iiinova — where your digital self keeps evolving

Sattler Lab @sattler-lab.bsky.social · 10/08/2026

Looking back on a successful week filled with exciting NMR lectures, practicals and lots of scientific exchange at the EMBO Practical Course on Structural dynamics, interactions and function of biological macromolecules by #NMR 🧲🧬

051

Sattler Lab @sattler-lab.bsky.social · 30/07/2026

Exciting discussions and interactions between participants and instructors at the @embo.org Practical Course on Structural dynamics, interactions and function of biological macromolecules by #NMR 🧲🧬

092

Reposted by Sattler Lab

Florent Delhommel @florentdelh.bsky.social · 07/01/2026

Our latest work is now out in @cp-molcell.bsky.social ! We have looked at Sgt1, an essential Hsp90 co-chaperone in yeast. We determined its interaction with Hs90 and showed that it stabilises the chaperone-client complex and prevents its dissociation by Aha1. www.cell.com/molecular-ce...

Schematic showing the function of Sgt1 in yeast.

242

Sattler Lab @sattler-lab.bsky.social · 23/12/2025

Wishing everyone happy holidays with a little glimpse at our festive Christmas party 🎄🎁

031

Sattler Lab @sattler-lab.bsky.social · 05/12/2025

Congrats to our lab member Philipp, who defended his PhD this week! 🎓🎉

062

Reposted by Sattler Lab

Florent Delhommel @florentdelh.bsky.social · 17/11/2025

Our latest work is out! We combined #NMR with #Crystallography, #MD, and #ProteinMPNN to analyze the conformational dynamics of a de novo enzyme and redesigned it! Great collaboration between @cathleenzeymer.bsky.social and the @sattler-lab.bsky.social. www.cell.com/structure/fu...

graphical abstract showing the combination of techniques used to analyze the dynamics of a de novo enzyme.

096

Sattler Lab @sattler-lab.bsky.social · 11/11/2025

Looking back on an inspiring and stimulating two days at the Ultra-Highfield NMR and 4D Structural Biology Symposium. Huge thanks to all speakers, participants, and organizers for making this such an insightful and engaging event! 🧲🧬

094

Reposted by Sattler Lab

Helmholtz Munich @helmholtzmunich.bsky.social · 10/11/2025

Biomolecular Breathing and the 4D View of Life How do biomolecules breathe? This question was at the heart of the international #BNMRZ symposium, hosted by the Bavarian NMR Center – a joint infrastructure of #HelmholtzMunich and the @tum.de. 👉 Read more: t1p.de/dpfr7 #StructuralBiology #NMR #AI

Biomolecular Breathing and the 4D View of Life: Insights from the BNMRZ Symposium

062

Reposted by Sattler Lab

Bussi Lab @bussilab.org · 06/11/2025

Our work presented at the Ultra-Highfield NMR and 4D Structural Biology workshop www.bnmrz.org/4dstructbiol organized by @sattler-lab.bsky.social! @bussigio.bsky.social will show our works on #RNA dynamics integrating #MD, #SAXS, and #NMR and validating a #CASP16 target using #cryoEM data

bnmrz.org

BNMRZ - BNMRZ Symposium: Horizons for Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapeutics

073

Reposted by Sattler Lab

Helmholtz Munich @helmholtzmunich.bsky.social · 06/11/2025

#BNMRZ Symposium 2025 Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies 💻 Online attendance is still possible: t1p.de/zdr8j 👉 Further information: t1p.de/rjuz4 @tum.de #StructuralBiology #CryoEM #AI #TherapeuticInnovations

2126

Sattler Lab @sattler-lab.bsky.social · 13/10/2025

A member of our group, Luca Sperotto, successfully defended his PhD last week. Congratulations Dr. Luca! 🎓

0201

Reposted by Sattler Lab

UNLEASH @unleash-as.bsky.social · 23/09/2025

Morning sky-friends! We are delighted to share some ‘hot off the xray’ images from our talented scientists, Dr André Mourão & Ting Deng. They produced this beautiful diffraction of a compound bound to one of our protein targets whilst working with @esrf.fr

$on the left a picture of a crystal and on the right the xray diffraction of that crystal generated using a synchotron.$

0104

Reposted by Sattler Lab

Magnetic Resonance News @nmr900.bsky.social · 04/08/2025

BNMRZ Symposium Ultra-Highfield NMR and 4D Structural Biology – From Mechanisms to Therapies, November 6–7, 2025, TUM Institute for Advanced Study, Garching @ias-tum.bsky.social registration opens soon www.bnmrz.org/4dstructbiol #BNMRZ #NMRchat #NMR 🧲

0104

Reposted by Sattler Lab

Helmholtz Munich @helmholtzmunich.bsky.social · 13/08/2025

#HelmholtzMunich’s BNMRZ has joined Germany’s Instruct-ERIC Centre 🔬 Instruct-ERIC provides open access to advanced structural biology technologies. #BNMRZ advances innovation in #NMR methods, drug discovery, and imaging - boosting the German Centre’s capabilities. 👉 Read more: t1p.de/pjtyv

Helmholtz Munich Joins Germany’s Instruct-ERIC Centre for Structural Biology

1116

Sattler Lab @sattler-lab.bsky.social · 10/07/2025

One of our group members @clarahipp.bsky.social had the great opportunity to attend the Nobel Laureate Meeting last week in sunny Lindau ☀️ #lino25

092

Reposted by Sattler Lab

Florent Delhommel @florentdelh.bsky.social · 30/04/2025

New preprint is out! We've looked at the interactions of Sgt1 with Hsp90 in yeast and found some surprising results! We've also shown that in the presence of clients, Sgt1 prevents aha1 binding on Hsp90 and thus increases the substrate's dwell time. #NMR #chaperone www.biorxiv.org/content/10.1...

Schematic of Hsp90's conformational cycle and the effect of Sgt1 that stabilizes the client's complex and prevents Aha1 binding.

163