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Rubin Dasgupta @rubindg.bsky.social · 16/08/2026

I am starting to frame ERC StG and I am conflicted about this question. How much data is considered preliminary data? Will showing protein dynamics and characterising it completely is good or showing that proteins can be produced efficiently? #Science #ERC

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Reposted by Rubin Dasgupta

paulschanda.bsky.social @paulschanda.bsky.social · 14/06/2026

📢 New publication. We answered an old question in structural biology: (how) does the crystal lattice impact proteins? In particular, how does the crystal restrict the protein's dynamics? We used local probes of dynamics: the rotation of aromatic rings. 🧵 www.nature.com/articles/s41...

nature.com

Aromatic ring flips reveal reshaping of protein dynamics in crystals and complexes - Nature Chemistry

The extent to which crystal packing constrains protein dynamics is hard to decipher. Now a combination of NMR, crystallography and molecular dynamics simulations show that intermolecular contacts can ...

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Reposted by Rubin Dasgupta

Christian Steinmetzger @stonebutcher.bsky.social · 08/09/2025

Check out our new method for targeted DNP-enhanced NMR of RNA using site-directed spin labeling, now live as a preprint on ChemRxiv: doi.org/10.26434/che... A fruitful collaboration with my colleague @rubindg.bsky.social and the group of Prof. Snorri Th. Sigurdsson from the University of Iceland.

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Rubin Dasgupta @rubindg.bsky.social · 27/05/2025

Looking forward to discuss #RNA #Science at the 30th @rnasociety.bsky.social meeting. I will be presenting our recent work on employing state-of-the-art #solid-state #NMR methods to study dynamics in microRNA-Argonaute complex in the Concurrent session 16 about miRNA and siRNA (T-149).

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Rubin Dasgupta @rubindg.bsky.social · 09/01/2025

For the last year I spent sometime learning #ONT #Nanopore sequencing and we decided to get this amazing P2 Solo. Can’t wait to start acquiring some in-house data. #RNAbiology #ChemicalProbing #RNA

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