A personalized mRNA cancer vaccine succeeded in a late-stage melanoma study, results that could herald a new, powerful approach in oncology.

Phase I results show early promise for a vaccine designed to prevent pancreatic cancer in people at high risk of developing the disease.

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YouTube video by AdamGumby

YouTube video by AdamGumby

If the vaccine is effective in a late-stage trial, it would be “paradigm-shifting,” one expert said.

The HPV vaccine for cervical cancer has reduced the risk of dying from the disease before the age of 30 in England to almost zero, the first study of its kind showed Thursday.