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Richard Smeyne

@rjsmeyne.bsky.social
662 followers 101 following 83 posts

Neuroscientist studying Parkinson’s disease, viruses in neurodegenerative brain disorders and role of isolation on the brain. Director of a Parkinson’s Foundation Center of Excellence. Caretaker to one Newfoundland and one Labradoodle. Opinions my own.

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Reposted by Richard Smeyne
Tim Mosca (he/him) @drosophilosophy.bsky.social · 10/09/2026
What an absolute and utter JOY it was to kick off our seminar series with @eisch.bsky.social! An absolutely amazing scientist, delightful human, and enthusiastic supporter of all things. If she's not on your seminar list, you need to put here there! Thanks for making the journey over the river. :)
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TogetherForSharon® @togetherforsharon.bsky.social · 05/09/2026
Q & A with Sharon's son, George. Episode 294 Special Guest: Richard Jay Smeyne, Ph.D: The Role of Viruses In Parkinson’s Disease Research. youtu.be/wKx8tjy0Ezg TogetherForSharon® In memory of my mother, Sharon to voice awareness & hope for a Parkinson's Disease cure.
youtu.be
Q & A with Sharon's son, George. Episode 294 Special Guest: Richard Jay Smeyne, Ph.D
YouTube video by TogetherForSharon®
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Reposted by Richard Smeyne
Dovewoman 💙 🇺🇦 💙 @dovewoman.bsky.social · 04/07/2026
YES!!!
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Richard Smeyne @rjsmeyne.bsky.social · 29/05/2026
Our review article on discussing the neuroprotective role of exercise in Parkinson’s disease is now published. This was an article supporting the Smeyne lab’s recent Plenary Session at the World Parkinson’s Conference. journals.sagepub.com/doi/epub/10....
journals.sagepub.com
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
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Reposted by Richard Smeyne
Tim Mosca (he/him) @drosophilosophy.bsky.social · 10/04/2026
Congratulations to Dr. Adam Marc, the latest minted PhD from Jefferson Neuroscience! He did lovely work in the Hahn and Borgmann-Winter labs on proteomics and schizophrenia and marvelously defended his thesis today!
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Richard Smeyne @rjsmeyne.bsky.social · 31/03/2026
A podcast I did previewing my Plenary talk at this years World Parkinsons Congress was just released. The podcast is called Hear! Here! Parkinson’s and originated in Norway. It us co hosted by Eli Pollard and Edgar Valdmanis. It can be heard at www.podbean.com/ew/pb-sdvz8-....
podbean.com
Episode 32: Richard Smeyne, PhD, Professor and Chair of the Department of Neuroscience at Thomas Jefferson University
On this episode of the Hear, Here Parkinson’s Podcast, we’re joined by Richard Smeyne, PhD — Professor and Chair of the Department of Neuroscience at Thomas Jefferson University. Dr. Smeyne dives into...
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Richard Smeyne @rjsmeyne.bsky.social · 11/11/2025
All ready for 3 days of exciting talks and discussions with our colleagues from Rome and Tel Aviv on topics ranging from Parkinson’s disease, ALS, stroke, epilepsy and immunology.
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Richard Smeyne @rjsmeyne.bsky.social · 23/10/2025
I just had the great honor of speaking with George Ackerman whose advocacy for Parkinson's disease has been tremendous. Our conversation about the role of viruses and PD on his TogetherFor Sharon podcast is available on Spotify. open.spotify.com/episode/4ZSJ...
open.spotify.com
Q & A with Sharon's son, George. Episode 294 Special Guest: Richard Jay Smeyne, Ph.D: The Role of Viruses In Parkinson’s Disease Research.
Spotify video
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Richard Smeyne @rjsmeyne.bsky.social · 18/10/2025
@raskin.house.gov giving a great and inspirational speech at Philadelphia’s No Kings rally. People from Independence Hall to the Constitution Center.
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Richard Smeyne @rjsmeyne.bsky.social · 18/10/2025
Appropriate place to end the Philadelphia No Kings march
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Richard Smeyne @rjsmeyne.bsky.social · 22/07/2025
Our paper discussing templating of alpha-synuclein and how over expression of monomeric (normal) forms of this protein can induce misfolding and induce SNpc DA neuron death was just published in Scientific Reports. nam10.safelinks.protection.outlook.com?url=https%3A...
nam10.safelinks.protection.outlook.com
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Reposted by Richard Smeyne
Danielle Beckman @daniellebeckman.bsky.social · 01/07/2025
Very honored to have given this Rising Star interview, where I could talk a bit about myself, my research, my passion for microscopy, and my dream to help find a cure for #LongCovid one day 💔 Link for the full interview: short-link.me/123uR Press release: www.eurekalert.org/news-release...
eurekalert.org
Brazilian neuroscientist reveals how viral infections transform the brain through microscopic detective work
Dr. Danielle Beckman's innovative research at the California National Primate Research Center demonstrates how viral infections disrupt brain homeostasis, leading to neuroinflammation and cognitiv...
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Richard Smeyne @rjsmeyne.bsky.social · 14/06/2025
On this Flag day, let’s remember that this country, founded by immigrants, is made great by the rainbow of people and opinions that strive for a more perfect union. Patriotism is not owned by one group and despite efforts at this small blip in time never will be.
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Richard Smeyne @rjsmeyne.bsky.social · 23/05/2025
Congratulations to 4 of our @ParkinsonDotOrg Center of Excellence movement disorder physicians, Drs Tsao-Wei Liang, Daniel Kremens and Jeffrey Ratliff (neurology) and Ashwini Sharon (neurosurgery) on being named 2025 top docs by Philadelphia magazine.
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Tim Mosca (he/him) @drosophilosophy.bsky.social · 21/05/2025
Congratulations Jefferson JCLS Class of 2025! Proud of all our Neuroscience graduates and their accomplishments on the road to their PHD, MD, and MS degrees! What a wonderful group of new scholars!! Mazel Tov!
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Richard Smeyne @rjsmeyne.bsky.social · 21/05/2025
Congratulations to the 2025 Department of Neuroscience graduating class. From L to R: Richard Smeyne, PhD, Professor and Chair, Hanni Jafri, MD, PhD (class of 2025, Dalva lab), Matthew Dalva, PhD (currently, Professor, Tulane University),
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Reposted by Richard Smeyne
Science Magazine @science.org · 25/04/2025
Jeffery Taubenberger, who gained fame for unearthing samples of the 1918 flu virus, and ultimately sequencing its entire genome, has been named acting director of the NIAID, Science has learned. scim.ag/3EzzUBo
scim.ag
Researcher of 1918 flu virus takes over NIAID
Jeffery Taubenberger becomes acting director of NIH’s second largest institute
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Richard Smeyne @rjsmeyne.bsky.social · 23/04/2025
Our paper examining the role of SARS-CoV-2 infection and its link to the development of Parkinson's disease has been published online in npj Parkinsons's disease. The article is open access. rdcu.be/ei1I6.
rdcu.be
Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection
npj Parkinson's Disease - Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection
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Stacey Schultz-Cherry @ssclabquips.bsky.social · 19/03/2025
We are excited to announce the next Journal of Virology seminar series will be live streamed on March 28 at 11 am Central Time. The paper to be presented is journals.asm.org/doi/10.1128/... by Dr. Christine Marizzi and her group asm.org/Biographies/...
journals.asm.org
Detection of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in New York City | Journal of Virology
While surveillance programs for avian influenza viruses are often focused on migratory routes and their associated stop-over locations or commercial poultry operations, many bird species—including mig...
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Richard Smeyne @rjsmeyne.bsky.social · 15/03/2025
I don’t normally post about politics and I say this as an older white male. We need to get rid of this older generation of Dems. We need new vigor to fight for our beliefs. The current admin will keep winning because Crazy has a lot of Energy.
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Richard Smeyne @rjsmeyne.bsky.social · 28/02/2025
Congratulations to our labs latest PhD graduate, Debotri Chatterjee who successfully defended her thesis entitled “Induction of Parkinsonism Pathology by Different Strains of SARS-CoV-2 in mice”. Now onto the final 2 years of medical school.
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Chengyuan Wu, MD, MSBmE @chenwumd.bsky.social · 26/02/2025
Intracranial electrode bending is underrecognized but not random—it correlates with brain stiffness interfaces. Our study shows MR elastography can predict deviations, challenging the idea that bending is inevitable. 🔗 Read the full article here: journals.lww.com/onsonline/ab... #DBS #stereotaxy
journals.lww.com
Deep Brain Stimulation Electrode Deviations are Associated... : Operative Neurosurgery
tion, an estimated 3% to 8% of patients still require revision surgery to address suboptimal electrode placement. DBS electrode deviation may occur at mechanical tissue interfaces, with denser interna...
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Richard Smeyne @rjsmeyne.bsky.social · 23/02/2025
Using your wealth for the betterment of mankind. www.forbes.com/sites/phoebe...
forbes.com
Sergey Brin’s $2 Billion Quest To Tackle Parkinson’s, Bipolar Disorder And Now Autism
The Google cofounder has donated more than $1.5 billion to Parkinson’s research. Now, as he takes on autism, he’s also investing in startups that might help.
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Amelia Eisch 🧪🧠👩‍🔬 🐁 @eisch.bsky.social · 22/02/2025
Updated flyer for the Philly Friday March 7 @standupforscience.bsky.social science protest, now w/ alt text & a slightly earlier time. Pls mark those calendars, make those signs & share widely #ScienceIsForEveryone #RestThenResist #CallYourRepresentatives #GoBirds #FlyScienceFly
A promotional flyer for 'Stand Up For Science 2025' featuring the Statue of Liberty in light blue against a blue background. The statue holds a torch with a yellow flame. Red banners contain white text announcing the event details: March 7, 2025 at Philadelphia City Hall at 11 AM. The flyer includes the tagline 'SCIENCE IS FOR EVERYONE' and directs viewers to find their local rally site at standupforscience2025.org. The design combines patriotic imagery with bold, modern typography in red and white.
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Richard Smeyne @rjsmeyne.bsky.social · 12/02/2025
Listening to Super Bowl champion and leader in community activism Malcolm Jenkins at Jefferson’s Salutes Martin Luther King Jr’s vision.
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Richard Smeyne @rjsmeyne.bsky.social · 10/02/2025
Nothing else needs to be said.
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Richard Smeyne @rjsmeyne.bsky.social · 06/02/2025
Our lab is looking for a self motivated postdoc to examine the role of infections in the brain, with a particular focus on induction and progression of parkinsonian pathology. The ideal candidate will have experience in immunology/virology. Although a background in neuroscience will be helpful.
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Richard Smeyne @rjsmeyne.bsky.social · 02/02/2025
I’m 65 years old and still Get excited when I look up In the sky and can see Mars, Saturn and Jupiter.
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Richard Smeyne @rjsmeyne.bsky.social · 26/01/2025
Fly Eagles Fly. E-A-G-L-E-S. Great for the city. Broad Street by Jefferson is a sea of happy humanity.
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Richard Smeyne @rjsmeyne.bsky.social · 24/01/2025
Had a delightful in person reunion with @ssclabquips.bsky.social in Philly for her seminar examining risk factors for influenza infection. Discussions will hopefully lead to a new collaboration on neuro effects of astrovirus.
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Richard Smeyne @rjsmeyne.bsky.social · 16/01/2025
Had a valuable zoom talk with @daniellebeckman.bsky.social on future collaborations examine the role of viruses in the etiology and progression of Parkinson’s disease. Lots of good ideas bantered back and forth. Hopefully will lead to new and exciting research.
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Danielle Beckman @daniellebeckman.bsky.social · 12/01/2025
So you want to be a scientist? Advice to the young from pioneering astrophysicist Cecilia Payne-Gaposchkin, who discovered that stars were made primarily of hydrogen, illuminating for the first time the chemical composition of the cosmos. 🧪
Quote by Cecilia: Do not undertake a scientific career in quest of fame or money. There are easier and better ways to reach them. Undertake it only if nothing else will satisfy you; for nothing else is probably what you will receive. Your reward will be the widening of the horizon as you climb. And if you achieve that reward you will ask no other.
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Richard Smeyne @rjsmeyne.bsky.social · 12/01/2025
Today is the first Philadelphia Flyers game for my Granddaughter Sofia.
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Prof Malú Gámez Tansey @malutansey.bsky.social · 10/01/2025
Day 2 Session 6 on #genes x #metabolism #environment with Kiran Thakur Keenan Walker Badri Vardarajan Caghan Kizil & Guo Luo
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Prof Malú Gámez Tansey @malutansey.bsky.social · 10/01/2025
Day 2 Session 5 #TCB2025 #innovative approached to Antigen-Specific T cell #discovery for #nextgen #immunotherapies with Ning (Jenny) Jiang Giacomo Oliveira Moshen Khosravi Maharlooei & Suna
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Prof Malú Gámez Tansey @malutansey.bsky.social · 10/01/2025
Day 2 Session 7 #ImmuneDynamics at #BarrierTissues #gut_brain in #neurodegeneration with Michal Schwartz Soyong Hong Sandro Da Mesquita Elizabeth Bradshaw & Ryan Hobson
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Prof Malú Gámez Tansey @malutansey.bsky.social · 09/01/2025
hair @WassimElyaman wants you to get ready for this Industry Round-Table at #TCB2025 livestream on WassimElyaman on X @Merck, @SanofiUS, @MontaiHealth, @LeahSibener, @mekapk_kennedy discussing drug discovery & immunotherapy in 🧠✨ #NeuroImmunology #TCB2025Live
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Prof Malú Gámez Tansey @malutansey.bsky.social · 09/01/2025
Session 3 #peripheralImmune in #neurodegeneration with @rransohoff @MatheoudD @UFHealth Catherine Flores @YaleMed Le Zhang @DallinDressman
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Prof Malú Gámez Tansey @malutansey.bsky.social · 09/01/2025
Session 2 #TCB2025 #peripheralimmune #mechanisms in #neurodegeneration with @SaligramaLab @HarmsLab Ronald Libiau & @malutansey.bsky.social
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Prof Malú Gámez Tansey @malutansey.bsky.social · 09/01/2025
Kicking off 2025 with #TCB2025 tcellsbrain.org today in #NYC @Columbia 🤓💪🏼 🧠 🩸
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Richard Smeyne @rjsmeyne.bsky.social · 09/01/2025
Great morning session at T-Cells in the brain conference at Columbia University. Love these small intense meetings with lots of interactions.
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Prof Malú Gámez Tansey @malutansey.bsky.social · 09/01/2025
Session 1 #TCB2025 #immunedysregulation in #neurodegeneration w David Hafler Rani Sarkis Wassim Elyaman & Maria Mittelbrunn
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Richard Smeyne @rjsmeyne.bsky.social · 08/01/2025
On my way to NYC for T-Cells in the Brain symposium at Columbia University. Let’s just combine the complexities of the nervous system with the immune system for 2 days of fun.
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Richard Smeyne @rjsmeyne.bsky.social · 20/12/2024
I am giving a talk at our translational research retreat for our Farber Neurological Institute this afternoon on the role of viruses in Parkinson’s disease. Historically I link to the 1918 flu pandemic. Regarding mitigation, nothing has changed (look at dates on slide).
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Richard Smeyne @rjsmeyne.bsky.social · 20/12/2024
Two papers accepted with moderate revisions this week. An early holiday present was that the reviewers of both papers gave insightful and helpful comments that will in the end make them better. Usually I complain (b**tch) about the comments but spent our holiday lunch complementing their comments.
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Kai Kupferschmidt @kakape.bsky.social · 06/12/2024
If an #H5N1 pandemic starts tomorrow or in three months, there will be little mystery as to how it happened. The conditions are all there. They have been for a while. So in some ways the more interesting question to me at the moment is: Why aren’t we in a pandemic yet? Story here, 🧵 to come: 🧪#IDSky
science.org
Why hasn’t the bird flu pandemic started?
Some scientists examining mutations found in H5N1 viruses fear major outbreak is imminent but others says pathogen remains unpredictable
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Richard Smeyne @rjsmeyne.bsky.social · 03/12/2024
Our preprint discussing the parkinsonian impact of two strains of COVID, how this is affected by vaccination and how carrying a LRRK2 mutation worsens pathology and escapes vaccine protection has just posted. The implications of this on public health are significant. biorxiv.org/cgi/content/...
biorxiv.org
Environmental exposures and familial background alter the induction of neuropathology and inflammation after SARS-CoV-2 infection.
Basal ganglia disease has been reported as a post-infection sequela of several viruses, with documentation of this phenomenon from the H1N1 Spanish flu to the recent COVID-19 (SARS-CoV-2) pandemic. SA...
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Richard Smeyne @rjsmeyne.bsky.social · 27/11/2024
Heads up for our preprint of our studies showing effects of alpha and omicron strains of SARS-CoV-2 on the basal ganglia and how the immune response to this infection is dysregulated in mice carrying the G2919S LRRK2. Also LRRK2 mice do not fully respond to mRNA vaccine but do to a protein vaccine.
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Richard Smeyne @rjsmeyne.bsky.social · 26/11/2024
Hockey fights cancer night across the NHL. Here @philadelphiaflyers.bsky.social vs Las Vegas Golden knights.
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Richard Smeyne @rjsmeyne.bsky.social · 26/11/2024
Had a nice reunion with Dr Cory Abate-Shen from Columbia University for her lecture on prostate cancer biology. We were postdocs together at the Roche Institute for Molecular Biology in 1990. Haven’t aged a day.
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