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Pépin Lab

@pepinlab.bsky.social
354 followers 132 following 24 posts

Pépin Lab at MGH/Harvard Medical School. Studies ovarian biology, AMH, and women’s health.

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Pépin Lab @pepinlab.bsky.social · 07/08/2026
I’m honored to be speaking at @buckinstitute.org 1st Annual Reproductive Aging Summit on Aug 21 at Buck in Novato for a full day of scientific talks, networking, a community perspectives panel, and a poster session. Hope to see you there! Learn more here: www.buckinstitute.org/events/1st-a...
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Pépin Lab @pepinlab.bsky.social · 23/07/2026
Incredible week at #SSR2026! Proud of the Pépin Lab: 3 talks on AMH biology and women health, a postdoctoral presentation award, and chaired/organized 3 sessions on emerging contraceptive technologies. Excited to see our trainees shine and advance reproductive biology. #MGBresearch
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Pépin Lab @pepinlab.bsky.social · 20/05/2026
🎉 Yesterday was the first meeting of the Boston Area Reproductive Science Network, and what a start! 50+ scientists, 14 institutions, great talks, posters, and exciting conversations that will lead to new collaborations. More events coming, reach out to get involved. #ReproductiveScience
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Daniel MacPhee 🇨🇦 @d-macphee.bsky.social · 13/04/2026
“the team showed that interrupting a key step in meiosis, the process that produces sex cells, can temporarily halt sperm production without causing lasting harm.” #Sperm #Fertility #Contraception 🧪 www.sciencedaily.com/releases/202...
sciencedaily.com
Scientists discover reversible male birth control that stops sperm production
Scientists at Cornell University may be closing in on the long-sought “holy grail” of male contraception: a safe, reversible, nonhormonal method that completely halts sperm production. In a breakthrou...
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Study for the Society of Reproduction @ssrepro.bsky.social · 28/01/2026
Can gene therapy replace surgery? 🐈🔬 Join Philippe Godin & Savannah Speckhart for our 2nd Journal Club! We’re discussing AMH delivery for long-term sterilization in domestic cats. A game-changer for vet med! Register: ssr.org/events/upcoming-events/trai…
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Study for the Society of Reproduction @ssrepro.bsky.social · 29/01/2026
Join us March 6 @ 4 PM for the Roger V. Short Lecture w/ Dr/ David Pépin. We’re discussing AMH breakthroughs in contraception, oncofertility, and feline health. Register: ssr.org/events/upcoming-events/roge…
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Northwestern Center for Reproductive Science @nu-crs.bsky.social · 13/01/2026
CRS Co-Director Dr. Francesca Duncan, and CRS faculty members Dr. Kara Goldman and Dr. Monica Laronda were featured in this New York Times article! Check it out! www.nytimes.com/2025/12/27/h...
nytimes.com
It’s Time to Give the Ovary Some More Respect
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Pépin Lab @pepinlab.bsky.social · 22/09/2025
Well done Josephine! Talk about multitalented…
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Society for Reproductive Biology (Aus/NZ) @reproductionsrb.bsky.social · 04/09/2025
The SRB, SRF and SSR have announced that A/Prof. David Pépin of the Massachusetts General Hospital and Harvard Medical School is the 2025 Recipient of the RV Short Medal and Lecture. A/Prof. Pépin has made significant contributions to understanding the role of AMH in fertility.
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Pépin Lab @pepinlab.bsky.social · 08/08/2025
We're looking for a Postdoctoral Fellow in Machine Learning & Women’s Health in partnership with MIT’s Female Medicine through Machine Learning (FMML fmml.mit.edu ) to build multi-modal ML models related to ovarian aging and its impact on overall health using large, real-world datasets.
massgeneralbrigham.wd1.myworkdayjobs.com
Postdoc Research Fellow Pepin Lab
Site: Massachusetts General Physicians Organization, Inc. Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and syste...
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Michael Hoffman @michaelhoffman.bsky.social · 15/05/2025
This is incredible.
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John Wallingford @jbwallingford.bsky.social · 02/04/2025
Director of the Nat'l Institute of Child Health and Human Development (NICHD) was summarily dismissed yesterday. So here's your reminder that birth defects kill twice as many American kids as cancer. But there is no St. Jude's for birth defects. Only the NICHD. www.nature.com/articles/d41...
nature.com
‘One of the darkest days’: NIH purges agency leadership amid mass layoffs
In shock move, four institute directors at the US biomedical agency are removed from their posts.
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Pépin Lab @pepinlab.bsky.social · 28/03/2025
So proud of our brilliant PhD student Alana Mermin-Bunnell, and thankful for all her work to implement a machine learning follicle counting pipeline.
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Liron Bar-Peled @liron1bar-peled.bsky.social · 26/03/2025
I’m excited to share the latest work from our lab, led by a group of three amazing scientists: Junbing Zhang, Yousuf Ali and Harrison Chong, who describe @nature the discovery of a ROS sensor, VPS35, which links cytosolic H2O2 levels to regulation of mitochondrial translation and
nature.com
Oxidation of retromer complex controls mitochondrial translation - Nature
Systematic base-editing and computational screens identify specific cysteine residues on VPS35 in the retromer complex as key sensors that decrease mitochondrial translation in response to reactive ox...
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STAT @statnews.com · 20/03/2025
Universities aren't doing enough to come to each others' defense, and industry isn't standing up for academia, says @hollylynchez.bsky.social:
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Pépin Lab @pepinlab.bsky.social · 19/03/2025
A great summary on the war against academia and the root of the rising anti-intellectualism open.substack.com/pub/paulwald...
open.substack.com
The Real Goal of Trump's War on Universities
It isn't about stopping antisemitism. It's about power.
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Atul Gawande @agawande.bsky.social · 13/03/2025
Nothing will kill more children than the ongoing decimation of CDC, NIH, and USAID work to lift vaccine uptake in the US and world. Child survival rose 75% in the last 50 years. Vaccines account for 40% of that. Measles vax alone was 60% of the benefit. www.thelancet.com/journals/lan...
thelancet.com
Contribution of vaccination to improved survival and health: modelling 50 years of the Expanded Programme on Immunization
Since 1974 substantial gains in childhood survival have occurred in every global region. We estimate that EPI has provided the single greatest contribution to improved infant survival over the past 50...
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 13/03/2025
The House of Representatives just passed a CR that includes devastating cuts to the Congressionally Directed Medical Research Program (CDMRP) – 57% cut. It is absolutely critical that we reach out to our Senators now and urge them NOT to include these cuts. Call them!
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Pépin Lab @pepinlab.bsky.social · 11/03/2025
This is a useful resource if you’re trying to keep track of NIH study section meetings, a google doc kept up to date by Dr Barber. docs.google.com/spreadsheets...
docs.google.com
2025 Study section tracking
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Pépin Lab @pepinlab.bsky.social · 07/03/2025
You know it’s bad when the scientists go outside.
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Pépin Lab @pepinlab.bsky.social · 05/03/2025
For those in the Boston area, the stand up for science demonstration will be at the capitol this Friday 3/7 12-4. i0.wp.com/standupforsc...
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Jeremy Berg @jeremymberg.bsky.social · 02/03/2025
I am not going to call this a Bluetorial, because I do not want to sully that term (which, at least I, find joyful). Let’s call it a Orwellial.
media.tenor.com
a cartoon of homer simpson holding a card
ALT: a cartoon of homer simpson holding a card
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Pépin Lab @pepinlab.bsky.social · 27/02/2025
Senior investigators are now on the chopping block. We could all suffer the same fate if we can’t unite to stop the willful dismantling of scientific research. www.science.org/content/arti...
science.org
NIH ban on renewing senior scientists adds to assaults on its in-house research
Policy follows firings of tenure-track scientists and suspension of training programs
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Itai Yanai @itaiyanai.bsky.social · 26/02/2025
If you are worried about science there IS something that you can do! Join us next Friday in DC to make your voice heard. Come and stand up for science! Show that science is for everyone. I’ll be there and I can’t wait to see you there too! @standupforscience.bsky.social
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David Hackney @davidnhackney.bsky.social · 21/02/2025
Medical research funding is usually both public (NIH) and private (pharma), i.e. the TV drug ads Preterm birth & preeclampsia research is almost entirely non-industry Most pharmaceutical companies avoid pregnant patients like the plague. So freezing NIH essentially freezes our field #MedSky
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Elisa Zhang, Ph.D. @elisazhang.bsky.social · 16/02/2025
Get ready to #standupforscience in 2.5 weeks!
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STAT @statnews.com · 10/02/2025
#BREAKING - 22 states sue to block Trump administration cuts to NIH research payments
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22 states sue to block Trump administration cuts to NIH research payments
Attorneys general sued the Trump administration to block a NIH decision that would slash grant payments for research overhead
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STAT @statnews.com · 08/02/2025
#BREAKING - NIH plans to slash support for indirect research costs, sending shockwaves through science
buff.ly
NIH plans to slash support for indirect research costs, sending shockwaves through science
The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%
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Ronny Drapkin @rdrapkin8-penn.bsky.social · 24/01/2025
The Ovarian Cancer Research Syndicate schedule is out from the @pennmedicine.bsky.social Ovarian Cancer Research Center. Great line up!
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Pépin Lab @pepinlab.bsky.social · 09/01/2025
Congrats to Dr Godin who did a great job presenting our work on cat contraception at #Fertility2025. We’ve shown that we can treat kittens with AMH gene therapy before puberty and they will be contracepted at maturity with no adverse effects on hormones! Finally, a non-surgical alternative for pets.
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Pépin Lab @pepinlab.bsky.social · 14/12/2024
Preprint alert 🚨 www.biorxiv.org/content/10.1... . I’m pleased to tease this story regarding FSTL3 as a potential biomarker and therapeutic target in #ovariancancer. A thread 🧵1/n .
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Catherine Rampell @crampell.bsky.social · 01/12/2024
Research supported by NIH has led more than 100 Nobel Prizes and has supported more than 99% of drugs approved by federal regulators from 2010 to 2019. But come January, NIH may face a wrecking ball nytimes.com/2024/12/01/h...
nytimes.com
Long a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target
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Çağrı Çevrim @cagricevrim.bsky.social · 15/11/2024
✨ I’ve finally gathered enough amazing researchers to create a BlueSky starter pack for those studying the female reproductive tract! Please follow, share widely, and (self-)nominate anyone who should be included. Let’s grow this community together! ✨ 🧪 go.bsky.app/FyubCiJ
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Pépin Lab @pepinlab.bsky.social · 26/11/2024
I was digging for decades-old data to put in a new manuscript (proof that useful data never dies) and found this graphic from my first postdoc and good friend Motohiro Kano. Perfect for when family members ask you what you do on Thanksgiving.
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Pépin Lab @pepinlab.bsky.social · 26/11/2024
I’m jealous of the meiosis folks who already self-organized on this platform. I wished there was an #ovarian biology stater pack. So I started to compile one! go.bsky.app/FUTWZ9U
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Itai Yanai @itaiyanai.bsky.social · 25/11/2024
The science version of “what doesn’t kill me makes me stronger”: Scientists with ‘near misses’ early in their careers outperform those with ‘narrow wins’ in the longer run. www.nature.com/articles/s41...
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Pépin Lab @pepinlab.bsky.social · 20/11/2024
We are just starting to understand ovarian aging and its impact on overall health. We are at an inflection point scientifically; new therapeutic paradigms are just around the corner. I just hope that we don’t lose that momentum with the funding dark clouds ahead. www.elle.com/beauty/healt...
elle.com
Could Anti-Aging Your Ovaries Help You Live Longer?
Some promising evidence shows that ovarian health is tied to more than just your fertility.
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