Reposted by Sikander Hayat
An AI framework reduced CAR T target discovery to less than a few weeks and identified GPNMB as its top candidate. A CAR T built against it showed robust tumor-killing in mouse models of several cancers. doi.org/hb8p2j
medicalxpress.com
AI framework helps identify new targets for CAR T cell therapy
Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that centers scientists' expertise to find viable target antigens for CAR T cell therapy.