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Adrienne Oneil

@profadrienneoneil.bsky.social
1.2K followers 713 following 49 posts

Professor, Behavioural Scientist, Food & Mood Centre, Deakin University 🧠❤️🥦🥑🫒🍎🏋️🏃‍♀️ Music & Sports Lover Brisbane lions fan 💛❤️💙 Myalgic Encephalomyelitis/Long Covid advocate & Lived Experience consultant

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Adrienne Oneil @profadrienneoneil.bsky.social · 22/05/2025
www.hcplive.com/view/rapamyc... Now culminating in a clinical trial led by the Simmaron lab in NYC
hcplive.com
Rapamycin Improves PROMs in Patients With ME/CFS in Early Trial
Statistically significant improvements were seen in BAS, MFI, SF-36 subscores, SSS fatigue, disrupted sleep. PEM, and orthostatic intolerance.
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Adrienne Oneil @profadrienneoneil.bsky.social · 22/05/2025
Keeping a keen eye on the therapeutic potential of rapamycin-an immunomodulator 1st approved as a prophylactic against organ rejection. Two new pilots show that: 1) it didn’t penetrate the BBB but improved inflammatory biomarkers and 2) fatigue, cognition in #MECFS www.nature.com/articles/s43...
nature.com
Rapamycin treatment for Alzheimer’s disease and related dementias: a pilot phase 1 clinical trial - Communications Medicine
Gonzales et al. conducted an open-label phase 1 clinical trial of rapamycin for mild cognitive impairment and dementia due to Alzheimer’s disease. Rapamycin is not detected in cerebrospinal fluid befo...
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Communications Medicine @commsmed.nature.com · 21/05/2025
🚨 NEW RESEARCH! ⚕️ 🩺 DeLong et al. find associations between physical #multimorbidity and #depression using the UKBiobank data. bit.ly/4kz23rD #MentalHealth #PhysicalHealth
bit.ly
Cluster and survival analysis of UK biobank data reveals associations between physical multimorbidity clusters and subsequent depression - Communications Medicine
DeLong et al. investigate several clustering techniques to identify patterns of physical multimorbidity. They find several clusters which align to known body systems and use survival analyses to determine which clusters are most associated with depression.
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Adrienne Oneil @profadrienneoneil.bsky.social · 10/05/2025
Amazing! I’ll be printing this out and taking with me to all appointments
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Adrienne Oneil @profadrienneoneil.bsky.social · 06/05/2025
Done! Thank you for using your previous energy for advocacy 🌺
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Adrienne Oneil @profadrienneoneil.bsky.social · 30/04/2025
Wow congrats on an amazing outcome! I hope she is the first of many who benefits from CRISPR
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Adrienne Oneil @profadrienneoneil.bsky.social · 26/04/2025
So tragic. I hope she is at peace now 🌺
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Tom Kindlon @tomkindlon.bsky.social · 22/04/2025
A housing project specifically for people with severe ME/CFS, including 24-hour assistance, is being planned in Neunkirchen-Seelscheid Info in German sozialhummel.de/wohnprojekt-... Some info & discussion in English www.s4me.info/threads/hous... Image from Science for ME update #MEcfs #SevereME
Germany
A housing project specifically for people with severe ME/CFS, including 24-hour assistance, is being planned in Neunkirchen-Seelscheid . A developer, in collaboration with Sozialhummel, plans to build barrier-free apartments that are optimally tailored to the needs of people with severe ME/CFS. Interested parties can join a waiting list.
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Adrienne Oneil @profadrienneoneil.bsky.social · 16/04/2025
Daisy having the best day ever, scoring a slice of pepperoni on her walk 🍕
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Katie Klocksin, by the wayside @katieklocksin.bsky.social · 08/04/2025
NIH observational study finds that one of every 22 covid infections causes myalgic encephelomyelitis: www.livescience.com/health/coron...
livescience.com
1 in 22 COVID survivors develop debilitating chronic syndrome
A study suggests that catching COVID-19 significantly raises the risk of developing ME/CFS (formerly called "chronic fatigue syndrome"), a typically lifelong condition that can be debilitating.
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Danielle Beckman @daniellebeckman.bsky.social · 06/04/2025
My favorite from today. #HandsOff #HandsOff2025
A person wearing a respirator and a sign that reads: Science keeps your dumb ass alive
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Danielle Beckman @daniellebeckman.bsky.social · 04/04/2025
This whole conversation about #LongCovid... Research published in Nature Medicine estimates Long Covid has an annual economic impact of approximately $1 trillion—equivalent to about 1% of the global economy. www.nature.com/articles/s41...
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Adrienne Oneil @profadrienneoneil.bsky.social · 29/03/2025
Thanks the Age for handing my story with care and Congrats Dr Armstrong & team on this exciting finding. This research isn’t possible without Open Medicine Foundation funding #MECFS research where NHMRC won’t. Newspaper👇 www.theage.com.au/national/vic... Research👇 www.nature.com/articles/s43...
theage.com.au
It took 11 years for Adrienne’s illness to be diagnosed. A new computer model could change everything
Chronic fatigue syndrome is notoriously difficult to diagnose, but a new computer-assisted model can predict it with 85 per cent accuracy.
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BK. Titanji @boghuma.bsky.social · 23/03/2025
99.4% of new drugs approved by the FDA are the product of NIH funded research. Remember this every time you see another headline on the NIH funding cuts. It will directly impact YOU. #ScienceNOTSilence
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Adrienne Oneil @profadrienneoneil.bsky.social · 21/03/2025
Sending hugs from Australia 💪
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Adrienne Oneil @profadrienneoneil.bsky.social · 21/03/2025
It was a fabulous session! Thank you both for being such fierce advocates for rigorous ME/CFS & LC research
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Adrienne Oneil @profadrienneoneil.bsky.social · 20/03/2025
Oh Anastasia, I hope he’s ok. Thinking of you and Harris x
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Danielle Beckman @daniellebeckman.bsky.social · 15/03/2025
#LongCovidAwarenessDay2025
Amy on twitter: I've been 90-99% bedbound for nearly 3.5 years. People say "it's the vax" - I never got the vax. People say "it's laziness" - I used to be an athlete.
No more excuses.
We need help NOW.
#5YearsLongCovid #HalfADecadeOfNeglect #LongCovidAwarenessDay2025
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Adrienne Oneil @profadrienneoneil.bsky.social · 12/03/2025
So so cool!! Yay for medical science!
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Adrienne Oneil @profadrienneoneil.bsky.social · 09/03/2025
Forest therapy 😍🌺🐨🌈
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Adrienne Oneil @profadrienneoneil.bsky.social · 06/03/2025
Ping @ameliamcg.bsky.social
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Adrienne Oneil @profadrienneoneil.bsky.social · 03/03/2025
“My average (long COVID) patient is previously very fit, very successful, and desperate to get back to normal life,” he says. “The people I’m looking at are actually incredibly motivated, the movers and shakers of society, and we lose them to our detriment.” 😭😭💔💔
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Danielle Beckman @daniellebeckman.bsky.social · 25/02/2025
My friends are dying. People are dying of #LongCovid and #MECFS while society keeps ignoring their existence. Rest in peace, Faraz. Sorry we failed you.
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Adrienne Oneil @profadrienneoneil.bsky.social · 25/02/2025
New to behavioural mental health trials and unsure how to assess and monitor harms? With MAGNET Clinical Trial Network, we have developed a “How To” guide with step by step recommendations & tips. We hope you find it helpful! #behaviouralscience #behavioralmedicine doi.org/10.1177/0004...
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Adrienne Oneil @profadrienneoneil.bsky.social · 19/02/2025
@jodieingles27.bsky.social @scartledge.bsky.social @sarahgauci.bsky.social 💔
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Adrienne Oneil @profadrienneoneil.bsky.social · 19/02/2025
Last night’s Australian Story following the lives of two people who lost their spouse to sudden cardiac arrest was so powerful. A reminder of the importance of the work we do in CVD research www.abc.net.au/news/2025-02... #suddencardiacarrest #cpr #cardiac
abc.net.au
Heartfelt | Col Clausen + Laura Aisbett
Follow the latest news headlines from Australia's most trusted source. Read in-depth expert analysis and watch live coverage on ABC News.
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Adrienne Oneil @profadrienneoneil.bsky.social · 16/02/2025
Great paper Sarah! #behaviouralscience #nutrition #cardiovasculardisease
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Robert Reich @rbreich.bsky.social · 15/02/2025
The irony of the richest man in the world almost single-handedly destroying an agency designed to help the world’s poor, so that the U.S. federal budget has more room for another giant tax cut for the richest man in the world and his pals, should not be lost on anyone. [Cartoon by Mike Luckovich]
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Adrienne Oneil @profadrienneoneil.bsky.social · 15/02/2025
Haha very happy to come to Sydney Anastasia! 🌺🤩
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Tom Kindlon @tomkindlon.bsky.social · 13/02/2025
More information on negative responses to Cochrane scrapping their plan to do a new review of exercise therapy for CFS Links: thesicktimes.org/2025/02/04/r... www.s4me.info/threads/s4me... Screenshot from latest Science for ME weekly update #MEcfs #CFS
More on Cochrane's actions (see December and January news)

The Sick Times "Really pissed off": Cochrane receives backlash from advocates and experts after abandoning ME/CFS review
Great article by David Tuller with a longer recap of the Cochrane saga. Two members of the writing team that was appointed by Cochrane to update the review provide comments:
Todd Davenport: "This experience has really showed me the extent of the political games behind this supposedly objective process of trying to synthesize studies"
Mary Dimmock: "We put a lot of work into doing this in good faith, and they just pulled it with no consideration for the patients"
Tuller concludes: ".. it appears that Cochrane’s actions are, from its perspective, irreversible. But unless it acts quickly to clean up this mess, the long-term damage to its reputation could be irreversible as well."
Article l Thread

Science for ME Complaints about republishing an outdated and flawed review as if it were a new review, and the failure to withdraw it
Trish Davis and Maree Candish, on behalf of the Science for ME committee, have submitted a detailed set of five complaints with supporting evidence. The submission concludes:
"We find these actions by Cochrane so clearly indefensible and the arguments so illogical that we can only conclude that senior editors and Trustees have given in to pressure from proponents of exercise therapy for ME/CFS. We ask Cochrane to take the following actions in order to restore its credibility and avoid further harm to patients."
Actions requested include removal of the 2024 version; an editorial note saying the review is outdated and should not be used for clinical care; standing firm against pressure from exercise proponents with vested interests; and re-opening the decision not to withdraw the 2019 review.
Complaint | Discussion thread
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Peter Morley ♿️ @petermorley.bsky.social · 12/02/2025
Thank goodness for the American Medical Association. Here is their YouTube page. Please share far and wide. Right now bird flu is spreading throughout our country and most people have no clue. Please stay updated and bookmark this page for your health and well-being. www.youtube.com/@americanmed...
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Adrienne Oneil @profadrienneoneil.bsky.social · 12/02/2025
Welcome!!! 🤗
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Krutika Kuppalli, MD FIDSA @krutikakuppalli.bsky.social · 08/02/2025
NIH doesn’t just support infectious disease research—it drives breakthroughs in cancer, childhood diseases, heart disease, diabetes & more. Thanks to NIH, we have: 💉 Cancer immunotherapy ❤️ Cholesterol-lowering statins 🩸 Insulin for diabetes Investing in NIH = investing in life-saving discoveries.
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Adrienne Oneil @profadrienneoneil.bsky.social · 07/02/2025
My veggie garden is going gangbusters! 🍎🍆🎃🍅
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Adrienne Oneil @profadrienneoneil.bsky.social · 03/02/2025
Summer sunset in Victoria, Australia after crazy storms last night
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Megan Ranney MD MPH @meganranney.bsky.social · 03/02/2025
Some NIH study sections for tomorrow have just been canceled. Who knows which of these grants would have led to the next life-saving invention. Who knows which scientists will throw in the towel bc of funding delays. Who can even begin to measure the impact of these reckless cancellations.😕🩺🧪🛟
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Adrienne Oneil @profadrienneoneil.bsky.social · 31/01/2025
Wow!! 🤯
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Adrienne Oneil @profadrienneoneil.bsky.social · 28/01/2025
This is a super scary - both for scientists relying on NIH funds and for patients awaiting scientific advances in treatments 😭
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Adrienne Oneil @profadrienneoneil.bsky.social · 02/01/2025
Not to mention the harm this paper has done in the time since it was published by concluding LC is strikingly rare in kids when they seemingly did not even understand what LC is. 😫
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Adrienne Oneil @profadrienneoneil.bsky.social · 16/12/2024
Here’s a summary of our recent CALM trial results showing lifestyle counselling with dietitians/EPs was non inferior to psychotherapy with psychs for low grade depression published in Lancet Regional Health. Thanks to Dr Deb Ashtree for the infographic! #lifestylepsychiatry #behaviouralscience
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Adrienne Oneil @profadrienneoneil.bsky.social · 03/12/2024
😭😭😭😭
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Adrienne Oneil @profadrienneoneil.bsky.social · 03/12/2024
Interesting trial of behavioural text messages for uptake of CVD medication refills in JAMA today Generic refill reminders; behavioral nudge refill reminders; nudge refill reminders + fixed-message chatbot did not differ from usual care #behavioralscience jamanetwork.com/journals/jam...
jamanetwork.com
Message Reminders to Improve Adherence to Chronic Cardiovascular Medications
This randomized clinical trial compares different text messaging strategies (generic refill reminders, behavioral nudge refill reminders, behavioral nudge refill reminders plus a fixed-message chatbot...
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Adrienne Oneil @profadrienneoneil.bsky.social · 03/12/2024
Can’t believe that was 4 years ago- time flies! It’s like the old meme of the PhD doc on a flight who cannot respond to a medical emergency but damn can we edit a conference abstract to within word limit in an emergency situation 😂
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Adrienne Oneil @profadrienneoneil.bsky.social · 02/12/2024
Haha she’s a classic! Thanks for the follow BJ- I’ve followed you and your work for many years
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Adrienne Oneil @profadrienneoneil.bsky.social · 01/12/2024
Grateful to Medical Journal of Australia Insight + mag for featuring this piece on the role of dietitians & exercise physiologists in managing mental health and our current opportunity for GPs to refer their patients to our national trial #behavioralscience insightplus.mja.com.au/2024/47/can-...
insightplus.mja.com.au
Can treating depression mitigate the excess cardiometabolic risk of people living with serious mental illness?
A national primary-care based trial is the largest ever to determine whether lifestyle therapy is
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Adrienne Oneil @profadrienneoneil.bsky.social · 29/11/2024
Awesome infographic from Meg Teychenne & team illustrating the various mechanisms linking physical activity to mental health 🏋️🏃‍♀️ Fulltext 📌 doi.org/10.1186/s129... #behaviouralscience #lifestylepsychiatry
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tamsin yeld into the void @68thmonkey.bsky.social · 25/11/2024
Latest study from OMF Australia looking at neuroinflammation, brain blood flow and hormones at the hypothalamus. At ethics approval stage, soon open to registration via studyME. #MECFS youtu.be/E8ahiEZcwik?...
youtu.be
Linking Brain Blood Flow, Neuroinflammation, Metabolism, and Hormones in ME, POTS, and Long COVID
YouTube video by Open Medicine Foundation - OMF
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Adrienne Oneil @profadrienneoneil.bsky.social · 21/11/2024
#behaviouralscience
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Adrienne Oneil @profadrienneoneil.bsky.social · 21/11/2024
Gee that’s good to know there are some GPs who will. Seems an outrageous oversight by the PBS
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Adrienne Oneil @profadrienneoneil.bsky.social · 21/11/2024
Thanks Rachel!
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