iiinova — where your digital self keeps evolving

Will @popher.bsky.social · 9h

Almost no one has any real political power or influence as an individual, so it's really quite wild how many people choose to be dicks

Will @popher.bsky.social · 10h

So I'm trying to export data from chromeleon. It exports to .raw. But only if it includes MS data. But .raw can contain non MS data. However it can export to a chromeleon format .cmbx. which is actually an archive containing .raw files. Except those .raw files can't open in FreeStyle. Thermo wtf

Will @popher.bsky.social · 11h

I just heard someone ask about "queries", as in, questions or database calls... But I forgot the word and thought it was some cute group noun for LGBT folks. Queeries

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Reposted by Will

Carl T. Bergstrom @carlbergstrom.com · 11h

Now banned in California. I'd like to see the rest of the country follow.

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Will @popher.bsky.social · 12h

"Squish! Uh-uh! Cicero! Lipschitz"

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Will @popher.bsky.social · 13h

Its always fascinating what gets a 'top tier' journal paper. This is cool, obviously, but expansion MSI has been reported a few times before. Like this paper in Nature Comms in 2024 - www.nature.com/articles/s41... - achieved a 3-6x expansion ratio.

nature.com

Gel-assisted mass spectrometry imaging enables sub-micrometer spatial lipidomics - Nature Communications

Mass spectrometry imaging (MSI) is often limited by low spatial resolution. Here, the authors propose Gel-Assisted Mass Spectrometry Imaging (GAMSI), which enhances the spatial resolution of MALDI-MSI...

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Will @popher.bsky.social · 21h

I feel like I'm missing something with the deuterium story.. maybe it's because I'm used to looking at exact mass data and thinking about isotopes, but like... What's the part that everyone is very excited about?

Will @popher.bsky.social · 23h

Neat! It's also funny how different experiences would lead to this answer more or less quickly. Isotopes are neat

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Angela Sutton (she/her) @drangelasutton.bsky.social · 29/09/2026

The quality of mainstream meat in the US has been atrocious for years; expensive and bad. But it's only getting worse.

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I can't get over how beef prices went so high that no one could afford the $90 briskets, then the US imported tons of carcinogen-ridden beef from Argentina that would have been illegal a year ago and now grocery stores and fast food are advertising big deals on beef and no one is talking about it.

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Misread as, "genuinely thought we were good on Teams"

I'm so bemused why everyone is obsessed with commenting on how much they don't care about the number one song in the charts.

In the olden days you could move city, country, continent and escape your problems (or at least, change them). But thanks to the internet there is no escape.

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This is helpful because I haven't seen it yet lol

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Why is/was every sitcom for the last 15, 20 years a fake documentary?

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So Futurama had it's series finale, again. Bittersweet, everytime. A few nice callbacks.

At the same time as some uni offering a 'content creation' degree (media studies v2?), Edinburgh is shutting down 90 courses.

Lol ok so much wrong here

Rainier, St Helens, Adams and Hood.

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Do you think pilots tap the roof when theres a cop plane nearby?

Laura Howes @laurahowes.bsky.social · 28/09/2026

Reposted by Will

I think #chemsky has discussed before how NO-ONE should be feeding unpublished or proprietary data into public models. It really feels like that is worth reiterating.

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Pru @prufrockluvsong.bsky.social · 28/09/2026

Please stop calling me on my phone that's not what it's for

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Urvi @theurv.com · 28/09/2026

There were more men in a single documented gang rape at one school than the number of competitive trans athletes nationally. But I’ve heard a lot more politicians being asked about protecting girls from one of these scenarios and not another… I’ll let you guess which is which.

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Marisa Kabas @marisakabas.bsky.social · 28/09/2026

"See it, say it, sor---sorry they were arrested for fly tipping?"

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the cornell case has me thinking about christine blasey ford and how she so bravely testified in 2018 about how future supreme court justice brett kavanaugh had sexually assaulted her. i'm thinking about what i wrote at the time and how nothing has changed:

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Chris Geidner @chrisgeidner.bsky.social · 28/09/2026

The independent was good, once upon a time. Now it is a slop farm

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BREAKING: DOJ asks SCOTUS to erase trans people from the law in case over trans care in prison. Solicitor General John Sauer made the alarming, all-encompassing argument — previously covered at Law Dork — to the Supreme Court on Monday morning. Today, at Law Dork:

lawdork.com

Breaking: DOJ asks SCOTUS to erase trans people from the law in case over trans care in prison

Solicitor General John Sauer made the alarming, all-encompassing argument — previously covered at Law Dork — to the Supreme Court on Monday morning.

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Hotel carpet giving me top down proteomics sequence coverage vibes.

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Dave DiCello @davedicello.bsky.social · 28/09/2026

I suspect the artists intention was not a GOP Klansman. And yet...

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Last night was the 13th anniversary of the day that the Giant Rubber Duck arrived in #Pittsburgh, and honestly it was one of my favorite nights of photography. This was the only night that it wasn't parked by the fountain at the Point, creating some unique and fun images.

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hammancheez @hammancheez.bsky.social · 28/09/2026

Where are we at calling out LinkedIn posts for AI Slop chemical structure chemical structures, especially when it's advertising some software they claim is good at NMR structural elucidation

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GOP Consultants : what do you mean she just fucking tweeted it out

Marjorie Taylor Greene
We have not seen a caravan headed to the U.S.
southern border in several years, why now?
Oh yeah, there is an election coming and the
GOP needs to scare you into voting because
nothing else is working.

Anthony Aguero Live
Over 400 aliens predominantly from
Honduras entered Mexico on Thursday,
ready to make their way to the US southern
border ... Here's footage of the caravan.
Someone is incentivizing this movement, t ...

@mt ... . 1d

@Anth ... . 1d

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Kermit Murray @kkmurray.bsky.social · 28/09/2026

(ChemRxiv) Rapid chromatography combined with trapped ion mobility mass spectrometry for analysis of derivatized small molecules #MassSpecRSS

dlvr.it

Rapid chromatography combined with trapped ion mobility mass spectrometry for analysis of derivatized small molecules | ChemRxiv

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If you have a window seat you should not be boarding the plane last because you went to get a coffee.

I've only heard of one of these people lol

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In Stargate sg1 episode "2010" Carter is obviously no longer in the military (it doesn't exist anymore) and the president calls her "Dr Carter" and yes she has a PhD but she was a Major in the USAF and surely that takes higher precedence?

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I'm at the "tiktok wants you to cry" stage of the evening

Aparna Nair @disabilitystor1.bsky.social · 27/09/2026

Reposted by Will

I keep coming back to this clip against the background of AI companies infesting higher education. And I feel like I need to show this in class to students, for them to understand why not to trust these bastards

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Continuing the champagne and gummy bear pairing challenge, We've ended up here. Mildly surprised, my least favourite of the wines is ruinart

I asked the bartender what was better between the burger or the linguini. He told me to get the gyro. Lol ok then.