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Molecular Psychiatry - Grin2a knockout in adolescent dopamine neurons disrupts prediction error signaling and produces a phenotype relevant to schizophrenia

A new approach to magnetic resonance imaging, ‘multiplexed magnetic resonance imaging’, is reported, which enables high-resolution simultaneous multiparametric mapping of multiple molecules in standar...

Behavioral therapies for post-traumatic stress disorder are negatively affected by stress. We show that brain areas involved in stress, emotion, and extinction learning are responsible for these adve...

The Beckman Institute at the University of Illinois at Urbana-Champaign offers three postdoctoral fellow programs to support outstanding scientists: Beckman Institute Postdoctoral Fellows Program, Car...

Communications Biology - The nucleus reuniens encodes associative value in both humans and rats. In rats, it also tracks defensive freezing states. The reuniens has a conserved role across species...

How the administration is breaking the government, and what that means for all of us.

Molecular Psychiatry - Hippocampal ensembles regulate circuit-induced relapse of extinguished fear

After fear conditioning, repeated presentation of the conditioned stimulus (CS) alone produces a context-dependent extinction of learned fear. The hippocampus has a critical role in this process, but ...

Decades of research have established a critical role of the basolateral complex of the amygdala (BLA) in the encoding and storage of aversive memories. Much of this work utilizes Pavlovian fear condit...

Information for the NSF community regarding executive orders.

The ability to use subjective, latent contextual representations to influence decision-making is crucial for everyday life. The hippocampus is hypothesized to bind together otherwise abstract combinat...