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Sebastian Winter

@sewinter.bsky.social
1.5K followers 1.2K following 0 posts

Professor at UC Davis Health. Host-microbe and microbe-microbe interactions. Gut microbiome. Model trains. Opinions are my own.

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Reposted by Sebastian Winter
Jonathan Eisen @phylogenomics.bsky.social · 06/10/2026
CA prop 38 is a scam - vote NO. For example see: This CA proposition will send $4 billion to a single nonprofit. Who’s behind it? calmatters.org/politics/ele...
calmatters.org
Is this proposition a $4 billion giveaway to a billionaire’s LA research center?
Proposition 38 will award $4 billion to one unnamed research center. Under the very specific criteria, only one center seemingly qualifies.
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Julie Pfeiffer @jkpfeiff.bsky.social · 26/06/2026
Faculty search announcement 2026: Tenure-Track Assistant Professor in Microbiology at UT Southwestern in Dallas. We seek candidates working in microbial pathogenesis (broadly defined). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
Department members sit at a very long table in the hallway eating a pre-Thanksgiving potluck feast.
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Andreas Bäumler @abaumler.bsky.social · 16/06/2026
Is colorectal cancer driven by a disruption of anaerobiosis? A recent study by Spiga et al. makes this idea walk and talk like a duck. Read more here: www.sciencedirect.com/science/arti...
sciencedirect.com
An anaerobic pathogen rewires host metabolism to fuel oxidative growth in the inflamed gut
To colonize their host and cause disease, enteric pathogens must deploy their virulence factors to establish distinct nutrient niches. How anaerobic p…
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Fabian Rivera-Chávez @fabianrchavez.bsky.social · 09/06/2026
Now published in Cell Reports! @cellpress.bsky.social www.cell.com/cell-reports... My postdoc Dr. Maria de la Paz Gutierrez led this work showing that cholera toxin drives epithelial L-lactate production in the small intestine, creating a nutrient that Vibrio cholerae exploits during disease
cell.com
Cholera-toxin-induced disease generates epithelial-cell-derived L-lactate that promotes Vibrio cholerae growth in the small intestine
Gutierrez et al. show that cholera toxin induces epithelial LDHA-dependent L-lactate production in the small intestine, creating a nutrient niche that Vibrio cholerae exploits through LldD-mediated L-...
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Maxence Vincent @maxencevincent.bsky.social · 03/06/2026
👇👇👇 NEW PREPRINT ONLINE 👇👇👇 www.biorxiv.org/content/10.6... #NewPreprint #Microbiology #Inflammation #GutMicrobiome
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Julie Pfeiffer @jkpfeiff.bsky.social · 16/05/2026
New preprint from our collaboration with John Brooks’ lab: Viral loads can vary by more than 100-fold depending on the time of day mice are infected. And we figured out why. www.biorxiv.org/content/10.6...
biorxiv.org
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Zhu Lab at Vanderbilt University Medical Center @zhulab.bsky.social · 14/05/2026
Disease-causing pathogen rewires gut metabolism to secure nutrients for growth: Study news.vumc.org/2026/04/30/d...
news.vumc.org
Disease-causing pathogen rewires gut metabolism to secure nutrients for growth: Study
Disease-associated pathogens can actively drive intestinal inflammation by reshaping host metabolism, suggesting new therapeutic options.
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Reposted by Sebastian Winter
Judith Behnsen @judith-behnsen.bsky.social · 03/09/2025
Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.
nature.com
Commensal yeast promotes Salmonella Typhimurium virulence - Nature
Commensal Candida albicans enhances the virulence and dissemination of Salmonella enterica subsp. enterica serovar Typhimurium.
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Leigh Knodler @leighknodler.bsky.social · 03/06/2025
Just a few spots remaining for the GRC Salmonella Biology and Pathogenesis meeting to be held in August. The final program is now online. www.grc.org/salmonella-b... Apply now to hear about the latest scientific discoveries about Salmonella, meet up with old friends, make new friends......
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Rob Kingsley @drrobkingsley.bsky.social · 14/05/2025
Interested in #Salmonella #genetics and / or #phage ? - check out our newly published manuscript that implicates the reversible deletion of the wzy gene in S. Typhimurium (and likely other important Salmonella serovars) in evasion of phage predation journals.plos.org/plosgenetics...
journals.plos.org
Reversible excision of the wzy locus in Salmonella Typhimurium may aid recovery following phage predation
Author summary Salmonella Typhimurium is a major pathogen of livestock that adversely affects productivity and animal welfare and poses a risk of foodborne disease in the human population. Antibiotics...
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Julie Pfeiffer @jkpfeiff.bsky.social · 28/04/2025
Terry Dermody and I wrote an op-ed about chronic diseases ("Make America Healthy Again"), the role of viral infections, and how virologists can help. www.post-gazette.com/opinion/gues...
post-gazette.com
Terrence S. Dermody and Julie K. Pfeiffer: To tackle chronic disease, turn to the virologists
Despite the United States being a global leader in many areas, Americans are not healthy. Life expectancy is lower than in other industrialized nations,...
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Andreas Bäumler @abaumler.bsky.social · 04/04/2025
🚨 Big news! Infection and Immunity is now open access! 🌍🔬 That means wider visibility & impact for your research. Worried about fees? 💸 Check out how IAI stacks up against other journals—you might be surprised. #OpenAccess #SciComm #Microbiology
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Antimicrobial resistance #AMR @antimicrobial.bsky.social · 06/02/2025
A University of Basel study shows that antibiotic failure is due to nutrient-starved Salmonella, not persister bacteria, as traditional methods underestimate surviving bacteria. Researchers suggest focusing on nutrient-related resilience to improve treatments. #AMR www.nature.com/articles/s41...
nature.com
Limited impact of Salmonella stress and persisters on antibiotic clearance - Nature
Experiments in infected mice and tissue-mimicking chemostats show that resilience of Salmonella against antimicrobial compounds is largely a result of starvation-induced general resilience rather than...
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Roli Roberts @roliroberts.bsky.social · 13/01/2025
Did 6-carbon sugars arrive late to the picnic? This one's fun: Steffen Lindner & Markus Ralser make a case for the primacy of pentose (5-carbon) metabolism in early evolution >4 billion years ago @plosbiology.org journals.plos.org/plosbiology/...
Pentose utilization pathways include all life-essential metabolic precursors as intermediates. The diagram shows essential biomass precursors as intermediates of canonical central metabolism routes (right), displayed in black dots (corresponding to the number of carbon atoms) and highlighted by blue frames. On the left are pentose interconversions (xylulose-5P, ribulose-5P, ribulose-1,3bisP, xylose) connected to biomass precursor molecules (middle) via colour-coded pathway arrows (Weinberg, Dahms, pentose phosphate, phosphoketolase, xylulose monophosphate, ribulose monophosphate, GND-Entner-Doudoroff, Rubisco pathways).
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Roli Roberts @roliroberts.bsky.social · 06/01/2025
Well, it's that time of year again. My best value-for-money annual donation; £1 per week (plus top-up) to help @wikimedia.bsky.social ensure that ~7 billion people have access to high-quality information in an info-depauperate age.
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PLOS Biology @plosbiology.org · 16/12/2024
PLOS Biology is a leading life science journal championing high-impact research across all disciplines—from molecules to ecosystems. We offer innovative formats and collaborative editorial support to ensure your work achieves its full scientific impact!
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Bjo:rn Schro:der @mucubacter.bsky.social · 09/12/2024
We are looking for 2 #postdoctoral fellows on #gutmicrobiota, #diet and the #gut mucosal barrier in #health and #disease! Details & Application: umustipendie.varbi.com/en/what:job/... Please share!! #postdoc #postdocjob #academicjobs #MicroSky #GISky #Microbiome #MicroSky #AcademicSky #PhdSky
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Nonia Pariente @npariente.bsky.social · 03/12/2024
Exciting! @plosbiology.bsky.social is preparing to disembark here where the sky is blue! Please give us a follow so you’ll get all of our lovely science directly to your timeline 😎😎
Bluesky profile page for PLOS Biology
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Roli Roberts @roliroberts.bsky.social · 03/12/2024
Our lovely journal, PLOS Biology, is shuffling impatiently on its perch, preparing to take flight into the Blue! Get ready to welcome us officially by following @plosbiology.bsky.social now!
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FEMS @femsmicro.org · 02/12/2024
We've already hit 100 followers! Thanks to everyone who has followed us so far. Spread the word :)
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Judith Behnsen @judith-behnsen.bsky.social · 25/11/2024
Excited to share that we are hiring a Bridge to Faculty Postdoc in Microbiology and Immunology at the University of Illinois Chicago. Please reach out if you have any questions about the program. And please share broadly. uic.csod.com/ux/ats/caree...
uic.csod.com
Bridge to Faculty Postdoctoral Research Associate in Microbiology and Immunology
Bridge to Faculty Postdoctoral Research Associate in Microbiology and ImmunologyThe Department of Microbiology and Immunology (MI) at the University o...
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Reposted by Sebastian Winter
Jay Hinton @jayhinton.bsky.social · 23/11/2024
Wild-type Salmonella Typhimurium uses PgtE protease to evade C3-mediated serum killing: Suggests that after escape from a macrophage, PgtE promotes systemic spread of the pathogen… Elegant work from @manuelar.bsky.social’s team at UCSD… www.biorxiv.org/content/10.1...
biorxiv.org
PgtE protease enables virulent Salmonella to evade C3-mediated serum and neutrophil killing
Non-typhoidal Salmonella serovars, such as Salmonella enterica serovar Typhimurium (STm), are a leading cause of inflammatory diarrhea in otherwise healthy individuals. Among children, the elderly, an...
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Andreas Bäumler @abaumler.bsky.social · 19/11/2024
The Department of Medical Microbiology and Immunology at the University of California Davis, School of Medicine, invites applications for a full-time faculty position in Microbiome Sciences. Apply by December 11th at: recruit.ucdavis.edu/JPF06847
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Jonathan Eisen @phylogenomics.bsky.social · 17/11/2024
Organic carrot recall www.usatoday.com/story/money/...
usatoday.com
Carrot recall announced in connection to E. coli outbreak: See list of affected products
More than a dozen brands are recalling bags of baby and whole organic carrots that were sold in 19 states for risk of E. coli contamination.
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Rob Kingsley @drrobkingsley.bsky.social · 15/11/2024
I am co-chairing the 'Evolutionary and comparative genomics' session at i3s Salmonella conference in St Malo in 2025 - will be great to see you there! i3scongress.sciencesconf.org/resource/pag... Submission deadline for abstracts : 30th November
i3scongress.sciencesconf.org
International Symposium on Salmonella and Salmonellosis - Sciencesconf.org
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Lauren Palmer @laurenpalmer.bsky.social · 15/11/2024
SO EXCITED to share our recent work on dietary zinc deficiency worsening Acinetobacter baumannii pneumonia, out today with @natureportfolio.bsky.social!! Surprisingly, this is due at least in part to the allergic-type cytokine IL-13. SharedIt link: rdcu.be/d0h4h Eat your zinc rich foods! 🦪🫘🧀🥩🥜
rdcu.be
Dietary zinc deficiency promotes Acinetobacter baumannii lung infection via IL-13 in mice
Nature Microbiology - Increased IL-13 drives increased bacterial dissemination and mortality following Acinetobacter baumannii lung infection of zinc-deficient mice and can be countered by...
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Jonathan Eisen @phylogenomics.bsky.social · 14/11/2024
Post doc position of possible interest at UC Davis: ohi.vetmed.ucdavis.edu/careers On "ecological and environmental drivers of zoonotic virus emergence, transmission and circulation and the development of innovative technology and approaches for transdisciplinary pandemic research."
ohi.vetmed.ucdavis.edu
Careers
Postdoctoral ResearcherSalary Range: $67,000-$79,000 USD per yearLocation: Onsite, UC DavisApplication Deadline: November 29, 2024
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Thomas P200 Burke @findmeinthelab.bsky.social · 13/11/2024
Our department at UC Irvine is recruiting for a tenure-track position in RNA biology! Assistant or Associate level, any area of RNA biology including in microbiology are encouraged to apply. Come join our vibrant research community in SoCal! recruit.ap.uci.edu/JPF09320
recruit.ap.uci.edu
Professor of RNA Biology and Molecular Genetics (tenure track/tenure)
University of California, Irvine is hiring. Apply now!
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Andreas Bäumler @abaumler.bsky.social · 12/11/2024
Your hitchhiker's guide to microbiome studies: journals.asm.org/doi/epub/10....
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Joe Zackular @joeyzacks.bsky.social · 04/10/2024
Delighted to share our work developing an mRNA vaccine for C. difficile. This study with Drew Weissman’s lab was co-led by two truly amazing scientists: Alexa Semon from the Zackular lab and Mohamad-Gabriel Alameh from CHOP (formerly Weissman lab)! www.science.org/doi/10.1126/...
science.org
A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection
Clostridioides difficile infection (CDI) is an urgent public health threat with limited preventative options. In this work, we developed a messenger RNA (mRNA)–lipid nanoparticle (LNP) vaccine targeti...
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Jonathan Eisen @phylogenomics.bsky.social · 17/09/2024
Assistant Professor of Teaching in the Dept. of Evolution and Ecology at UC Davis Open position in the Department of Evolution and Ecology at UC Davis (my home department). See recruit.ucdavis.edu/JPF06690
recruit.ucdavis.edu
Professor of Teaching (PoT)
University of California, Davis is hiring. Apply now!
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Andreas Bäumler @abaumler.bsky.social · 13/08/2024
Do you know an exceptional early-career investigator in host-microbe interactions? Don't miss this chance to nominate a rising star for our Infection and Immunity 2025 New Voices in Microbiology Collection by the August 30 deadline. Nominate now: deal.town/asm.org/reco...
deal.town
Recommend a Rising Star in the Field of Host-Microbe Interactions - asm.org
Please Note: Due to the high number of responses we receive to this annual call, the IAI editors have not been able to work with all the extraordinary candidates nominated in the past. If your candidate is still eligible, you are welcome to resubmit their nomination.
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