Reposted by WUTang Lab
Christian Gonzalez, @simonytanglab.bsky.social & co show that a chronic high-fat diet and impaired β-cell function mouse model more accurately captures the multifactorial inflammatory microenvironment of intervertebral disc degeneration induced by #Type2Diabetes #T2D
Read doi.org/10.1242/dmm....
doi.org
Degenerating intervertebral discs in the streptozotocin-high-fat diet model of type 2 diabetes show extensive inflammation
Summary: The streptozotocin-high-fat diet mouse model recapitulates the complexities of the chronic inflammatory processes in the intervertebral disc during type 2 diabetes in humans.
