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Sandy Desrat

@sandydesrat.bsky.social
231 followers 508 following 11 posts

Organic & Medicinal Chemist Working on Natural Products @icsnlab.bsky.social @cnrs.fr @univparissaclay.bsky.social. Fascinated by Nature. ⛰️🌊🌳

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Sandy Desrat @sandydesrat.bsky.social · 30/04/2025
Very happy to welcome in our team @icsnlab.bsky.social @cnrs.fr Tiphaine Alves Cunha from @universitereims.bsky.social for her M1 internship. She is working on the identification of plant metabolites with activities on antibiotic resistance enzymes.
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Sandy Desrat @sandydesrat.bsky.social · 30/04/2025
Very happy to welcome Kossi Kpoezou in our team @icsnlab.bsky.social @cnrs.fr for 6 months thanks to a grant from France ambassy in Togo. Kossi is a 2nd PhD student from Lomé University in Togo working on antidiabetic plants.
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ICSN lab @icsnlab.bsky.social · 08/04/2025
Very happy to welcome today @icsnlab.bsky.social @cnrs.fr Dr Thomas Boddaert from ICMMO @univparissaclay.bsky.social for a conference on "Light driven domino reactions".
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YMCF de la SCT @ymcf-sct.bsky.social · 08/04/2025
Our new episode S2E9 of My Publication at a Glance is online! Gwenaëlle JÉZÉQUEL presents her work done @icsnlab.bsky.social @cnrs.fr in collaboration with IPMC & PIMIT. 👉 youtu.be/CYfKUFHT8PQ?...
youtu.be
EN - My Publication at a Glance - Gwenaelle Jezequel - S2E9
YouTube video by Young MedChem Forum – SCT
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YMCF de la SCT @ymcf-sct.bsky.social · 27/03/2025
Si vous manquez notre dernière session AskMeAnything #AMA avec Mélaine Kuenemannsur les métiers de la chémoinformat ique, retrouvez la video sur notre chaine Youtube youtu.be/hXhX1InSRV8?....
youtu.be
AskMeAnything avec Mélaine Kuenemann sur les métiers de la chémoinformatique dans l'industrie pharma
YouTube video by Young MedChem Forum – SCT
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Sandy Desrat @sandydesrat.bsky.social · 27/03/2025
Congratulations Isabel for this prize!
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ICSN lab @icsnlab.bsky.social · 27/03/2025
Emma Naulin, Isabel Ramon Martinez & Clémentine Mayet were awarded for the best bibliographical seminars @icsnlab.bsky.social @cnrs.bsky.social @univparissaclay.bsky.social. Congratulations to all of you!
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ICSN lab @icsnlab.bsky.social · 27/03/2025
We have the chance to welcome Evolene Deslignière as permanent researcher @icsnlab.bsky.social @cnrs.fr. She presents us today her work on "New approaches in mass spectometry for caracterisation of large proteic complexes".
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CNRS @cnrs.fr · 26/03/2025
#VaSavoir 🌊 Depuis 150 ans, à la station biologique de Roscoff on se mouille pour étudier l’océan et le protéger. Certaines méthodes perdurent, d’autres révolutionnent la compréhension du vivant et des écosystèmes. Embarquez avec notre reporter ! 🐠 👉 youtu.be/ezzrml6RBUM
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YMCF de la SCT @ymcf-sct.bsky.social · 26/03/2025
Notre dernière session #AMA @ymcf-sct.bsky.social consacrée au métier de chemo-informaticien/CADD Scientist a été un grand succès. Un grand merci à Mélaine Kueneman, senior scientist chez Hoffmann-La Roche à Bâle, Suisse, pour son intervention.
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Sandy Desrat @sandydesrat.bsky.social · 20/03/2025
A stroke of pencil in the sky this morning!
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Sandy Desrat @sandydesrat.bsky.social · 20/03/2025
A stroke of pencil in the sky this morning!
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YMCF de la SCT @ymcf-sct.bsky.social · 13/03/2025
New episode of "My Publication at a Glance" with Emanuela Berrino, Post-Doc @cea-paris-saclay.bsky.social. She presents her work on "Superacid-Synthesized Fluorinated Diamines Act as Selective hCA IV Inhibitors", published in J. Med. chem. @acsmedi.bsky.social. 👉 www.youtube.com/watch?v=Ii6g...
youtube.com
EN - My Publication at a Glance - Emanuela Berrino - S2E7
YouTube video by Young MedChem Forum – SCT
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Sandy Desrat @sandydesrat.bsky.social · 06/03/2025
Check out our last article published in #ChemMedChem @chemistryeurope.bsky.social about the synthesis of simplified analogs of antiviral macarangin B. Great work done by G. Jézéquel & J. Fargier @icsnlab.bsky.social @cnrs.fr @univparissaclay.bsky.social with #IPMC & #PIMIT. 👉 doi.org/10.1002/cmdc...
doi.org
Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability
Simplified analogues of macarangin B, a natural compound with potent OSBP-targeted antiviral activity against Zika virus were elaborated with the aim of enhancing metabolic stability. The most promis...
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EFMC @euromedchem.bsky.social · 12/03/2025
🌟 Attend the upcoming webinar on Automated High-throughput Chemistry Workflows in Drug Discovery at J&J, hosted by SEQT. Explore advancements in High-Throughput Experimentation (HTE), Lab Automation, flow chemistry, and AI/ML in chemical synthesis. 📆 March 25 at 3pm 🔗 buff.ly/g1EAbfx
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Sandy Desrat @sandydesrat.bsky.social · 12/03/2025
Very nice graffiti painting by #Rast dedicated to Einstein & Marie Curie in Palaiseau!
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Sandy Desrat @sandydesrat.bsky.social · 06/03/2025
Check out our last article published in #ChemMedChem @chemistryeurope.bsky.social about the synthesis of simplified analogs of antiviral macarangin B. Great work done by G. Jézéquel & J. Fargier @icsnlab.bsky.social @cnrs.fr @univparissaclay.bsky.social with #IPMC & #PIMIT. 👉 doi.org/10.1002/cmdc...
doi.org
Analogues of Natural Macarangin B Display Potent Antiviral Activity and Better Metabolic Stability
Simplified analogues of macarangin B, a natural compound with potent OSBP-targeted antiviral activity against Zika virus were elaborated with the aim of enhancing metabolic stability. The most promis...
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Université Paris-Saclay @univparissaclay.bsky.social · 05/03/2025
📢 Ne manquez pas la Journée "L’IA générative : un allié incontournable pour les chercheuses et chercheurs"   ➡️ Rejoignez-nous pour une journée dédiée aux usages de l’IA générative. 📅 24/03/2025 📍 ENS Paris-Saclay   Programme et inscription : tinyurl.com/3y72a94h
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ICSN lab @icsnlab.bsky.social · 05/03/2025
Alain SchuhlAlain Schuhl dans l'amphi de l'ICSN
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ICSN lab @icsnlab.bsky.social · 05/03/2025
Excellente journée d'échanges autour du @cnrs.fr de la chimie des substances naturelles et bien d'autres choses, lors de la visite de @alainschuhl.bsky.social, Jacques Maddaluno, Sandrine Sagan pour CNRS Chimie, accompagnés de Carole le Contel pour @cnrs-paris-saclay.bsky.social. Merci à tous 🙏
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Nicolas Blanchard @blanchard-lab.bsky.social · 28/02/2025
Great addition to a great team Sandy!
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John Prensner @johnprensner.bsky.social · 28/02/2025
How does living in space change the life around you? Salido et al report one of the neatest things I've read all month. Sampling bacteria in the international space station, they show how that environment is an extreme subset of bacterial diversity. 🧪 🧬 💻 #metagenomics www.cell.com/cell/fulltex...
cell.com
The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns
With long-term space travel and extraterrestrial habitation becoming feasible, understanding how space environmental exposures, microbial communities, and molecular profiles differ from Earth is cruci...
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Sandy Desrat @sandydesrat.bsky.social · 28/02/2025
Very happy to host Émilie Plantiveau in our team @icsnlab.bsky.social @cnrs-paris-saclay.bsky.social @univparissaclay.bsky.social. Coming from #ENSCMu Mulhouse, she starts to work on the synthesis of antileishmanial quinolones thanks to the support of @gsheads.bsky.social. Welcome Émilie !
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YMCF de la SCT @ymcf-sct.bsky.social · 28/02/2025
Notre prochaine session #AMA sera consacrée au métier de chemo-informaticien. Pour cela, vous aurez la chance de pouvoir interagir avec notre experte : Dr Mélaine Kueneman, senior scientist chez Hoffmann-La Roche à Bâle, Suisse. Intéressés, inscrivez vous dès maintenant : forms.gle/Ma7VxP2dbRuS...
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SCF ChemBio @scf-chembio.bsky.social · 17/02/2025
🎉 The winner of the SCF-ChemBio Young Investigator Award 2025 has been announced, and the honor goes to Arnaud Chevalier, ICSN (@achevalierchembio.bsky.social)! 🏆 Congratulations !👏 @scf-chembio.bsky.social @icsnlab.bsky.social‬
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YMCF de la SCT @ymcf-sct.bsky.social · 27/02/2025
Retrouvez l'intégralité de la dernière session AskMeAnything #AMA avec Rebecca Deprez & Kim Spielmann sur les métiers de la chimie médicinale après des études de pharmacie sur notre chaine YouTube @ymcf-sct.bsky.social. 👉 youtu.be/a2hEz60_eXM?...
youtu.be
AskMeAnything avec Rebecca Deprez & Kim Spielmann sur les métiers de la chimie médicinale
YouTube video by Young MedChem Forum – SCT
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EFMC Young Scientists Network @youngscinet.bsky.social · 14/02/2025
📢 Don't miss the 20th MedChemBioOnline on Emerging Strategies in Peptide Drug Discovery! This edition will showcases strategies by research leaders to identify peptide hits and develop new medicines. 📆 March 4, 2025 (16:30 to 18:30 CET) 🔗 buff.ly/44OXtgk
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Sandy Desrat @sandydesrat.bsky.social · 31/01/2025
Merci à Life Sciences UPSaclay @univparissaclay.bsky.social pour cette mise en lumière de nos travaux sur la Macarangine B réalisés @icsnlab.bsky.social & à l'IPMC, publiés dans J. Med. Chem. @acsmedi.bsky.social. 👉 sco.lt/8ysbkO
sco.lt
Une nouvelle molécule naturelle, la macarangine B permet de préciser la fonction biologique de la protéine OSBP | Life Sciences Université Paris-Saclay
Les composés naturels ciblant la protéine OSBP (OxySterol Binding Protein), connus sous le nom d'ORPphilines, suscitent un intérêt croissant en raison de leurs propriétés anticancéreuses prometteuses,...
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Véronique Michelet @vmichelet06.bsky.social · 25/02/2025
🥳Women Chemists in France in 2025: extremely honored to be part of this special issue and proud of my 👩 team for this project !! @kristinaplevova.bsky.social comptes-rendus.academie-sciences.fr/chimie/item/... Happy to be with @massongroup.bsky.social @bessettatiana.bsky.social 😊
comptes-rendus.academie-sciences.fr
Women Chemists in France in 2025
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YMCF de la SCT @ymcf-sct.bsky.social · 26/02/2025
Great success for our last #AMA session dedicated to the medchem jobs after pharma studies! A big thanks to our invited experts: Pr Rebecca Deprez-Poulain @univlille.bsky.social @pasteurlille.bsky.social & Dr Kim Spielmann from @evotec.bsky.social.
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Université Paris-Saclay @univparissaclay.bsky.social · 20/02/2025
📢 Save the date : Journée “l’IA générative : un outil du quotidien pour les chercheuses et chercheurs »   ➡️ Rejoignez-nous pour une journée dédiée aux usages de l’IA générative. 📅 24/03/2025 📍 ENS Paris-Saclay   Programme et inscription : tinyurl.com/39drzvcv
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YMCF de la SCT @ymcf-sct.bsky.social · 26/02/2025
We are now on @bsky.app ! We are group of young academic and industrial researchers, named Young MedChem Forum @ymcf-sct.bsky.social created by the French medicinal chemistry society (SCT) with the aim of supporting young medicinal chemists and students. www.sct-asso.fr/presentation...
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snorsikian.bsky.social @snorsikian.bsky.social · 14/02/2025
Happy to share our work in collaboration with Fanny Roussi & @sandydesrat.bsky.social @icsnlab.bsky.social @cnrs.fr on "Fast and effective preparation of highly cytotoxic hybrid molecules of schweinfurthin E and OSW-1" published in Organic & Biomolecular Chemistry pubs.rsc.org/en/content/a...
pubs.rsc.org
Fast and effective preparation of highly cytotoxic hybrid molecules of schweinfurthin E and OSW-1
Herein, we present the first synthesis of hybrid molecules combining the pharmacophores of two natural compounds, schweinfurthin E (SW-E) and the glycosidic moiety of OSW-1. These hybrids were designe...
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Waser Group @lcsolab.bsky.social · 13/02/2025
Next edition of #LCSOSynthesisProblem www.linkedin.com/feed/update/...
linkedin.com
LCSO Lab on LinkedIn: #lcsosynthesisproblem #lcsosynthesisproblem
#LCSOSynthesisProblem is back this week with Helena, who challenged us to the total synthesis of (±)-Jujuyane by Lee and co-workers! Want to challenge…
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Indira David @im74ve.bsky.social · 13/02/2025
Congrats to all the winners and participants of the scientific journey @gsheads.bsky.social amazing organization, presentations, projects, collaborations and interactive workshops! Well done👍👏👏👏 @univparissaclay.bsky.social @pharmaupsaclay.bsky.social #Alltheteam 💪🏼👏👏👏
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Futura @futurasciences.bsky.social · 12/02/2025
ICYMI: Des arbres « fossiles vivants » sont plantés dans des endroits secrets... Mais pourquoi ?
futura-sciences.com
Des arbres « fossiles vivants » sont plantés dans des endroits secrets... Mais pourquoi ?
Un #arbre préhistorique ressuscité contre toute attente ! Le #pindeWollemi, que l'on croyait disparu depuis des millions d'années, renaît de ses cendres. Découvrez l'incroyable odyssée de cette espèce rescapée du temps et les efforts titanesques déployés…
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Sandy Desrat @sandydesrat.bsky.social · 12/02/2025
Very honored to talk about the isolation and design of antiviral cyclopeptides during the scientific days of @gsheads.bsky.social @univparissaclay.bsky.social. A big thanks to all the contributors @icsnlab.bsky.social @cnrs.fr and at Univ La Réunion and to SATT Paris Saclay for financial support.
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Denis DAVID @denisjdavid.bsky.social · 11/02/2025
Lancement des 4eme journées scientifiques GS HeaDS en partenariat avec OI HEALTHI par Pr Delphine Joseph, Directrice GS et Marc Pallardy, Doyen UFR pharmacie @pharmaupsaclay.bsky.social @univparissaclay.bsky.social @delfjoseph.bsky.social @gsheads.bsky.social
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EFMC @euromedchem.bsky.social · 06/02/2025
📢 Announcing the 2025 EFMC-YSN Leadership Election! We are glad to introduce Sean McKenna, Laia Josa-Culleré, and Etienne Donckele as the new leaders of the Young Scientists Network. Congratulations! Reach out for future collaborations! @seanmckenna.bsky.social @laiajosacullere.bsky.social
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Astropierre @astropierre.com · 08/02/2025
En raison des dérives de X, dont l'algo semble rendre complètement inopérant le partage d'informations scientifiques & la confrontation sereine des idées, le Conseil Scientifique du @cnrs.bsky.social invite les instituts & laboratoires affiliés à évaluer la pertinence de leur présence sur X. 1/2
Communiqué du Conseil Scientifique du CNRS recommandant aux institutions et laboratoires de recherche affiliés à évaluer la pertinence de leur présence sur une plate-forme aussi toxique que X.
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Frank Glorius @gloriusfrank.bsky.social · 07/02/2025
Scholarly review written by @DirkTrauner and @GloriusGroup: Reaction development: a student's checklist📜☑️😀 Published in Chem. Soc. Rev. doi.org/10.1039/d4cs...
doi.org
Reaction development: a student's checklist
So you’ve discovered a reaction. But how do you turn this new discovery into a fully-fledged program that maximises the potential of your novel transformation? Herein, we provide a student's checklist...
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ideevl.bsky.social @ideevl.bsky.social · 07/02/2025
Venez à l'IDEEV ( 12 route 128, 91190 Gif-sur-Yvette) à l'occasion des Journées de l'Agriculture le 6 juin de 9h30 à 12h. Des scientifiques vous font découvrir les expériences dans les champs. Sur inscription: forms.gle/oz12iJLFRs3h...
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France Culture @franceculture.fr · 07/02/2025
Une plante peut guérir. La même peut tuer. Les Grecs avaient un mot pour ça. ➡️ l.franceculture.fr/pkA
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Larry Miller, PhD @larrymillerphd.bsky.social · 07/02/2025
🔬🧪🧬 Preparing for a Postdoc? Be proactive! Here are key tips to help find a great experience: ✔️ Define your WHY for a postdoc ✔️ Ask the right Qs about expectations & support ✔️ Balance research & career development ✔️ Use IDPs to align goals with mentors #Postdoc #PhD #CareerDevelopment #STEM
insidehighered.com
How to prepare proactively for a postdoc (opinion)
These are some actions a Ph.D. student can take to pave the way for a positive postdoc experience, Chris Smith writes.
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ICSN lab @icsnlab.bsky.social · 06/02/2025
Thank you @idylle-labs.bsky.social for showing us today @icsnlab.bsky.social @cnrs.bsky.social @univparissaclay.bsky.social your process of valorisation of research tools developed in our labs!
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Organic Chemistry Division from the SCF @scf-dco.bsky.social · 09/01/2025
🚨Save the date!!!🚨The next SCF Division de Chimie Organique (DCO) Spring Meeting will take place on March 26th at the Université Claude Bernard in Lyon 1. Stay tuned for more information!
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Graduate School Health and Drug Sciences @gsheads.bsky.social · 08/01/2025
[JOURNEES SCIENTIFIQUES] La Graduate School "Health and Drug Sciences" (GS HeaDS) et l'Objet Interdisciplinaire "Health and Therapeutic Innovation" (OI HEALTHI) vous invitent à participer à leurs Journées Scientifiques. Inscription : framaforms.org/inscription-...
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Sandy Desrat @sandydesrat.bsky.social · 05/02/2025
The story of meiogynin A isolated in 2009 in our team @icsnlab.bsky.social & its analogs is not finished! A big thanks to Hugo Fraga @i3suporto.bsky.social, Diego Gauto @icsnlab.bsky.social & all contributors for this work on the identification of new ClpC1-NTD binders! Check out 👉 rdcu.be/d8Ip5
rdcu.be
Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development
Scientific Reports - Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development
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Waser Group @lcsolab.bsky.social · 03/02/2025
Next #LCSOSynthesisProblem is ready www.linkedin.com/feed/update/...
linkedin.com
LCSO Lab on LinkedIn: #lcsosynthesisproblem #lcsosynthesisproblem
This week on the #LCSOSynthesisProblem, Christine challenged us with the total synthesis of (+)-Mannolide B by Jia and co-workers! Want to challenge yourself…
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Sandy Desrat @sandydesrat.bsky.social · 31/01/2025
Merci à Life Sciences UPSaclay @univparissaclay.bsky.social pour cette mise en lumière de nos travaux sur la Macarangine B réalisés @icsnlab.bsky.social & à l'IPMC, publiés dans J. Med. Chem. @acsmedi.bsky.social. 👉 sco.lt/8ysbkO
sco.lt
Une nouvelle molécule naturelle, la macarangine B permet de préciser la fonction biologique de la protéine OSBP | Life Sciences Université Paris-Saclay
Les composés naturels ciblant la protéine OSBP (OxySterol Binding Protein), connus sous le nom d'ORPphilines, suscitent un intérêt croissant en raison de leurs propriétés anticancéreuses prometteuses,...
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