Diet-induced obesity (DIO) promotes the accumulation of stromal cells with senescent characteristics in the adipose tissue (AT). Selectively clearing these cells—either through chemical senolytics or ...

Objective This study aimed to evaluate the impact of socioeconomic disparities on the allocation of second-line treatments among patients with type 2 diabetes (T2D). Materials and Methods We conducte...

Suneil Koliwad (S.K.) and Martin Valdearcos (M.V.) spoke with Cell Reports about their scientific journeys leading to their recent paper investigating the role of microglia in shaping blood glucose ho...

Valdearcos et al. show that microglia shape the hypothalamic perineuronal network during early postnatal life, ensuring that hypothalamic neurons projecting to the pancreatic β cell compartment during...

Banned terms must be scrubbed from CDC-authored manuscripts

In their study of a mouse model of bone loss during lactation, Babey et al. identified a hormone, secreted by brain cells, that enhances bone mass and strength.

This Consensus Statement uses available mechanistic knowledge on pharmaceutical, chemical, physical and biological agents to identify the key characteristics (KCs) of metabolism-disrupting agents (MDA...

The fledgling social media site has been flooded with new users since the election. It hasn’t all been easy.