SheinerLab @sheinerlab.bsky.social · 03/08/2026We knew Toxoplasma Type I needs fats to survive in culture. Now we show this in Toxoplasma Type II, responsible for most human infections in Europe and North America. Blocking fatty acid elongation reduced growth and persistence in lab culture and in animals. www.biorxiv.org/content/10.6... 082
SheinerLab @sheinerlab.bsky.social · 13/03/2026Calling all parasite enthusiasts in and around Scotland 👇 022
SheinerLab @sheinerlab.bsky.social · 20/02/2026Care for some #toxoplasma with your beer? @colbertlateshow.bsky.social bear-poop-beer report is making toxoplasma great again 010
SheinerLab @sheinerlab.bsky.social · 05/02/2026Thank you Philippe, I had an excellent and inspiring day!! 010
SheinerLab @sheinerlab.bsky.social · 30/01/2026If you are a committed scientist who wishes to work with Toxoplasma or with organelles (or both!!) - come work with us: www.jobs.gla.ac.uk/job/research... 053
SheinerLab @sheinerlab.bsky.social · 22/12/2025Perkinsus marinus is an important marine pathogen yet we know little about its biology. @macleanlab.bsky.social reports here complexome work of whole parasite and mitochondria mapping the essential mitochondrial enzymes and kickstarting future functional studies. www.biorxiv.org/content/10.6...biorxiv.orgComplexome profile of mitochondrial complexes in the myzozoan parasite of oysters, Perkinsus marinusMitochondrial complexes, such as the mitochondrial electron transport chain (mETC), the F1Fo-ATP synthase and the mitochondrial ribosome, are centrally important for mitochondrial function. Recently, ... 0102
Reposted by SheinerLabAnthony M. Bonacolta @ambonacolta.bsky.social · 04/12/2025Had a great time interviewing Dr. Lilach Sheiner (@sheinerlab.bsky.social) for the latest edition of ISOP’s Protistology Newsletter. Check it out here! #ProtistsOnSky #Toxoplasma #Scienceyoutu.beISOP member spotlight Lilach SheinerYouTube video by Protistologists 0105
Reposted by SheinerLabRoss Waller @rosswaller.bsky.social · 28/11/2025Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified. www.biorxiv.org/content/10.1... 24618
Reposted by SheinerLabThe Geordie Parasitologist @geordieparasit.bsky.social · 21/11/2025🎓 Funded #PhD studentships in pathogen biology and parasitology *Cell and Molecular Biology*; *Host-pathogen interactions* Part of the EastBio Doctoral Landscape Award Based in the Edinburgh area of Scotland PhD 1: bit.ly/Host-pathoge... PhD 2: bit.ly/Parasite-sca... @uoe-eid.bsky.socialfindaphd.comEastBio: A host-directed approach to identify novel therapeutic targets of infectious reproductive diseases at Moredun Research Institute on FindAPhD.comPhD Project - EastBio: A host-directed approach to identify novel therapeutic targets of infectious reproductive diseases at Moredun Research Institute, listed on FindAPhD.com 166
SheinerLab @sheinerlab.bsky.social · 06/11/2025and meet the @sppirit-network.bsky.social dream team that made it all happen! Follow the for more (a new #Postdoc fellowship workshop coming up!!) 040
Reposted by SheinerLabSPPIRIT Network @sppirit-network.bsky.social · 04/11/2025Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications. Join us at 12 noon on Thursday 14th November! Register at docs.google.com/forms/d/e/1F... 045
SheinerLab @sheinerlab.bsky.social · 04/11/2025Busy and exciting poster session @sppirit-network.bsky.social conference. SheinerLab's Anil and Victor spotted checking out some cool work! 051
SheinerLab @sheinerlab.bsky.social · 04/11/2025Jana getting everyone into #membranes at @sppirit-network.bsky.social conference. 120
SheinerLab @sheinerlab.bsky.social · 07/10/2025An official new measuring unit for the parasitology community had emerged from this @parafrap.bsky.social #EMBO conference... #shitton @nicolas3474.bsky.social @kirkdeitsch.bsky.social 060
SheinerLab @sheinerlab.bsky.social · 06/10/2025Fabulous work from @nicolas3474.bsky.social on the protein atlas of the molluscs parasite #Perkinsus @parafrap.bsky.social 150
SheinerLab @sheinerlab.bsky.social · 06/10/2025Wonderful session on @parafrap.bsky.social parasites pathogenesis chaired by @apicolipid.bsky.social @clarehardinglab.bsky.social 080
SheinerLab @sheinerlab.bsky.social · 06/10/2025The science at #ParaFrap is exciting and surprising as always - less surprising: who are the last people standing on night #1 ... @freddyfrischknecht.bsky.social @kirkdeitsch.bsky.social 0130
SheinerLab @sheinerlab.bsky.social · 06/10/2025Kick-off of @parafrap.bsky.social #EMBO conference at #LesEmbiez by the wonderful organisers @gloverlab.bsky.social and Benoit Gamain who put together an exciting program about parasite biology, epidemiology and combat. 040
SheinerLab @sheinerlab.bsky.social · 30/09/2025We have a project advertised as part of the @NorthWestBio1 program this year - come join us! www.gla.ac.uk/postgraduate... Applications to the program are here: www.gla.ac.uk/postgraduate...gla.ac.ukUniversity of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Lilach Sheiner 000
SheinerLab @sheinerlab.bsky.social · 18/09/2025Calling all mitochondria enthusiasts, we are recruiting for a new project (and the post will be split between Glasgow and Helsinki) www.jobs.gla.ac.uk/job/research...jobs.gla.ac.ukResearch AssociateJob PurposeThe purpose of this role is to carry out cutting-edge research to understand the structure and function of complexes essential for organelle biology and function in the apicomplexan para... 044
Reposted by SheinerLabAndré Schneider, University of Bern @schneian.bsky.social · 10/09/2025The trypanosomal TAC is required for mitochondrial DNA segregation. We provide insight into TAC assembly: one of the most extreme sorting event for any mitochondrion. Congratulations to Philip, Salome and Bernd #mitochondria #mtDNA #Trypanosoma journals.plos.org/plospathogen...journals.plos.orgAssembly of the mitochondrial outer membrane module of the trypanosomal tripartite attachment complexAuthor summary Mitochondria are essential for nearly all eukaryotes. This requires proper segregation of the organelles and their genomes to the daughter cells during cell division. For Trypanosomes a... 0102
SheinerLab @sheinerlab.bsky.social · 26/06/2025Our session explored how studying bioenergetics enzymes via structural biology in divergent protist sheds light on the role of these enzymes and their assemblies across eukaryotes and on how they function in the context of each organisms’ specialised needs. 000
SheinerLab @sheinerlab.bsky.social · 24/06/2025Team bioenergetics in divergent organisms is ready to go! #ICOP25 @macleanlab.bsky.social @lettsscience.bsky.social 111
SheinerLab @sheinerlab.bsky.social · 24/06/2025@fad1.bsky.social showing us how gene drives will end malaria!! 000
SheinerLab @sheinerlab.bsky.social · 24/06/2025A first #ICOP25 day 2 highlight: Dayana Salas-Leiva of Ross Waller's lab uses LOPIT to ask not only what makes a symbiotic relationship, but what baggage is left after a break-up. Stay tuned! 030
SheinerLab @sheinerlab.bsky.social · 23/06/2025Some great models used to study endosymbiosis and what does it take to make a stable relationship: Julius Lukes LOPIT of Insect Trypanosomes reveals new host-endosymbiont interactions Ellen Yeh Epithemia diatoms probes the underlying mechanisms of establishing endosymbiosis 020
SheinerLab @sheinerlab.bsky.social · 23/06/2025First - a vivid discussion about determining the origin and early evolution of eukaryotes following Andrew Roger's talk. 130
SheinerLab @sheinerlab.bsky.social · 23/06/2025#ICOP25 opened today with so many exciting eukaryotic microbe insights 🦠 - you know its gonna be a great one when it starts with a drown video 😉 Stay tuned!! 360
Reposted by SheinerLabShikha @shikhas.bsky.social · 19/05/2025Happy to have contributed to this wonderful study about #Toxoplasma #supercomplex led by @macleanlab.bsky.social, @sheinerlab.bsky.social and Alex Mühleip. Parasite mitochondria never cease to amaze! Please go checkout 👇 072
Reposted by SheinerLabAndrew Maclean @macleanlab.bsky.social · 19/05/2025Happy to share our latest paper. Result of a great collaboration between @sheinerlab.bsky.social @oninopantsu.bsky.social and Alexander Mühleip’s new group. www.nature.com/articles/s41...nature.comStructure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex - Nature Structural & Molecular BiologyHere the authors demonstrate that the assembly of mitochondrial respiratory supercomplex (III2–IV) from Toxoplasma gondii is critical for parasite fitness. They reveal the basis for cytochrome b inhib... 43712
SheinerLab @sheinerlab.bsky.social · 19/05/2025Other complex III inhibitors are being developed as drug leads for apicomplexan diseases. Together with Stone Doggett and colleagues at @OHSUNewswe we showed how the drug-lead ELQ-300 binds Toxoplasma complex III and designed a more potent version. 000
SheinerLab @sheinerlab.bsky.social · 19/05/2025Atovaquone is a clinically used drug for apicomplexan diseases such as #malaria and #toxoplasmosis, but its precise mechanism of inhibition was unknown. We showed how atovaquone interacts with Toxoplasma complex III and why it is selective to apicomplexan compared to human. 000
SheinerLab @sheinerlab.bsky.social · 19/05/2025Respiratory complexes form “super-complexes” whose physiological function is debated, and assembly only studied in a few organisms. We showed that apicomplexan conserved proteins mediate III2-IV supercomplex formation, and that this provides competitive growth advantage. 000
SheinerLab @sheinerlab.bsky.social · 19/05/2025Parasites need mitochondrial respiration to infect and spread. Effective anti-malaria and ani-toxoplasmosis drugs target respiratory complexes (e.g. atovaquone)! But how do the parasite complexes work and how do drugs inhibit them? Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇 3146
SheinerLab @sheinerlab.bsky.social · 25/04/2025Inspirational talk from Dr Sharifa Abdulla about how to strike partnerships - think: What is the problem Whose problem is it (and therefore) Who should be engaged in the partnership 000
SheinerLab @sheinerlab.bsky.social · 25/04/2025Excellent to take part in a round table focus on African partnerships within our Glasgow Changing Futures strategy @uofgsii.bsky.social @uofglasgow.bsky.social 111
SheinerLab @sheinerlab.bsky.social · 31/03/2025As Sheinerlab is joining the trend, Chat seem to have known that @macleanlab.bsky.social started his own lab recently and took the executive decision to remove him from the photo 😲😆 052
SheinerLab @sheinerlab.bsky.social · 29/03/2025We will inform the hotel you liked it 😉 Thank you so much for visiting us it was a great treat as always! 010
SheinerLab @sheinerlab.bsky.social · 18/03/2025A true honour. Thank you to BSP @bspparasitology.bsky.social and our fabulous parasitology community 2182
Reposted by SheinerLabLSHTM Malaria Centre @lshtm-malaria.bsky.social · 17/03/2025Interested in how genomics, transcriptomics & more shape infectious disease research? Join the @lshtm.bsky.social Infectious Disease -Omics short course starting 17 June 2024 to explore cutting-edge techniques & their real-world applications! Apply now 👉 bit.ly/4kJOoPo 023
Reposted by SheinerLabEmma Marie Briggs @emmamariebriggs.bsky.social · 17/03/2025Funded PhD project with myself, Prof. Paul Denny at Durham University and Dr Kalesh Karunakaran at Teeside University now open for applications! www.findaphd.com/phds/project...findaphd.comUncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University on FindAPhD.comPhD Project - Uncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University, listed on FindAPhD.com 087
Reposted by SheinerLabSiegel Lab @siegel-lab.bsky.social · 12/03/2025If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next. Our manuscript, just published in Nature, provides some answers! www.nature.com/articles/s41... @lmumuenchen.bsky.social @erc.europa.eu a.eu @nature.com 23712
Reposted by SheinerLabPerona Lab, Edinburgh, UK @peronalab.bsky.social · 03/03/2025I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open. 16356
SheinerLab @sheinerlab.bsky.social · 28/02/2025🔊 Calling all parasite enthusiasts - come join us to study Toxoplasma and Plasmodium organelle biology 🔬 www.jobs.gla.ac.uk/job/research...jobs.gla.ac.ukResearch AssociateResearch Associate COLLEGE OF MEDICAL VETERINARY & LIFE SCIENCES SCHOOL OF INFECTION AND IMMUNITY Grade 7We are seeking to recruit an experienced Research Associate/postdoctoral researcher to ... 01310
SheinerLab @sheinerlab.bsky.social · 27/02/2025What a proud moment to see @macleanlab.bsky.social starting his own lab in a few days 🤩 For all of you #ECRs out there thinking who should you work with in your next career stage - contact Andrew think no more! 2201
SheinerLab @sheinerlab.bsky.social · 26/02/2025Exciting brainstorming meeting to discuss #emergingchallenges in #Parasitology 💭🎓 Always a fertile & inspirational discussion with @wellcometrust.bsky.social folks in the room 🤩 071
Reposted by SheinerLabEmma Wilson @toxobrains.bsky.social · 18/02/2025Sorry we got blown off by the storm last time but looking forward to going back to Glasgow and talking parasites and brains with an inspiring set of scientists @abhinay.bsky.social @clarehardinglab.bsky.social @maizel-lab.org @sheinerlab.bsky.social 062
Reposted by SheinerLabParasitesRule @parasitesrule.org · 05/02/2025Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website. www.parasitesrule.com/mpm-xxxvi/tr...parasitesrule.comMolecular Parasitology Community - Travelaward2025Scroll down for the application form 01313
SheinerLab @sheinerlab.bsky.social · 07/02/2025The only thing that can get more exiting than @sloanmegan.bsky.social @clarehardinglab.bsky.social work about #iron metabolism in #toxoplasma is a scientific explanation that includes Adam Driver! 010