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Reposted by Sam Barnett Dubensky

bioRxivpreprint @biorxivpreprint.bsky.social · 05/08/2026

Tfh dysfunction underlies poor responses to HBV vaccination www.biorxiv.org/content/10.64898/20…

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Reposted by Sam Barnett Dubensky

bioRxiv Immunology @biorxiv-immuno.bsky.social · 05/08/2026

Tfh dysfunction underlies poor responses to HBV vaccination www.biorxiv.org/content/10.64898/20…

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Sam Barnett Dubensky @sbarnettdubensky.bsky.social · 22/07/2026

Looking forward to my thesis defense this Friday! (if you would like to join virtually please message me for the Zoom link)

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Reposted by Sam Barnett Dubensky

Keystone Symposia @keystonesymposia.bsky.social · 17/03/2026

🔥 19 scientists. 🌍 One global stage. Celebrating 19 @niaidnews.bsky.social awardees at our B Cells & Plasma Cells / B & T Cell Collaboration meeting! The future of immunology is here 👏 #KSBCells26 #KSBTCells26 @kimljacobson.bsky.social @deeptabhattacha.bsky.social @zivshulman.bsky.social

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Reposted by Sam Barnett Dubensky

Waggoner Lab @labwaggoner.bsky.social · 16/12/2025

Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans @biorxivpreprint.bsky.social www.biorxiv.org/content/10.6... @lauravella.bsky.social @derek-oldridge.bsky.social @pennmedicine.bsky.social

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Reposted by Sam Barnett Dubensky

Amy E. Baxter, PhD @amylizbaxter.bsky.social · 16/12/2025

Really excited to share this work from the @laura-a-vella.bsky.social and @derek-oldridge.bsky.social labs, led by an amazing MD/PhD student! Sam asked if Tfh spatially localised within germinal centers have distinct gene expression programs & identified GNG4 as a key feature of GC-positioned Tfh.

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Reposted by Sam Barnett Dubensky

Michela Locci @michelalocci.bsky.social · 16/12/2025

I am excited to share that our work, in which we have dissected the signals driven by the nucleoside-modified mRNA and LNP components of mRNA vaccines that regulate germinal center (GC) responses, is now published in Cell! www.cell.com/cell/fulltex...

cell.com

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

This study dissects the individual contributions of the different components of mRNA vaccines to immune responses. Nucleoside-modified mRNA promotes the production of type I interferons that act on de...

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Reposted by Sam Barnett Dubensky

Waggoner Lab @labwaggoner.bsky.social · 16/12/2025

@biorxivpreprint.bsky.social Dysregulated localization of Tfh and B cells in lymph nodes of Idiopathic multicentric Castleman disease patients www.biorxiv.org/content/10.6... @davidfajgenbaum.bsky.social

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Reposted by Sam Barnett Dubensky

Sam Barnett Dubensky @sbarnettdubensky.bsky.social · 15/12/2025

T follicular helper cells adopt alter egos and localize to diverse niches - what gene expression programs distinguish Tfh in the germinal center? After dissociating tissue samples into single-cell suspension, can we infer which Tfh were positioned in GCs? Check out our new preprint! bit.ly/3XVsrCI

bit.ly

Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans

CD4 T follicular helper (Tfh) cells coordinate humoral immune responses within germinal centers (GC) of lymphoid tissue. Despite their critical roles in vaccination and autoimmunity, the gene expressi...

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Reposted by Sam Barnett Dubensky

derek-oldridge.bsky.social @derek-oldridge.bsky.social · 15/12/2025

Very proud to share Sam’s work, jointly supervised between @laura-a-vella.bsky.social and my lab. His work exemplifies how to leverage the power of single-cell and spatialomics to uncover new insights into human GC Tfh biology and why studying human immunology matters: bsky.app/profile/sbar...

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Reposted by Sam Barnett Dubensky

Laura Vella @laura-a-vella.bsky.social · 15/12/2025

Incredibly happy to share Sam’s work between my lab and that of @derek-oldridge.bsky.social. What cellular programs are engaged by GC-positioned human Tfh? The answers held a few surprises.

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Reposted by Sam Barnett Dubensky

bioRxivpreprint @biorxivpreprint.bsky.social · 15/12/2025

Dysregulated lymphocyte localization in idiopathic multicentric Castleman disease www.biorxiv.org/content/10.64898/20…

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Reposted by Sam Barnett Dubensky

bioRxiv Immunology @biorxiv-immuno.bsky.social · 15/12/2025

Dysregulated lymphocyte localization in idiopathic multicentric Castleman disease www.biorxiv.org/content/10.64898/20…

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Sam Barnett Dubensky @sbarnettdubensky.bsky.social · 15/12/2025

bit.ly

Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans

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Reposted by Sam Barnett Dubensky

bioRxivpreprint @biorxivpreprint.bsky.social · 13/12/2025

Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans www.biorxiv.org/content/10.64898/20…

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Reposted by Sam Barnett Dubensky

bioRxiv Immunology @biorxiv-immuno.bsky.social · 13/12/2025

Multimodal analysis defines GNG4 as a distinguishing feature of germinal center-positioned CD4 T follicular helper cells in humans www.biorxiv.org/content/10.64898/20…

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