Genome-wide association studies and rare-variant burden tests reveal complementary aspects of trait biology.

Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...

Research by the Psychiatric Genomics Consortium (PGC) has advanced the discovery of common and rare genetic variations that contribute to the susceptibility to many psychiatric disorders and neurodeve...

What Michelangelo, a Nobel Laureate, and a PhD Meltdown Taught Me about Research Questions

This study explores the dynamics of adolescent depression through the lens of network temperature, a novel concept in psychological symptom networks. Researchers observed a decrease in network tempera...

How I found my way out of depression, thanks to the writings of the English priest who brought Buddhism to the West

Pervasive genetic overlap across human complex traits necessitates developing multivariate methods that can parse pleiotropic and trait-specific genetic signals. Here, we introduce Genomic Network Ana...

This is a keynote I gave at the DPK congress in Berlin 2024, a large conference primarily attended by psychotherapists. I want to thank them—and especially T...