journal @embojournal.org · 07/10/2025

New method paper: Bennie Lemmens et al @scilifelab.se describe 3D-SPARK, a super-resolution microscopy method that maps changes in DNA replication nanostructures in response to genetic perturbations or drugs, linking spatial cell biology with DNA synthesis dynamics www.embopress.org/doi/full/10....

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Sunil Kumar Pradhan @sunil-k-pradhan.bsky.social · 10/09/2025

Different perspectives on epigenetic dynamics and memory, especially before genome replication: We show H3K36me3 is dynamically enriched at pericentromeric heterochromatin (PCH) before its replication and erased after, tightly linking epigenetics and replication timing. doi.org/10.1038/s443...

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Reposted by Sunil Kumar Pradhan

Cardoso lab @cardosolab.bsky.social · 07/07/2025

🧬⚡Your sunscreen is only half the story We show that near-infrared light makes UV damage WORSE. nIR loosens DNA packaging, creating a repair traffic jam that increases breaks. We are ignoring the invisible majority of solar radiation that hacks DNA repair. doi.org/10.1038/s415... @tuda.bsky.social

doi.org

Exposure of cells to near-infrared irradiation relaxes chromatin compaction and facilitates recognition of cyclo-butane pyrimidine dimers - Scientific Reports

Scientific Reports - Exposure of cells to near-infrared irradiation relaxes chromatin compaction and facilitates recognition of cyclo-butane pyrimidine dimers

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Reposted by Sunil Kumar Pradhan

Cardoso lab @cardosolab.bsky.social · 14/02/2025

Warmest congratulations to Dr. Sunil K. Pradhan (@sunil-k-pradhan.bsky.social) on successfully defending his PhD thesis on genome replication and epigenetic regulation in mammalian cells! Wishing you continued success as you embark on your next chapter. 🎓"

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