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Synaptophilia

@shababhannan.bsky.social
326 followers 959 following 8 posts

Neuroscientist working on fruit flies, husband+pet dad full time, by night a chef mixing flavors, Liverpool football fan on weekends. I think about Alzheimer’s disease, synapses, mitochondria, lysosomes and ER. Views are mine Baylor College of Medicine

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Synaptophilia @shababhannan.bsky.social · 22/07/2026
A striking study linking actin dysfunction to mitochondrial damage, excess glutamate signaling, and seizures—revealing how combinations of genetic variants may drive unexplained epilepsy. www.jci.org/articles/vie...
jci.org
JCI - Epilepsy-associated digenic variants affecting an actin–mitochondria–glutamate pathway promote seizure susceptibility
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Synaptophilia @shababhannan.bsky.social · 17/08/2025
We studied 100 fly orthologs of Alzheimer’s risk genes and found several crucial for CNS structure, function, or stress resilience and some also affecting Aβ and tau toxicity. www.biorxiv.org/content/10.1... #Alzheimer's #Drosophila #brain #neurons What gene would you follow up on from our results?
biorxiv.org
Revealing the nervous system requirements of Alzheimer’s disease risk genes in Drosophila
Most Alzheimer’s disease (AD) susceptibility genes have poorly understood roles in the central nervous system (CNS). To address this gap, we systematically characterized 100 conserved candidate AD ris...
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FlyBase @flybase.bsky.social · 25/06/2025
MassLive.com recently interviewed several Harvard FlyBase people and wrote this news article about the importance of FlyBase: tinyurl.com/4chpts9f
tinyurl.com
Why a database of bug genes could be one of Trump’s most devastating cuts at Harvard
FlyBase, the world's only fruit fly database, is in the crosshairs of Trump's attack on Harvard. Here's why it could matter for your health.
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Shefali @iamshef.bsky.social · 09/07/2025
Hey #Drosophila folks - its #fivedays to go to sign up as #FlyCROSS #mentor 👀 If you're faculty/postdoc/ equivalent in any scientific career & have #Drosophila research experience - fill up the mentor survey by July 14 to empower #earlycareer scientists in #Dros #community! @flybase.bsky.social
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Synaptophilia @shababhannan.bsky.social · 09/04/2025
Check out our new paper on #rare_neurological_diseases #undiagnosed_disease_network #Spinocerebellar_ataxias Our paper on RAB3A published in journal #brain shows a potential novel role for the gene in the context of rare neurological diseases. academic.oup.com/brain/advanc...
academic.oup.com
Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism
Using an untargeted computational genetic association approach and classical linkage analysis, Hengel et al. identify RAB3A as a gene linked to autosomal d
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Synaptophilia @shababhannan.bsky.social · 30/01/2025
Paper alert. We highlight some recent papers published in our special research edition on mitochondria and neuro-developmental+degenerative diseases at Frontiers. #Mitochondria #Neurodegenerative_diseases #Frontiers_in_Neuroscience www.frontiersin.org/articles/10....
frontiersin.org
Frontiers | Editorial: Molecular and cellular pathways leading to mitochondrial dysfunction and neurodegeneration: lessons from in vivo models, volume II
The second volume of our editorial is a continuation of the first (Hannan et al., 2022) and features two reviews and three research articles that highlight h...
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Loïc A. Royer 💻🔬🧪 @loicaroyer.bsky.social · 10/12/2024
Another video of a developping drosophila embryo, but this time rotating. I beleive tjis was generated in Python using @maweigert.bsky.social 's spimagine rendering tool. www.nature.com/articles/nbt... 🧪🔬🪰💻
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Zila Martinez-Lozada @zilamartinezlozada.bsky.social · 13/12/2024
My mom got polio a couple of months before the vaccine got to Mexico. She passed her teenage years in bed and was only able to walk again for the uncountable hours her grandma spent giving her therapy. #vaccinesSafeLives
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Ardem Patapoutian @ardemp.bskyverified.social · 09/12/2024
I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...
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Martin Kampmann @kampmann.bsky.social · 06/12/2024
Implementation and validation of single-cell genomics experiments in neuroscience - a consensus paper. Excited to contribute perturbation-based approaches. www.nature.com/articles/s41...
nature.com
Implementation and validation of single-cell genomics experiments in neuroscience - Nature Neuroscience
Single-cell or single-nucleus RNA-sequencing experiments form a basis for biological insights about cell types and states, but they require orthogonal experiments to confirm the functional relevance o...
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Christophe 🔬 Leterrier @christlet.bsky.social · 04/12/2024
New review: together with PhD student Ciarán Butler-Hallissey, we provide a comprehensive overview on how super-resolution microscopy can dissect the neuronal cytoskeleton, and the exciting perspectives ahead. Shock full of beautiful images, published or from our lab! www.nature.com/articles/s44...
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Synaptophilia @shababhannan.bsky.social · 27/11/2024
Recently saw this while preparing some teaching material on the #History_of_Neuroscience. This is special. Here #Cajal is sharing his reaction after seeing neurons stained with the #Golgi_stain. #Cajal_and_Golgi had conflicting views about the structure of the neurons.
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Drosophila Genomics Resource Center @dgrc.bsky.social · 23/11/2024
Hello, Drosophila Community! We’re excited to join Bluesky and connect with researchers! At the Drosophila Genomics Resource Center (DGRC), we provide reagents to power your discoveries. Follow us for updates, tips, and discussions. What’s your favorite #Drosophila research question? Let’s chat!
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Synaptophilia @shababhannan.bsky.social · 26/11/2024
Hello #Drosophila scientists in Bluesky! Here’s a list of useful #Drosophila_resources #Drosophila_starterpack I will keep sharing new resources as I find them! bsky.app/profile/bdsc... bsky.app/profile/flyb... bsky.app/profile/dgrc... bsky.app/profile/fly-... bsky.app/profile/dros...
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Coleman Lab @colemanlab.bsky.social · 25/11/2024
This week in Science Without Anguish: Who is driving our bus? The importance of controlling the controllables in research life. www.sciencewithoutanguish.com/blog/who-is-...
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Astrocyte Cafe @astrocytecafe.bsky.social · 22/11/2024
Hi #astrocyte lovers! We are organizing the third edition of #AstrocyteCafe online, with FREE monthly seminars starting from January 2025...and we are looking for speakers! Speakers can be of any career stage: just send us an email with your topic to astrocytecafe@gmail.com 😍
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Dementia Researcher @dementiaresearcher.bsky.social · 25/11/2024
🧠 The NIA seeks your input on its draft Strategic Directions for Research 2026-2030! Shape the future of ageing research by sharing your feedback by 31 Jan 2025. Learn more and contribute: www.dementiaresearcher.nihr.ac.uk/nia-strategi...
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Alt National Park Service @altnps.bsky.social · 25/11/2024
It’s disheartening to witness such short-sightedness from some…
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Synaptophilia @shababhannan.bsky.social · 25/11/2024
If you are a Neuroscience faculty teaching undergraduates, this may be a useful resource: www.funfaculty.org
funfaculty.org
Faculty for Undergraduate Neuroscience
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Namnezia 🥑 @namnezia.bsky.social · 20/11/2024
Do you teach neuroscience? Here’s a list I’ve compiled of mostly free online neuroscience textbooks, simulations and datasets you can use for your course! If I’m missing something, let me know so I can add it! docs.google.com/document/d/1...
docs.google.com
Free Neuroscience Textbooks and Online Tutorials
Free Neuroscience Textbooks and Online Tutorials (Compiled by Carlos Aizenman, Brown University, Dept. of Neuroscience) Maintaining a current list of digital educational resources is tricky. Softwar...
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Nico Schuck @nicoschuck.bsky.social · 24/11/2024
Looking for a PhD in Cognitive Science, Cognitive Neuroscience or related in Germany? One week left to apply for the Max Planck School of Cognition: cognition.maxplanckschools.org/en/application #PsychSciSky #compneurosky #neuroskyence #NeuroAI #Neuroimaging
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Cambridge Neuroscience @camneuro.bsky.social · 19/11/2024
Registration is now open for 'CNS2025: Expanding the Horizons of Brain Research' at neuroscience.cam.ac.uk/camneuro-eve... Stellar Programme w/ plenaries from Soyon Hong & Mayank Mehta & @CamNeuro peeps from 7 departments Sign up now to guarantee your space! Sorry for the silence….will do better!
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