Genetic reduction of the translational repressors FMRP or 4E-BP2 prevents amyloid-β oligomer–induced suppression of hippocampal protein synthesis and memory loss in mice. Targeting translational cont....

Background Racemic ketamine and its enantiomer, esketamine, have emerged as fast-acting antidepressant options for individuals with treatment-resistant depression (TRD). Yet, despite growing clinical ...

Call for CANGlia 2026 Symposia Proposals | Deadline: December 31st, 2025 The Canadian Association for Neuroscientists who study Glia (CANGlia) is now accepting Proposals for the 2026 CANGlia Meeting in Montreal (May 15-16th, 2026), with a deadline of Wednesday, December 31st, 2025. Please see below for more details and do not hesitate to reach out …

Neuropsychopharmacology - Psilocybin therapy for mood dysfunction in Parkinson’s disease: an open-label pilot trial

Boosting the recycling process known as autophagy — impaired in the brain during prolonged stress — has the potential to restore normal neuronal activity and treat depression.

Microglia have key roles in CNS development and neurodegeneration. Here, the authors provide an overview of microglia heterogeneity, cell-state annotation and model systems.