iiinova — where your digital self keeps evolving

Reposted by Sophie Georgin-Lavialle

FHU INFLAMME @fhu-inflamme.bsky.social · 11/03/2026

🎬2 minutes pour comprendre l’inflammation: Épisode 1: Qu’est-ce que la FHU INFLAMME, et pourquoi existe-t-elle ? Nous vous présentons la FHU INFLAMME, une fédération hospitalo-universitaire mobilisée pour faire progresser la recherche sur l’inflammation et améliorer la prise en charge des patients.

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Reposted by Sophie Georgin-Lavialle

FHU INFLAMME @fhu-inflamme.bsky.social · 18/03/2026

🎬 La Minute de l’Inflammation – Épisode 1 : la voie NF-κB la voie NF-κB, un mécanisme clé qui déclenche l’inflammation et peut dérailler en cas de dysfonctionnement. ▶️ www.youtube.com/watch?v=-DhU... #Inflammation #Immunologie #NFkB #VulgarisationScientifique #RechercheMédicale

youtube.com

Episode n°1 : La voie NF-κB

YouTube video by FHU INFLAMME

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Reposted by Sophie Georgin-Lavialle

Thomas Henry @cinflammasome.bsky.social · 05/12/2025

Kudos to Pauline, Flora, Yvan and the #Pyrin team, and many thanks to all the collaborators notably @sophiegeorgin.bsky.social @fhu-inflamme.bsky.social, Alessandra Carbone & Marco Gattorno's teams.

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Reposted by Sophie Georgin-Lavialle

The Lancet Rheumatology @thelancetrheum.bsky.social · 05/09/2025

Mapping the infectious burden in VEXAS syndrome: a systematic review and rationale for prevention Valentine Ribier and colleagues characterise the infectious burden of VEXAS syndrome and propose preventive strategies bit.ly/3VDJIPq @terrierben.bsky.social @sophiegeorgin.bsky.social

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Reposted by Sophie Georgin-Lavialle

Journal of Experimental Medicine @jem.org · 15/04/2025

Review: Spaan, Boisson, and @sethlucianmasters.bsky.social review the known primary disorders of the polyubiquitination pathways in humans that lead to #autoinflammation and/or #immunodeficiency rupress.org/jem/article/...

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Reposted by Sophie Georgin-Lavialle

Marie-Louise Frémond @mlfremond.bsky.social · 12/04/2025

😃 J-6 avant la tenue de l’édition 2025 des MIPs 🗓️ Vendredi 18 avril 2025 à l’institut Imagine à Paris ! La journée sera accessible en présentiel et en distanciel. 👉 Prolongation des inscriptions jusqu’à lundi 14 avril 12h ! 🛜 Lien d’inscription : www.eventbrite.com/e/mip-2025-t...

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TRAstonDrs @castltrastondrs.medsky.network · 21/03/2025

& pyrin-associated autoinflammation with hypereosinophilia. A section dedicated to current somatic forms of FMF is also developed. Several patients with undifferentiated systemic AIDs/syndrome of undifferentiated recurrent fever www.jaci-inpractice.org/article/S221... @jaciinpractice.bsky.social

jaci-inpractice.org

New Diseases Linked to MEFV Variants or Pyrinopathies

Autoinflammatory diseases (AIDs) are characterized by dysregulation of innate immunity, leading to systemic inflammation. Familial Mediterranean fever (FMF) is the most common AID, associated with var...

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Reposted by Sophie Georgin-Lavialle

TRAstonDrs @castltrastondrs.medsky.network · 21/03/2025

This review provides an update on AIDs associated with pathogenic variants in MEFV ( #pyrinopathies ). Those include new dominant forms (exon 10 delM694 & non-exon 10 T577, H478, P373), pyrin-associated autoinflammation - neutrophilic dermatosis, pyrin-associated autoinflammation- neuroinflammation

jaci-inpractice.org

New Diseases Linked to MEFV Variants or Pyrinopathies

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Reposted by Sophie Georgin-Lavialle

Bogunovic Lab @bogunoviclab.bsky.social · 01/01/2025

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)? Latest from us. Published today. News here www.cuimc.columbia.edu/news/what-ha... article here: www.nature.com/articles/s41... @stewart_ojay @BogunovicLab and a huge international team thank you 🙏🏼

cuimc.columbia.edu

What Happens When Some Cells Are More Dad Than Mom (and Vice Versa)?

A new study shows that some of our cells favor genes of one parent or the other and can explain a longstanding mystery of why some people with disease-causing genes experience no symptoms.

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