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SheinerLab

@sheinerlab.bsky.social
288 followers 81 following 58 posts

Research lab interested in #parasites #apicomplexa #toxoplasma #toxoplasmosis #plasmodium #malaria #mitochondria #cell-biology lilachsheiner.wixsite.com/sheinerla…

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SheinerLab @sheinerlab.bsky.social · 03/08/2026
We knew Toxoplasma Type I needs fats to survive in culture. Now we show this in Toxoplasma Type II, responsible for most human infections in Europe and North America. Blocking fatty acid elongation reduced growth and persistence in lab culture and in animals. www.biorxiv.org/content/10.6...
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SheinerLab @sheinerlab.bsky.social · 13/03/2026
Calling all parasite enthusiasts in and around Scotland 👇
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SheinerLab @sheinerlab.bsky.social · 20/02/2026
Care for some #toxoplasma with your beer? @colbertlateshow.bsky.social bear-poop-beer report is making toxoplasma great again
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SheinerLab @sheinerlab.bsky.social · 05/02/2026
Thank you Philippe, I had an excellent and inspiring day!!
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SheinerLab @sheinerlab.bsky.social · 30/01/2026
If you are a committed scientist who wishes to work with Toxoplasma or with organelles (or both!!) - come work with us: www.jobs.gla.ac.uk/job/research...
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SheinerLab @sheinerlab.bsky.social · 22/12/2025
Perkinsus marinus is an important marine pathogen yet we know little about its biology. @macleanlab.bsky.social reports here complexome work of whole parasite and mitochondria mapping the essential mitochondrial enzymes and kickstarting future functional studies. www.biorxiv.org/content/10.6...
biorxiv.org
Complexome profile of mitochondrial complexes in the myzozoan parasite of oysters, Perkinsus marinus
Mitochondrial complexes, such as the mitochondrial electron transport chain (mETC), the F1Fo-ATP synthase and the mitochondrial ribosome, are centrally important for mitochondrial function. Recently, ...
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Anthony M. Bonacolta @ambonacolta.bsky.social · 04/12/2025
Had a great time interviewing Dr. Lilach Sheiner (@sheinerlab.bsky.social) for the latest edition of ISOP’s Protistology Newsletter. Check it out here! #ProtistsOnSky #Toxoplasma #Science
youtu.be
ISOP member spotlight Lilach Sheiner
YouTube video by Protistologists
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Ross Waller @rosswaller.bsky.social · 28/11/2025
Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified. www.biorxiv.org/content/10.1...
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The Geordie Parasitologist @geordieparasit.bsky.social · 21/11/2025
🎓 Funded #PhD studentships in pathogen biology and parasitology *Cell and Molecular Biology*; *Host-pathogen interactions* Part of the EastBio Doctoral Landscape Award Based in the Edinburgh area of Scotland PhD 1: bit.ly/Host-pathoge... PhD 2: bit.ly/Parasite-sca... @uoe-eid.bsky.social
findaphd.com
EastBio: A host-directed approach to identify novel therapeutic targets of infectious reproductive diseases at Moredun Research Institute on FindAPhD.com
PhD Project - EastBio: A host-directed approach to identify novel therapeutic targets of infectious reproductive diseases at Moredun Research Institute, listed on FindAPhD.com
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SheinerLab @sheinerlab.bsky.social · 06/11/2025
and meet the @sppirit-network.bsky.social dream team that made it all happen! Follow the for more (a new #Postdoc fellowship workshop coming up!!)
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SPPIRIT Network @sppirit-network.bsky.social · 04/11/2025
Coming up: Postdoctoral fellowship mini-workshop as a part of the SPPIRIT Forum series. EMBO, Marie Curie, and Wellcome Early Career fellows will share their advice on fellowship applications. Join us at 12 noon on Thursday 14th November! Register at docs.google.com/forms/d/e/1F...
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SheinerLab @sheinerlab.bsky.social · 04/11/2025
Busy and exciting poster session @sppirit-network.bsky.social conference. SheinerLab's Anil and Victor spotted checking out some cool work!
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SheinerLab @sheinerlab.bsky.social · 04/11/2025
Jana getting everyone into #membranes at @sppirit-network.bsky.social conference.
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SheinerLab @sheinerlab.bsky.social · 07/10/2025
An official new measuring unit for the parasitology community had emerged from this @parafrap.bsky.social #EMBO conference... #shitton @nicolas3474.bsky.social @kirkdeitsch.bsky.social
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SheinerLab @sheinerlab.bsky.social · 06/10/2025
Fabulous work from @nicolas3474.bsky.social on the protein atlas of the molluscs parasite #Perkinsus @parafrap.bsky.social
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SheinerLab @sheinerlab.bsky.social · 06/10/2025
Wonderful session on @parafrap.bsky.social parasites pathogenesis chaired by @apicolipid.bsky.social @clarehardinglab.bsky.social
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SheinerLab @sheinerlab.bsky.social · 06/10/2025
The science at #ParaFrap is exciting and surprising as always - less surprising: who are the last people standing on night #1 ... @freddyfrischknecht.bsky.social @kirkdeitsch.bsky.social
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SheinerLab @sheinerlab.bsky.social · 06/10/2025
Kick-off of @parafrap.bsky.social #EMBO conference at #LesEmbiez by the wonderful organisers @gloverlab.bsky.social and Benoit Gamain who put together an exciting program about parasite biology, epidemiology and combat.
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SheinerLab @sheinerlab.bsky.social · 30/09/2025
We have a project advertised as part of the @NorthWestBio1 program this year - come join us! www.gla.ac.uk/postgraduate... Applications to the program are here: www.gla.ac.uk/postgraduate...
gla.ac.uk
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Lilach Sheiner
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SheinerLab @sheinerlab.bsky.social · 25/09/2025
Congratulations Saniya for graduating her PhD!!!
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SheinerLab @sheinerlab.bsky.social · 18/09/2025
Calling all mitochondria enthusiasts, we are recruiting for a new project (and the post will be split between Glasgow and Helsinki) www.jobs.gla.ac.uk/job/research...
jobs.gla.ac.uk
Research Associate
Job PurposeThe purpose of this role is to carry out cutting-edge research to understand the structure and function of complexes essential for organelle biology and function in the apicomplexan para...
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André Schneider, University of Bern @schneian.bsky.social · 10/09/2025
The trypanosomal TAC is required for mitochondrial DNA segregation. We provide insight into TAC assembly: one of the most extreme sorting event for any mitochondrion. Congratulations to Philip, Salome and Bernd #mitochondria #mtDNA #Trypanosoma journals.plos.org/plospathogen...
journals.plos.org
Assembly of the mitochondrial outer membrane module of the trypanosomal tripartite attachment complex
Author summary Mitochondria are essential for nearly all eukaryotes. This requires proper segregation of the organelles and their genomes to the daughter cells during cell division. For Trypanosomes a...
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SheinerLab @sheinerlab.bsky.social · 26/06/2025
Our session explored how studying bioenergetics enzymes via structural biology in divergent protist sheds light on the role of these enzymes and their assemblies across eukaryotes and on how they function in the context of each organisms’ specialised needs.
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SheinerLab @sheinerlab.bsky.social · 24/06/2025
Team bioenergetics in divergent organisms is ready to go! #ICOP25 @macleanlab.bsky.social @lettsscience.bsky.social
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SheinerLab @sheinerlab.bsky.social · 24/06/2025
@fad1.bsky.social showing us how gene drives will end malaria!!
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SheinerLab @sheinerlab.bsky.social · 24/06/2025
A first #ICOP25 day 2 highlight: Dayana Salas-Leiva of Ross Waller's lab uses LOPIT to ask not only what makes a symbiotic relationship, but what baggage is left after a break-up. Stay tuned!
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SheinerLab @sheinerlab.bsky.social · 23/06/2025
Some great models used to study endosymbiosis and what does it take to make a stable relationship: Julius Lukes LOPIT of Insect Trypanosomes reveals new host-endosymbiont interactions Ellen Yeh Epithemia diatoms probes the underlying mechanisms of establishing endosymbiosis
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SheinerLab @sheinerlab.bsky.social · 23/06/2025
First - a vivid discussion about determining the origin and early evolution of eukaryotes following Andrew Roger's talk.
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SheinerLab @sheinerlab.bsky.social · 23/06/2025
#ICOP25 opened today with so many exciting eukaryotic microbe insights 🦠 - you know its gonna be a great one when it starts with a drown video 😉 Stay tuned!!
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Shikha @shikhas.bsky.social · 19/05/2025
Happy to have contributed to this wonderful study about #Toxoplasma #supercomplex led by @macleanlab.bsky.social, @sheinerlab.bsky.social and Alex Mühleip. Parasite mitochondria never cease to amaze! Please go checkout 👇
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Andrew Maclean @macleanlab.bsky.social · 19/05/2025
Happy to share our latest paper. Result of a great collaboration between @sheinerlab.bsky.social @oninopantsu.bsky.social and Alexander Mühleip’s new group. www.nature.com/articles/s41...
nature.com
Structure, assembly and inhibition of the Toxoplasma gondii respiratory chain supercomplex - Nature Structural & Molecular Biology
Here the authors demonstrate that the assembly of mitochondrial respiratory supercomplex (III2–IV) from Toxoplasma gondii is critical for parasite fitness. They reveal the basis for cytochrome b inhib...
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SheinerLab @sheinerlab.bsky.social · 19/05/2025
Other complex III inhibitors are being developed as drug leads for apicomplexan diseases. Together with Stone Doggett and colleagues at @OHSUNewswe we showed how the drug-lead ELQ-300 binds Toxoplasma complex III and designed a more potent version.
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SheinerLab @sheinerlab.bsky.social · 19/05/2025
Atovaquone is a clinically used drug for apicomplexan diseases such as #malaria and #toxoplasmosis, but its precise mechanism of inhibition was unknown. We showed how atovaquone interacts with Toxoplasma complex III and why it is selective to apicomplexan compared to human.
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SheinerLab @sheinerlab.bsky.social · 19/05/2025
Respiratory complexes form “super-complexes” whose physiological function is debated, and assembly only studied in a few organisms. We showed that apicomplexan conserved proteins mediate III2-IV supercomplex formation, and that this provides competitive growth advantage.
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SheinerLab @sheinerlab.bsky.social · 19/05/2025
Parasites need mitochondrial respiration to infect and spread. Effective anti-malaria and ani-toxoplasmosis drugs target respiratory complexes (e.g. atovaquone)! But how do the parasite complexes work and how do drugs inhibit them? Read Andrew Maclean and Alex Mühleip phenomenal work on this! 👇
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SheinerLab @sheinerlab.bsky.social · 25/04/2025
Inspirational talk from Dr Sharifa Abdulla about how to strike partnerships - think: What is the problem Whose problem is it (and therefore) Who should be engaged in the partnership
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SheinerLab @sheinerlab.bsky.social · 25/04/2025
Excellent to take part in a round table focus on African partnerships within our Glasgow Changing Futures strategy @uofgsii.bsky.social @uofglasgow.bsky.social
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SheinerLab @sheinerlab.bsky.social · 31/03/2025
As Sheinerlab is joining the trend, Chat seem to have known that @macleanlab.bsky.social started his own lab recently and took the executive decision to remove him from the photo 😲😆
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SheinerLab @sheinerlab.bsky.social · 29/03/2025
We will inform the hotel you liked it 😉 Thank you so much for visiting us it was a great treat as always!
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SheinerLab @sheinerlab.bsky.social · 18/03/2025
A true honour. Thank you to BSP @bspparasitology.bsky.social and our fabulous parasitology community
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LSHTM Malaria Centre @lshtm-malaria.bsky.social · 17/03/2025
Interested in how genomics, transcriptomics & more shape infectious disease research? Join the @lshtm.bsky.social Infectious Disease -Omics short course starting 17 June 2024 to explore cutting-edge techniques & their real-world applications! Apply now 👉 bit.ly/4kJOoPo
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Emma Marie Briggs @emmamariebriggs.bsky.social · 17/03/2025
Funded PhD project with myself, Prof. Paul Denny at Durham University and Dr Kalesh Karunakaran at Teeside University now open for applications! www.findaphd.com/phds/project...
findaphd.com
Uncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University on FindAPhD.com
PhD Project - Uncovering the adaptation mechanism that generate dormant forms of Leishmania microbes with omics approaches at Newcastle University, listed on FindAPhD.com
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Siegel Lab @siegel-lab.bsky.social · 12/03/2025
If you are interested in antigenic variation, you may have wondered how parasites ‘select’ which antigen to express next. Our manuscript, just published in Nature, provides some answers! www.nature.com/articles/s41... @lmumuenchen.bsky.social @erc.europa.eu a.eu @nature.com
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Perona Lab, Edinburgh, UK @peronalab.bsky.social · 03/03/2025
I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.
We're based in the Ashworth Laboratories, King's Buildings, University of Edinburgh. Photo shows the main staircase in the entrance to the Ashworth, stone steps from the 1920s, decorated with a series of bright, colurful banners depicting the science that's tackled in the building.
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SheinerLab @sheinerlab.bsky.social · 28/02/2025
🔊 Calling all parasite enthusiasts - come join us to study Toxoplasma and Plasmodium organelle biology 🔬 www.jobs.gla.ac.uk/job/research...
jobs.gla.ac.uk
Research Associate
Research Associate COLLEGE OF MEDICAL VETERINARY & LIFE SCIENCES SCHOOL OF INFECTION AND IMMUNITY  Grade 7We are seeking to recruit an experienced Research Associate/postdoctoral researcher to ...
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SheinerLab @sheinerlab.bsky.social · 27/02/2025
What a proud moment to see @macleanlab.bsky.social starting his own lab in a few days 🤩 For all of you #ECRs out there thinking who should you work with in your next career stage - contact Andrew think no more!
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SheinerLab @sheinerlab.bsky.social · 26/02/2025
Exciting brainstorming meeting to discuss #emergingchallenges in #Parasitology 💭🎓 Always a fertile & inspirational discussion with @wellcometrust.bsky.social folks in the room 🤩
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Emma Wilson @toxobrains.bsky.social · 18/02/2025
Sorry we got blown off by the storm last time but looking forward to going back to Glasgow and talking parasites and brains with an inspiring set of scientists @abhinay.bsky.social @clarehardinglab.bsky.social @maizel-lab.org @sheinerlab.bsky.social
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ParasitesRule @parasitesrule.org · 05/02/2025
Do you work on parasites and reside in an LMIC? Consider applying for a 2025 MPM LMIC award. The deadline is March 3rd, 2025—details on the website. www.parasitesrule.com/mpm-xxxvi/tr...
parasitesrule.com
Molecular Parasitology Community - Travelaward2025
Scroll down for the application form
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SheinerLab @sheinerlab.bsky.social · 07/02/2025
The only thing that can get more exiting than @sloanmegan.bsky.social @clarehardinglab.bsky.social work about #iron metabolism in #toxoplasma is a scientific explanation that includes Adam Driver!
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