Sign in

Giulio Ruffini

@ruffini.bsky.social
408 followers 238 following 105 posts

Physicist working on computational neuroscience, brain stimulation and foundational aspects of (meta)physics, swimming and music during spare CPU cycles. Neuroelectrics.com, Starlab.es, BCOM.one

PostsRepliesMedia
Reposted by Giulio Ruffini
Ricard Solé @ricardsole.bsky.social · 11/09/2026
La IA como un virus cognitivo: comentario en @lavanguardia.com acerca de nuestra investigación reciente @ruffini.bsky.social @francesca-castaldo.bsky.social @sfelena.bsky.social @brigan.bsky.social www.lavanguardia.com/vida/2026091...
081
Reposted by Giulio Ruffini
Neuroelectrics @neuroelectrics.bsky.social · 10/09/2026
Can adapting brain circuitry help prevent suicide? On #WorldSuicidePreventionDay, every advancement in understanding and treating depression is a step forward in the fight against suicide. Learn more: youtube.com/watch?v=pqBc... #MentalHealth #Neuromodulation
youtube.com
Suicide Prevention by Adapting Brain Circuitry
YouTube video by Neuroelectrics
021
Giulio Ruffini @ruffini.bsky.social · 10/09/2026
Algorithmic emergence: the event where an observer/agent discovers a useful representation and reusable model that reveal regularity it could not use before. Compression may not exist—and even when it does, every reliable method that always halts has blind spots.
110
Reposted by Giulio Ruffini
Ricard Solé @ricardsole.bsky.social · 04/09/2026
Can AI spread like a virus and erode cognitive autonomy? Our new paper models how LLM adoption can cross tipping points, triggering runaway dependence and tech lock-in, suggesting routes to "cognitive immunization". arxiv.org/abs/2609.03344 @ruffini.bsky.social @francesca-castaldo.bsky.social
14716
Giulio Ruffini @ruffini.bsky.social · 13/07/2026
New preprint out! => The cortical column as a tuned receiver: a network mechanism for temporal-interference stimulation. We propose a mechanism for #TI leveraging oscillatory computation in the brain. How? Nonlinearity + resonant network amplification, like AM radio! 📻 doi.org/10.5281/zeno...
010
Giulio Ruffini @ruffini.bsky.social · 13/07/2026
What survives the Filter of Time? Will we? What do a proton, a flame, a chemotactic cell, and an LLM agent have in common? ⚛️🧬🐕🤖 (fast intro: giulioruffini.com/blog/) @bcom-foundation.bsky.social
211
Giulio Ruffini @ruffini.bsky.social · 06/07/2026
The things that stay. @bcom-foundation.bsky.social You cannot step into the same river twice—but the river remains. 🌊 From Aristotle to Alan Turing, how do we persist when our atoms are constantly replaced? #Philosophy #CognitiveScience #KT giulioruffini.github.io/assets/blogs...
141
Giulio Ruffini @ruffini.bsky.social · 28/03/2026
The transformer has no memory. Some thoughts on LLMs, memory, RAG, and how to use Claude. bcomone.atlassian.net/wiki/spaces/... @bcom_foundation @bcom-foundation.bsky.social @francesca-castaldo.bsky.social
141
Giulio Ruffini @ruffini.bsky.social · 16/03/2026
All algorithmic agents welcome here!
051
Giulio Ruffini @ruffini.bsky.social · 03/03/2026
Do you need to understand the world to survive in it? A classic 1970 cybernetics theorem says yes: "Every good regulator of a system must be a model of that system." But proving this mathematically for complex, unpredictable real-world scenarios has always been notoriously difficult. 1/5
120
Giulio Ruffini @ruffini.bsky.social · 16/02/2026
This is the paper where, after almost 20 years, I started taking my AIT obsessions a bit more seriously. I am happy I did... maybe you have some too... => Don't wast time! : ) academic.oup.com/nc/article/2... PS: the Supplementary Data part is more fun!
110
Giulio Ruffini @ruffini.bsky.social · 15/02/2026
An Introduction to Galois Theory (with connections to AIT): zenodo.org/records/1845... ...This note aims to demystify Galois Theory by connecting its foundational definitions to a broader principle of computational and compositional tractability.
150
Giulio Ruffini @ruffini.bsky.social · 15/02/2026
From The Sorcerer's Apprentice to Crystal Nights: Security Implications from Moltbot/Moltbook to Greg Egan's Crystal Nights! zenodo.org/records/1844...
000
Reposted by Giulio Ruffini
Ricard Solé @ricardsole.bsky.social · 14/02/2026
Could life have begun with simpler molecules than we once thought? A new paper in @science.org by @edogia.bsky.social shows that a tiny RNA catalyst can self-replicate itself, suggesting that life may have been easier to emerge than expected. Getting closer. www.biorxiv.org/content/10.1...
14718
Reposted by Giulio Ruffini
Ricard Solé @ricardsole.bsky.social · 12/02/2026
What if we had a Rosetta Stone for brain oscillations—one framework to translate between models and scales? In this paper lead by F Castaldo and @ruffini.bsky.social they build a simple, systematic ladder of neural mass models showing how diverse formalisms connect arxiv.org/pdf/2512.10982
1195
Giulio Ruffini @ruffini.bsky.social · 31/12/2025
My annotated slides for my talk in the wonderful thoughtforms.life/symposium-on... organized by @drmichaellevin are here: giulioruffini.github.io/assets/slide...
010
Giulio Ruffini @ruffini.bsky.social · 19/12/2025
Impressed: #notebooklm created a nice presentation of the Algorithmic Agent and Symmetry paper! github.com/giulioruffin...
github.com
210
Giulio Ruffini @ruffini.bsky.social · 15/12/2025
1/ 🧠 New in Computational Neuroscience: "Rosetta Stone of Neural Mass Models." An unifying framework connecting harmonic oscillator with Stuart-Landau, Wilson-Cowan, NMM1 & NMM2 (next generation). W. @Castaldo_Fr, R de Palma Aristides, P Clusella & J Garcia-Ojalvo - arxiv.org/abs/2512.109...
130
Giulio Ruffini @ruffini.bsky.social · 05/11/2025
New preprint 🪢: Neural Encoding through Hierarchical Amplitude Modulation (HAM). Slower rhythms multiplicatively modulate the amplitude of faster ones, so information can live in signals, their envelopes, and envelopes‑of‑envelopes. 1/5
121
Giulio Ruffini @ruffini.bsky.social · 15/10/2025
News🥁! Preprint on an AIT version of the Good Regulator Theorem. World (W) and Regulator (R) are Turing machines interacting via "interface" tapes. Regulation =: compression of W output (e.g., x = temperature series of a room). #Cybernetics #AlT #ActiveInference arxiv.org/abs/2510.10300 1/9
World and Regulator as coupled Turing machinesWorld and Regulator as coupled systems
220
Giulio Ruffini @ruffini.bsky.social · 11/07/2025
My slides from The Science of Consciousness (Barcelona 2025) Plenary talk this week! "From Kolmogorov Theory to Computational Modeling and Brain Stimulation". #consciousness #neuromodulation
131
Giulio Ruffini @ruffini.bsky.social · 11/07/2025
Here's our poster – "Algorithmic Structure and Lie Groups" – at ICMNS 2025 (Barcelona): www.dropbox.com/scl/fi/qbn55... It is a summary of our recent paper, Structured Dynamics in the Algorithmic Agent (www.mdpi.com/1099-4300/27...).
110
Reposted by Giulio Ruffini
Neuroelectrics @neuroelectrics.bsky.social · 19/06/2025
🔬🧠 Can optimized stimulation protocols offer better outcomes for major #depression? This randomized trial, featuring our @ruffini.bsky.social and Ricardo Salvador, & our friend Mohammad Ali Salehinejad, used our Starstim (www.neuroelectrics.com/products/res...) to deliver multichannel tDCS.
Efficacy of optimized multichannel vs conventional tDCS for major depression treatment: A randomized controlled trial. Starstim. Neuroelectrics
121
Reposted by Giulio Ruffini
Neuroelectrics @neuroelectrics.bsky.social · 29/04/2025
How can brain stimulation uncover patterns of cognitive decline in #AlzheimersDisease? 🔍 This study, featuring our CTO @ruffini.bsky.social used our Starstim (www.neuroelectrics.com/products/res...) to explore how 40 Hz tACS-EEG gamma activity relates to cognitive severity & inflammation.
Preliminary Evidence for Perturbation-Based tACS-EEG Biomarkers of Gamma Activity in Alzheimer's Disease. Starstim. Neuroelectrics
131
Giulio Ruffini @ruffini.bsky.social · 10/04/2025
🧵 Thread: 1. The Laminar Neural Mass Model (LaNMM) — A Unified Framework for Oscillatory Dynamics in Health and Disease (news!) The Laminar Neural Mass Model (LaNMM) links circuit-level mechanisms to M/EEG biomarkers across brain states — from healthy function to disease and altered consciousness.
120
Giulio Ruffini @ruffini.bsky.social · 13/02/2025
Blog! Post on our recent paper on symmetry, dynamics and neural networks (wet or dry) for the Entropy Special issue on “The Mathematics of Structured Experience: Exploring Dynamics, Topology, and Complexity in the Brain," still welcoming contributions! => www.neuroelectrics.com/blog/bridgin...
neuroelectrics.com
Bridging Dynamics, Symmetry, and Consciousness in Brain Modeling
Discover how brain dynamics and symmetry shape cognition, neural networks, and structured experience through mathematical modeling and information compression.
072
Giulio Ruffini @ruffini.bsky.social · 13/01/2025
I am happy to announce that an updated/improved version of "Structured dynamics in the algorithmic agent" has been released! www.biorxiv.org/content/10.1... We bridge perspectives from AIT (Kolmogorov C., compression), symmetry (group theory), and dynamics (conservation laws, reduced manifolds).
biorxiv.org
Structured dynamics in the algorithmic agent
In the Kolmogorov Theory of Consciousness, algorithmic agents utilize inferred compressive models to track coarse-grained data produced by simplified world models, capturing regularities that structur...
040
Giulio Ruffini @ruffini.bsky.social · 23/12/2024
LLMs aren’t just statistical 🦜s. Learning the probability of the next letter based on the prior 100 brute-force would involve ~28¹⁰⁰ possibilities. This is cosmically impossible: ~28¹⁰⁰ is more than the atoms in the universe! 🌌 Instead, LLMs learn patterns—compressing vast amounts of information...
arxiv.org
Information, complexity, brains and reality (Kolmogorov Manifesto)
I discuss several aspects of information theory and its relationship to physics and neuroscience. The unifying thread of this somewhat chaotic essay is the concept of Kolmogorov or algorithmic complex...
151
Giulio Ruffini @ruffini.bsky.social · 23/12/2024
🧵 Exciting research! Can serotonergic psychedelics help restore brain oscillatory dynamics disrupted in Alzheimer’s Disease (AD)? A personalized laminar whole-brain model sheds light. #Neurodegeneration #Psychedelics biorxiv.org/content/10.1... @neurotwin @Neuroelectrics
biorxiv.org
130
Reposted by Giulio Ruffini
David Chalmers @davidchalmers.bsky.social · 23/11/2024
roombas are my go to example to test theories of AI minds. they have beliefs (well, maps), desires (well, goals), plans (well, schedules), embodiment, and more. what else could you ask for?
3224
Reposted by Giulio Ruffini
Johannes Kleiner @johanneskleiner.bsky.social · 12/11/2024
Two starter packs for Consciousness Science! (A) go.bsky.app/CgkfpXZ (B) go.bsky.app/T8z9NP4
317829
Reposted by Giulio Ruffini
Earl K. Miller @earlkmiller.bsky.social · 23/11/2024
Huge influx of neuroscientists migrates to Bluesky www.thetransmitter.org/community/hu... #Neuroscience
thetransmitter.org
‘Huge influx’ of neuroscientists migrates to Bluesky
Daily neuroscience-related posts on the social-media platform this week have increased more than 400 percent, on average, compared with October.
742579
Giulio Ruffini @ruffini.bsky.social · 15/11/2024
Our KT-MDD paper is out! 🎉 “The Algorithmic Agent Perspective and Computational Neuropsychiatry: From Etiology to Advanced Therapy in Major Depressive Disorder” 📖 Published in the Special Entropy issue honoring Karl Friston’s 65th birthday. Read it here. mdpi.com/1099-4300/26... 1/n
mdpi.com
The Algorithmic Agent Perspective and Computational Neuropsychiatry: From Etiology to Advanced Therapy in Major Depressive Disorder
Major Depressive Disorder (MDD) is a complex, heterogeneous condition affecting millions worldwide. Computational neuropsychiatry offers potential breakthroughs through the mechanistic modeling of thi...
410
Reposted by Giulio Ruffini
Shawn Prest @shawnprest.bsky.social · 24/10/2024
A great paper on understanding Pure Awareness and MPE by Edmundo Lopez-Sola, @ruffini.bsky.social et al. osf.io/preprints/ps...
032
Giulio Ruffini @ruffini.bsky.social · 16/12/2023
New preprint for the KT framework released! After Neural Geometrodynamics (www.biorxiv.org/content/10.1...) comes Structured Dynamics in the Algorithmic Agent. sciencecast.org/casts/jq63ve...
030