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Pauline M.L. Coulon

@pmlcoulon.bsky.social
99 followers 99 following 24 posts

Microbiology, Burkholderia, colony morphotype variation, ECR @AIMI

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Reposted by Pauline M.L. Coulon
Nature Portfolio @natureportfolio.nature.com · 10/06/2026
Robert Harcourt captured an image of Michael Doane, a marine biologist, collecting a microbiome sample from a whale shark off the coast of Western Australia. #SciArt
Robert Harcourt captured an image of Michael Doane, a marine biologist, collecting a microbiome sample from a whale shark off the coast of Western Australia.
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 05/06/2026
Excited to be attending #ASMicrobe in Washington, DC! Learn how multi-omics improves understanding of colony morphotype variation in B. pseudomallei and distinguishes true CMV from polyclonal infections. 📍 Poster Board: MECH-FRI-581 Thanks to the Australian ASM ECR International Travel Award.
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 01/05/2026
What a great reminder youtu.be/Zxg38eUL5IY?...
youtu.be
He changed science forever. He spoke with us on that, AI, Trump and immortality just before he died.
YouTube video by Scientific American
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 30/12/2025
I am excited to share that my fourth paper of 2025 is finally out. Perfect timing to conclude the year. journals.asm.org/doi/10.1128/...
journals.asm.org
Profiling of Burkholderia pseudomallei variants derived from Queensland’s clinical isolates | Microbiology Spectrum
Burkholderia pseudomallei (Bp), the causative agent of melioidosis, is endemic to Australia, Asia, Africa, and the Americas. It predominantly affects Indigenous populations and individuals suffering f...
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 30/12/2025
I am excited to share that my fourth paper of 2025 is finally out. Perfect timing to conclude the year. journals.asm.org/eprint/8YRDZ...
journals.asm.org
Profiling of Burkholderia pseudomallei variants derived from Queensland’s clinical isolates | Microbiology Spectrum
Burkholderia pseudomallei (Bp), the causative agent of melioidosis, is endemic to Australia, Asia, Africa, and the Americas. It predominantly affects Indigenous populations and individuals suffering f...
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 21/12/2025
Finally out in @PLOSONE! I would like to thank my co-authors and the reviewers for helping us improved the article. journals.plos.org/plosone/arti...
journals.plos.org
Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland
While investigating colony morphology variation within clinical isolates of Burkholderia pseudomallei (Bp) isolated from a single clinical infection, we identified two distinct strains (based on their...
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 21/12/2025
I have just read Prof E. Peter Greenberg latest editorial paper, explaining why he has been working on P. aeruginosa. That is very refreshing to hear how research is also impacted by interpersonal relationships and personal events. We should hear more about it. doi.org/10.1128/jb.0...
doi.org
Pseudomonas aeruginosa, my model for research on quorum sensing, biofilms, and opportunistic infections | Journal of Bacteriology
With encouragement from the Journal of Bacteriology Editor in Chief, George O’Toole, I have written this short essay in a style different than Journal of Bacteriology articles on model organisms. It i...
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 10/09/2025
🚨 New preprint out! Proud to share the first reported clinical case of polyclonal #melioidosis infection in QLD—also the first study applying integrative multi-omics at the bacterial level. 🧬 Time to advance diagnosis & build a multi-omics database!
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Reposted by Pauline M.L. Coulon
Will Smith @willpjsmith.bsky.social · 31/08/2025
Does your lab perform killing assays? TL;DR: we’ve identified a problem that can bias the outcome of killing assays, making antagonism look stronger than it really is. Adding a simple extra step can mitigate this bias!  Out now at #MicrobioJ www.microbiologyresearch.org/content/jour... 1/n
microbiologyresearch.org
Type VI secretion system activity at lethal antibiotic concentrations leads to overestimation of weapon potency
Competition assays are a mainstay of modern microbiology, offering a simple and cost-effective means to quantify microbe–microbe interactions in vitro. Here, we demonstrate a key weakness of this meth...
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Reposted by Pauline M.L. Coulon
Andreas Peschel @andreaspeschel.bsky.social · 23/08/2025
"What makes S. aureus such a difficult vaccination candidate?" Here are some answers:
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 13/08/2025
I am very excited to share our latest preprint on ⬇️
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Reposted by Pauline M.L. Coulon
Dr Sariqa Wagley @sariqawagley.bsky.social · 09/08/2025
Melioidosis in Asia-Pacific Nations: Expanding Boundaries but Unknowns Remain By Bart Currie and Ella Meumann doi.org/10.1111/resp...
doi.org
<em>Respirology</em> | APSR Respiratory Medicine Journal | Wiley Online Library
Click on the article title to read more.
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Reposted by Pauline M.L. Coulon
George O'Toole (he/him/his) @geiselbiofilm.bsky.social · 18/07/2025
A few days ago I had the chance to talk about our work on the gut-lung axis in cystic fibrosis as part of a webinar with The Scientist magazine. You can check it out here (I am the first speaker): www.the-scientist.com/exploring-th...
the-scientist.com
Exploring the Gut-Lung Axis in Health and Disease
In this webinar, George O’Toole and Jorge Cervantes will discuss how researchers study the communication between the gut and lung in normal and disease states.
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Reposted by Pauline M.L. Coulon
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 21/07/2025
The Section of Structural and Synthetic Biology at Imperial College is seeking to support candidates for leading their own laboratory through independent fellowship schemes eg Wellcome Trust, MRC Career Development Award, UKRI Future Leaders Fellowships www.imperial.ac.uk/infectious-d...
imperial.ac.uk
Structural and Synthetic Biology
We are interested in understanding molecular mechanisms, especially those that are linked to human disease. We use a multi-disciplinary approach to dissect structures and functions of large macromole...
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Reposted by Pauline M.L. Coulon
Mehrad Hamidian @mehrad-hamidian.bsky.social · 17/07/2025
New paper in Microbial Genomics! Amazing work by @eradah.bsky.social & @liamtobin1.bsky.social & another great collaboration with François Lebreton & Patrick McGann. Here is the link: microbiologyresearch.org/content/jour... #AMR #Acinetobacter @aimi-uts.bsky.social
microbiologyresearch.org
Phylogenomics, evolution and origin of multidrug-resistant Acinetobacter baumannii ST15
We studied the genomic evolution and transmission dynamics of multidrug-resistant ST15 (Institut Pasteur scheme) Acinetobacter baumannii, examining resistance gene acquisition, clonal diversification,...
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Reposted by Pauline M.L. Coulon
Vaughn Cooper @vscooper.micropopbio.org · 16/07/2025
Super proud to be featured in this outstanding video about the risks of and dialogue around mirror bacteria by the amazing @leblob.bsky.social team. I wasn’t confident enough in my French for my interview, merci for the subtitles! youtu.be/DUW-Q-w1FUw?...
youtu.be
Les bactéries miroir vont-elles détruire toute vie sur Terre ? Les scientifiques réagissent
YouTube video by Le Blob
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Reposted by Pauline M.L. Coulon
eLife @elife.bsky.social · 04/07/2025
Modifying gene expression through passive forces 🧬🧪 Passive forces, like where and when mRNA degrades, play a key role in m6A dynamics, without always needing active editing.
buff.ly
Methylation: Modifying gene expression through passive forces
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
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Reposted by Pauline M.L. Coulon
Michael Brockhurst @brockhurstlab.bsky.social · 29/04/2025
This meeting will be great! Abstract submission open now See you 26-27 Nov in Liverpool microbiologysociety.org/event/societ...
microbiologysociety.org
Understanding and predicting microbial evolutionary dynamics - 2025 meeting
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 14/04/2025
Hi everyone, just a quick reminder about @aimi-uts.bsky.social hosting Prof Leo Eberl next week for an @asm-nswact.bsky.social event!
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 14/04/2025
So grateful to have worked with Dr Kirsty Agnoli on this review on colony morphotype variation in #Burkholderia!
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Reposted by Pauline M.L. Coulon
ARC Tracker @arc-tracker.bsky.social · 08/04/2025
I've made my submission to the review of the ARC grant system. Have you? 5 more days, people.
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Reposted by Pauline M.L. Coulon
Stand Up For Science France @standupforscifr.bsky.social · 31/03/2025
Dear colleagues and friends, as the situation continues to deteriorate, we rise to defend academic freedom and stand unwaveringly for science. Now, more than ever, our voices matter. ✊📚🧬 #StandUpForScience Thursday 3rd in France👇 standupforscience.fr/la-journee-d... @standupforscience.bsky.social
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Reposted by Pauline M.L. Coulon
Pauline M.L. Coulon @pmlcoulon.bsky.social · 28/03/2025
Hi everyone! This is official, with the participation of @asm-nswact.bsky.social , @aimi-uts.bsky.social will host Prof Leo Eberl from the Univ of Zurich to talk about the most fascinating bacteria: #Burkholderia Please register for this exciting event!!!!!
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 28/03/2025
Hi everyone! This is official, with the participation of @asm-nswact.bsky.social , @aimi-uts.bsky.social will host Prof Leo Eberl from the Univ of Zurich to talk about the most fascinating bacteria: #Burkholderia Please register for this exciting event!!!!!
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Reposted by Pauline M.L. Coulon
ASM @asm.org · 27/03/2025
The elimination of federal science and health employees is a direct attack on scientific integrity, expertise and public trust. We stand in support of the career public servants who have dedicated their lives’ work to ensuring U.S. health, safety and security: asm.org/Press-Releas...
asm.org
ASM Statement on Major Federal Workforce Cuts
ASM stands in support of the career public servants who have dedicated their lives’ work to ensuring health, safety and security in the United States.
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 27/03/2025
Hi #Burkholderia folks! Got cool B. pseudomallei phenotypes on blood & milk agar during my visit to @Dr Patrick Harris lab (Thanks to @isme-microbes.bsky.social). Any ideas on what’s being secreted? #microbiology
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Reposted by Pauline M.L. Coulon
Scott Delaney @scott-delaney.bsky.social · 24/03/2025
Please please please continue to submit details of your terminated grant using this Google Form 👇 Your submissions continue to be key to understanding patterns of grant terminations and facilitating advocacy and litigation. 💪💪💪
docs.google.com
Cancelled NIH grant information submission form
Please use this form to submit information identifying specific NIH grants that have been cancelled for any reason after January 20, 2025. Data from this form will be used to update the Rescinded NIH...
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Reposted by Pauline M.L. Coulon
Freya Harrison @friendlymicrobe.bsky.social · 20/03/2025
Essential genome of Burkholderia cenocepacia in our cystic fibrosis lung model vs. in waxworm - there are some subtle differences in fitness determinants between these infection models. journals.asm.org/doi/10.1128/... #MicroSky
A PCA plot showing that while many genes are important for fitness in both infections models, some are only necessary in one model.
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 17/03/2025
What a great idea! This scheme is already competitive, asking ECRs to have senior researchers’ track records and they want us to secure employment before accessing the scheme while only 2 years postdoc are available if available… What about ECRs going overseas?
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Reposted by Pauline M.L. Coulon
Torsten Seemann @torstenseemann.bsky.social · 12/03/2025
🚀🧬 MY former colleague @micamer.bsky.social who I worked with in the early years of my career has released a BLAST service (GUI + API options) which replicates the NCBI services but with faster response times.
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Reposted by Pauline M.L. Coulon
The Final Report @firehorse249791.bsky.social · 25/02/2025
[Australia] Flood hit region's disease deaths rise as cyclone looms. 9 dead. au.news.yahoo.com/cyclone-inte... via #ClimateCrisis #GlobalWarming #SevereWeather #Storm #Floods #CycloneAlfred #Disease #Melioidosis #Queensland #Cairns #Australia
au.news.yahoo.com
Flood hit region's disease deaths rise as cyclone looms
The number of deaths from a disease linked with heavy rain has more than doubled in a flood-hit region as authorities track a looming tropical cyclone.
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Reposted by Pauline M.L. Coulon
Dr Sariqa Wagley @sariqawagley.bsky.social · 21/02/2025
Three people die from rare soil-borne disease after flooding in Townsville #Melioidosis www.9news.com.au/national/tow...
9news.com.au
Three people die from rare soil-borne disease after flooding in Townsville
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Reposted by Pauline M.L. Coulon
boppinmule.bsky.social @boppinmule.bsky.social · 25/02/2025
Five more deaths from soil-borne disease melioidosis in Queensland's north 🦠 #melioidosis #queenslandmelioidosis #climatechange #australiadisease www.abc.net.au/news/2025-02...
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Reposted by Pauline M.L. Coulon
ASM @asm.org · 10/03/2025
ASM staff joined the crowd of scientists & citizens who participated in the #standupforscience2025 rally in D.C. (one of many around the world)! While the rallies are over, the need to stand up for science continues. Check out our Action Center for ways to stay involved: asm.org/articles/pol...
Sign that says "Got the plague? Me neither. Thanks science."People holding signs supporting science at a rally.ASM staff at the stand up for science rally in D.C.
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 08/03/2025
Thanks to @Google for coward and silently removing International Women’s day from the calendar! We feel very appreciated… as always! #IWD2025
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 08/03/2025
While bracing for #CycloneAlfred in Brisbane while pushing forward with my #Burkholderia research. I don’t forget my mission Science, not silence! France is rallying for the USA March—what about Australia? Time to #StandUpForScience2025! 🇦🇺🔬
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Reposted by Pauline M.L. Coulon
Michael E. Mann @michaelemann.bsky.social · 07/03/2025
“Out of the lab and into the streets, researchers and doctors rally for science against Trump cuts” by @borenbears.bsky.social for @apnews.com. Read more here: apnews.com/article/scie...
apnews.com
Out of the lab and into the streets, researchers and doctors rally for science against Trump cuts
Researchers, doctors, their patients and supporters are venturing out of labs, hospitals and offices across the country to stand up to what they call an attack on life-saving science by the Trump admi...
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Reposted by Pauline M.L. Coulon
Anonymous @youranoncentral.bsky.social · 07/03/2025
The Stand Up For Science protests have kicked off worldwide. Thousands of scientists demonstrated in solidarity with their US counterparts across France to defend the scientific community. (📹 @Margot_Brunet_) #3E #FranceProtests #USprotests #March7Science #StandUpForScience #Mar7
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 25/02/2025
I highly encourage others to apply! Excited to share that I’ve been awarded this grant to visit @patrickharris laboratory at #auQ starting next week to further my research on #Burkholderia pseudomallei! thanks @isme-microbes.bsky.social
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Reposted by Pauline M.L. Coulon
Jamie Hall @jpjhall.bsky.social · 18/02/2025
I'm delighted to announce that the 2025 @microbiologysociety.org meeting on "Understanding and predicting microbial evolutionary dynamics" will be held in Liverpool 26-27 November 2025! Abstract submission will open soon... #microsky 🧪🧫🦠 microbiologysociety.org/event/societ...
microbiologysociety.org
Understanding and predicting microbial evolutionary dynamics - 2025 meeting
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 17/02/2025
Excited to share this article with the community! Many thanks to @dezieleric.bsky.social for allowing me to start this work during my PhD and for his continued support. I also appreciate @mariecg.bsky.social for her amazing contribution and constant support!
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Eric Déziel @dezieleric.bsky.social · 17/02/2025
New paper out! Phenotypic variation is a feature of several Burkholderia species. We found that quorum sensing and adenosine DNA methylation are two antagonistic systems independently controlling phase variation in B. ambifaria. Great work by @pmlcoulon.bsky.social journals.asm.org/doi/10.1128/...
journals.asm.org
Quorum sensing and DNA methylation play active roles in clinical Burkholderia phase variation | Journal of Bacteriology
Some Burkholderia species are pathogenic to plants, animals, or humans. In immunocompromised individuals, and people suffering from cystic fibrosis, infection from the Burkholderia cepacia complex (Bc...
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Reposted by Pauline M.L. Coulon
Matt Padula @mattpadula.bsky.social · 16/01/2025
Are you an ECR and want to make a positive contribution to the field? Then apply to join Proteomes ECR Editorial Board! You will get to work with me and Jens to ensure our published articles are rigorously and properly reviewed. Details at the link (ignore deadline). www.mdpi.com/about/announ...
mdpi.com
Recruiting Early Career Editorial Board Members for Proteomes
In order to further enhance the international outreach and influence of our journal Proteomes (ISSN: 2227-7382), promote a global academic...
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Reposted by Pauline M.L. Coulon
Australian Institute for Microbiology and Infection @aimi-uts.bsky.social · 05/12/2024
AIMI’s end of year event is underway, with many grants, awards, papers, and other outstanding achievements to celebrate 🎉🥂
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Reposted by Pauline M.L. Coulon
Australian Institute for Microbiology and Infection @aimi-uts.bsky.social · 20/11/2024
Interested in following our researchers and their work? Find them in our starter pack of AIMI researchers! go.bsky.app/QYFfTtT #microsky #microbiology
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Pauline M.L. Coulon @pmlcoulon.bsky.social · 21/11/2024
Here is a starter pack for Burkholderia. Share if you want to be a part of it go.bsky.app/3X6YtvV
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Reposted by Pauline M.L. Coulon
Matt Barber @biobarber.bsky.social · 17/11/2024
Excited to see many in the bacterial pathogenesis community joining here in the last few weeks, so here's a Starter Pack to help make connections. Reply/DM to be added to this or future Packs. #Microsky go.bsky.app/VH64BaY
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