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Radek Nowak

@rpnowak.bsky.social
406 followers 323 following 3 posts

Professor @UniBonn. Former @DanaFarber @harvardmed | Targeted Protein Degradation | Chemical and Structural Biology | @UniofOxford alumni. Tweets are my own.

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Reposted by Radek Nowak
Dan Nomura @dannomura.bsky.social · 09/01/2025
Congrats to ⁦‪Frontier Medicines‬⁩ on their covalent p53 Y220C activator FMC-220! www.globenewswire.com/news-release...
globenewswire.com
Frontier Medicines Announces FMC-220, the First Covalent p53 Y220C Activator Development Candidate, with Best-in-Class Potential
FMC-220 is a first-in-class covalent activator of p53Y220C designed to address potency and tolerability challenges of non-covalent approachesIn preclinical...
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Radek Nowak @rpnowak.bsky.social · 05/12/2024
Exciting science at the Advances in Therapeutic Symposium in Frankfurt! #goTPD #molecularGlues www.theranova.eu/en/veranstal...
theranova.eu
Program Advances in Therapeutic Approaches
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Reposted by Radek Nowak
Alessio Ciulli @alessiociulli.bsky.social · 03/12/2024
So privileged that CHI-Healthtech brought their flagship #DDC conference to Europe, in sunny ☀️ Barcelona! Enjoying tapas and sangria with Heide Düvel @chemb.bsky.social @rpnowak.bsky.social Gopal Sapkota, Ed Tate @nurkocaturk.bsky.social Hannah Peters, Rima Alawar. Thanks for the invitation Tanuja!
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Reposted by Radek Nowak
Shourya Roy Burman @ssroyburman.bsky.social · 27/11/2024
Through a series of cryo-EM structures, this study shows how an E2 and ubiquitin itself can play a "structural" role to specify ubiquitin linkage. 🧪 Lovely work by Katrina Warner, @moritzhunkeler.bsky.social @kheewoongbaek.bsky.social, @katherinedonovan.bsky.social and others in the Fischer Lab!
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Reposted by Radek Nowak
Cell Chemical Biology @cp-cellchembiol.bsky.social · 27/11/2024
Online! An engineered cereblon optimized for high throughput screening and molecular glue discovery by H. Bailey, J. Eisert, Fiona Sorrell @Fi_in_Frankfurt, Ivan Dikic @iDikic2 et al at @goetheuni @IBC2_GU @MPIBP @merckgroup dlvr.it/TGRD4Y
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Radek Nowak @rpnowak.bsky.social · 27/11/2024
Hi BlueSky! Now expanding reach here as well. Go go #ScienceTwitter or should it be #ScienceBlueSky?
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Radek Nowak @rpnowak.bsky.social · 27/11/2024
Was great to contribute to this story together with JanGerhartz Dominika Pienkowska Ina Dressel & Thomas Geiger from the lab. #CRBN #Interactome #GLUES authors.elsevier.com/sd/article/S... Animation credit PROXIDRUGs. Thanks for fantastic colaboration.
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