Achieving stereochemical control in SN1-type nucleophilic substitution reactions is challenging due to the complexity of the successive carbocation intermediates. Now a strategy using neighbouring gro...

The suitability of synthetic protocols for a target molecule can be evaluated by analyzing reaction scopes of possible literature procedures. Whereas trial-and-error screening of reaction conditions i...

TRIBUNE. En écho au mouvement américain de protestation contre la politique de Donald Trump, un collectif de personnalités françaises appelle citoyens et scientifiques à rejoindre le mouvement « Stand...

Aliphatic C–H functionalization is a valuable tool in organic synthesis. Now a hypervalent iodine reagent has been shown to release a potent hydrogen atom abstractor for C–H activation under mild phot...

From code on a Titan to becoming the titan of crystal structure determination