iiinova — where your digital self keeps evolving

Reposted by Roman Tsukanov

BIOspektrum @claudialudy.bsky.social · 05/10/2026

Ein internationales Forschungsteam unter Leitung der @uni-goettingen.de nutzt „selbstblinkende“ Farbstoffe für die Single-Molecule Localization Microscopy. 10.0.3.253/acs.nanolett... @romantsukanov.bsky.social Bild: © Roman Tsukanov, Nano Letters (2026); DOI: 10.1021/acs.nanolett.6c02799

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Sonja Schmid @scisonja.bsky.social · 30/09/2026

Glad to present #Nanophotonic DyeCycling – #BenjaminVermer’s magnum opus! 🎉 By breaking the longstanding photobleaching limitation in single-molecule #FRET, we achieve longterm observations of conformational #dynamics – gaining >1 order of magnitude more info. www.biorxiv.org/content/10.6...

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Reposted by Roman Tsukanov

Huisken lab @huiskenlab.bsky.social · 25/09/2026

Roman’s article in Laborpraxis explores microfluidics for multiplexed super-resolution imaging and its potential integration with Flamingo (in German): tinyurl.com/laborpraxis @romantsukanov.bsky.social #Flamingo #microfluidics #SuperResolution #microscopy #DNAPAINT #multiplexing

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Huisken lab @huiskenlab.bsky.social · 09/09/2026

Flamingo at #DZG2026 in Münster: Torben presents cleared tissue imaging of crustacean heart #morphology. @tgoepel.bsky.social @morphonews.bsky.social #Flamingo #LSFM #light-sheet

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Huisken lab @huiskenlab.bsky.social · 07/09/2026

Shape the future of light: PhD opportunities in photonics in the Huisken lab. Excellent research network. Apply through the Max Planck School of Photonics. Deadline 1 Dec 2026. www.photonics.school/ #LSFM #lightsheet #Flamingo

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Felipe Opazo @opazo.bsky.social · 04/09/2026

This new paper 🥂, just published in ACS Nano @pubs.acs.org s.acs.org, needed physicists, chemists, and biochemists in the same room! 🤓 Running out of colors in your #microscopy experiments? We developed #NanoFLex, which encodes protein identity by leveraging #nanobodies and #fluorescence lifetime

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Huisken lab @huiskenlab.bsky.social · 28/08/2026

Do wild-caught embryos develop in the same way as embryos cultured in the lab? This summer, Beke and Mette visited Luis at IMEV in Villefranche-sur-Mer, France, to start exploring this question in the marine annelid Platynereis dumerilii. #Platynereis #annelid #Flamingo #lightsheet #cell-lineage

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Roman Tsukanov @romantsukanov.bsky.social · 28/08/2026

#FluorescenceFriday ⚔️ DNA-PAINT vs self-blinking dSTORM, with #Vimentin as the benchmark structure. PAINT: tunable, multiplexable, almost no bleaching. SB-dSTORM: fast, buffer-independent, user-friendly, ExM-friendly. So who takes the belt? 🤼 The fight is on. 😄

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Roman Tsukanov @romantsukanov.bsky.social · 27/08/2026

New publication alert 🚨 Our Nano Letters paper on self-blinking dyes with nanobodies for robust SMLM is now Open Access! pubs.acs.org/nalefd/artic... Commercial Nb–JF635b probes are available from @nanotag.bsky.social. Joint effort of amazing collaborators, inspired by the great @opazo.bsky.social

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Huisken lab @huiskenlab.bsky.social · 13/08/2026

Huisken Lab outing to watch the total solar eclipse!

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Roman Tsukanov @romantsukanov.bsky.social · 07/08/2026

Had a fantastic time at #iPoLS 2026 @lmu.de in Munich! I really enjoyed presenting our #Flamingo project, exchanging ideas with colleagues, and catching up during the social events. Many thanks to the iPoLS and CeNS teams for the excellent organization! @huiskenlab.bsky.social

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Huisken lab @huiskenlab.bsky.social · 28/07/2026

Jan and Paul are back at MBL with a Flamingo microscope for the Zebrafish Development and Genetics course! Two weeks of exciting imaging sessions and zebrafish science are now underway. @mblscience.bsky.social #LightSheet #LSFM #PortableMicroscope #Flamingo #zebrafish

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Huisken lab @huiskenlab.bsky.social · 12/05/2026

PhD opportunity in Huisken lab with Zgierski-Johnston lab @uniklinik-fr.bsky.social. Topic: Multiscale Structural Imaging of Cardiac Conduction: Linking Interstitial Remodeling to Arrhythmia at Sub-Cellular Resolution. Deadline 7 June 2026. #LSFM #lightsheet #bioimaging #engineering #biophysics

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Huisken lab @huiskenlab.bsky.social · 14/03/2026

Honored to have two images from our lab selected among the Top 5 Research Images of the Year in Göttingen 🎉 The images will be exhibited in Forum Wissen until 10 April 2026. www.forum-wissen.de/event/resear... #ForumWissen #ScienceIsAlsoArt

forum-wissen.de

Research Images of the Year! Opening and Exhibition – Forum Wissen

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Uni Göttingen @uni-goettingen.de · 05/03/2026

How are components in cells organized? It's a huge challenge for science to visualize this! So researchers developed a microfluidics system to make high-resolution microscopy easier, more reproducible and accessible: www.uni-goettingen.de/en/3240.html... #ACSNano: pubs.acs.org/doi/10.1021/...

Image shows some of the researchers from the international research team involved in this development: From left to right: Dr Samrat Basak mastering the new generation of microfluidics system; Kim-Chi Vu in process of preparation of specialized muscle cells of the heart; Dr Roman Tsukanov in the optical/microfluidics lab. They are all shown in action in the laboratories engaged in different aspects of developing and using the system.
Photo: Samrat Basak, Kim-Chi Vu, Roman Tsukanov

A photo showing the system itself – with many buttons, wires, tubes and components. This shows the compressed-air-driven microfluidics system tailored for multiplexed super-resolution microscope developed by the research team to provide accessible, cost-efficient, high-quality imaging of cells, including fragile biological samples. Image thanks to Roman Tsukanov

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BIOspektrum @claudialudy.bsky.social · 04/03/2026

Ein internationales Team hat ein Mikrofluidik-System entwickelt, das hochaufgelöste Mikroskopie einfacher und reproduzierbarer macht. doi.org/10.1021/acsn... @joergenderlein.bsky.social @romantsukanov.bsky.social @uni-goettingen.de Bild: © Basak S et al., ACS Nano, DOI: 10.1021/acsnano.5c18697

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Felipe Opazo @opazo.bsky.social · 04/03/2026

New preprint out! In this study, we introduce NanoFLex, a strategy that combines #HaloTag variants with #nanobodies -based immunolabeling to enable rapid, OneStep-IF #lifetime #multiplexing. Possible due to SmartSecondaries fused to #HaloTag from @nanotag.bsky.social: www.biorxiv.org/content/10.6...

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Huisken lab @huiskenlab.bsky.social · 07/02/2026

New Huisken lab member: We’re excited to welcome Roman Tsukanov (@romantsukanov.bsky.social)! With expertise in super-resolution microscopy using DNA-PAINT, Roman will combine this technology with light sheet fluorescence microscopy. Exciting times ahead! #SuperResolution #DNApaint #lightsheet #LSFM

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Roman Tsukanov @romantsukanov.bsky.social · 07/02/2026

Beyond excited to join @huiskenlab.bsky.social! And thanks to the dream team for such a warm welcome! 🦩🦩🦩

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Reposted by Roman Tsukanov

Felipe Opazo @opazo.bsky.social · 22/12/2025

✨ Blinking #nanobodies that work for single-molecule localization 🔬 Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!

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Roman Tsukanov @romantsukanov.bsky.social · 10/11/2025

🧬 New paper out! Thrilled to contribute to our study on CaV1.3 channel clusters in cardiac myocytes using DNA-PAINT (4 nm loc. precision!) revealing flexible (not rigid) cluster organization. 👏 Great work by Niko Schwenzer, @samratb.bsky.social & team! 👉 www.sciencedirect.com/science/arti...

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Reposted by Roman Tsukanov

NanoTag Biotechnologies @nanotag.bsky.social · 30/10/2025

This #Halloween 🦙🧛‍♂️ Alpacula brewed up #SMLM treat! No more horror stories of no blinking & black holes ⚫️🔬Our single-domain anti-BOOdies 👻 #FluoTags and #SmartSecondaries now glow with self-blinking JF635b✨, delivering frightfully precise and simple #dSTORM imaging. 👉 bit.ly/4ffIkdB

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Roman Tsukanov @romantsukanov.bsky.social · 15/10/2025

We present a versatile microfluidics platform that makes multiplexed super-resolution imaging more accessible, reproducible, and high-throughput. 👉 BioRxiv: www.biorxiv.org/content/10.1... #SuperResolution #DNApaint #Microfluidics #SMLM #OpenScience #multiplexing

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Christophe 🔬 Leterrier @christlet.bsky.social · 28/09/2025

Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...

rizzoli-lab.de

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Roman Tsukanov @romantsukanov.bsky.social · 23/08/2025

🚨 New preprint update! 🚨 We introduce Confocal MIET-PAINT — extending our 3D nanoscopy method with: ✨ High multiplexing capacity ✨ Isotropic nanometer-scale resolution (lateral + axial) ✨ Compatibility with custom & commercial confocal SMLM equipped with FLIM www.biorxiv.org/content/10.1...

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Kristina @jekristina.bsky.social · 07/03/2025

To anyone who were excited for the release of SUM-PAINT, we now published a detailed protocol on to how replicate it in your hands! Check it out here: doi.org/10.1016/j.xp...

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SMLMS 2025 @smlm-symposium.bsky.social · 01/02/2025

Our invited speaker list is now online and we hope that your are as excited as we are! 🤗

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Roman Tsukanov @romantsukanov.bsky.social · 31/01/2025

Thrilled to share our latest review paper, "Advanced Fluorescence Lifetime-Enhanced Multiplexed Nanoscopy of Cells", co-authored with @samratb.bsky.social, now published in Methods in Microscopy! 🚀✨ Check it out here: www.degruyter.com/document/doi... #FLIM #SMLM #FLPAINT #FLSMLM #MIETPAINT

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