iiinova — where your digital self keeps evolving

Sean @seanlzheng.bsky.social · 21/08/2025

Great opportunity for someone to join our dynamic group @cvgenomics.bsky.social as a research assistant, where we are using genomics and transcriptomics to better understand heart disease. Closing date 27th August for applications! @mrc-lms.bsky.social @jamesware.bsky.social t.co/u68MZ6DDFD

t.co

https://lms.mrc.ac.uk/work/vacancies/research-assistant-2/

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The Polygenic Score Catalog @pgscatalog.bsky.social · 26/02/2025

Now available in the PGS Catalog 🔗: www.pgscatalog.org/publication/...! Thanks to authors like Sean for submitting the data directly, find out how to submit your data at pgscatalog.org/submit

pgscatalog.org

PGS Catalog - Zheng SL, Nat Genet (2025) (Publication)

The Polygenic Score (PGS) Catalog is an open database of published PGS and the relevant metadata needed to apply and evaluate them correctly.

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NHLI @imperialnhli.bsky.social · 18/02/2025

Doctors could soon begin offering patients and families personalised advice on their risk of developing hypertrophic cardiomyopathy, thanks to a new study on genomic risk scores that estimates risk based on a person's DNA 🧬🫀 www.imperial.ac.uk/news/261253/...

imperial.ac.uk

New genetic tests could predict future risk for deadly heart conditions | Imperial News | Imperial College London

Doctors could soon begin offering patients and families personalised advice on their risk of developing a potentially deadly heart muscle condition.

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Sean @seanlzheng.bsky.social · 18/02/2025

🧵 Polygenic scores in hypertrophic cardiomyopathy 📎 Paper: www.nature.com/articles/s41... in @naturegenet.bsky.social We created PGS using sumstats from our linked GWAS study www.nature.com/articles/s41..., evaluating it across a range of clinical settings in several cohorts. 1/n

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Sean @seanlzheng.bsky.social · 18/02/2025

🚨Our double header on genetics of hypertrophic #cardiomyopathy out today in @naturegenet.bsky.social 🧬 📍GWAS www.nature.com/articles/s41... 📍polygenic scores www.nature.com/articles/s41... A consortia effort by @jamesware.bsky.social Hugh Watkins @conniebezzina.bsky.social Rafik Tadros & Anuj Goel

nature.com

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Nature Portfolio @natureportfolio.nature.com · 27/11/2024

Genome-wide association analyses in Nature Genetics provide insights into the molecular etiology of dilated cardiomyopathy, which may inform the design of genetic testing strategies and may facilitate the development of targeted therapeutics. go.nature.com/4fIkNmh 🧪

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Sean @seanlzheng.bsky.social · 21/11/2024

🧬 Our dilated #cardiomyopathy GWAS out today! 📍https://www.nature.com/articles/s41588-024-01952-y All made possible with friends and collaborators from HERMES Consortium @alberthenry.bsky.social @tomlumbers.bsky.social @jamesware.bsky.social @mrc-lms.bsky.social @imperialnhli.bsky.social #BHF 🧵 👇

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