Cardoso Lab, Technische Universit�t Darmstadt, Germany

When exposed to replication stress, the factors involved in DNA replication display differing responses that in many cases remain unexplained. In this study, we generated a series of genomically engin...

Abstract. Genome replication is without doubt the most complex and critical activity of all living cells. Any error may not only affect the cell itself but

Scientific Reports - Exposure of cells to near-infrared irradiation relaxes chromatin compaction and facilitates recognition of cyclo-butane pyrimidine dimers

Silencing of endogenous retroviral elements (ERVs) is mediated by KAP1. Here, the authors describe the molecular mechanism by which KAP1 induces structural reorganization and multimerization of HP1α a...