A strategy of engagement with rural partners in the APA-SM trial led to codesign of a feasible, culturally relevant study intervention for use in rural settings. The results were published […]

Pathways to Learning The NIH Pragmatic Trials Collaboratory Learning Path offers an innovative way to learn about designing a pragmatic clinical trial. The interactive, self-paced modules are led by a...

Click on the article title to read more.

Text message reminders to support cardiovascular medication adherence can be a low-cost tool for participating healthcare systems, according to a recent analysis from the Nudge study. The report was p...

The NIH Pragmatic Trials Collaboratory will hold a virtual workshop on September 8 and 9, 2026, on “Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes.” The workshop […]

Using the interactive text messaging intervention from the LungSMART trial as a case study, researchers demonstrated the application of a proposed framework for assessing the fit of custom large langu...

The NIH Pragmatic Trials Collaboratory will hold a virtual workshop on September 8 and 9, 2026, on “Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes.” The workshop […]

STEP-2, an NIH Collaboratory Trial, will evaluate the comparative effectiveness and cost-effectiveness of in-clinic vs mailed distribution of human papillomavirus (HPV) self-sampling kits to improve c...

Members of the NIH Pragmatic Trials Collaboratory’s Electronic Health Records (EHR) Core Working Group recorded the experiences of pragmatic trial investigators in using computable phenotypes in their...

In a secondary analysis of data from the INSPIRE trials, an antibiotic stewardship program that included automated prompts to deliver patient-specific risk information to clinicians led to significant...

In a qualitative study, the APA-SM team gained insights from research partners in rural areas to inform refinements of the trial’s smartphone-based intervention for self-management of chronic musculos...

The NIH Pragmatic Trials Collaboratory will hold a virtual workshop on September 8 and 9, 2026, on “Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes.” The workshop […]

The NIH Office of Disease Prevention will continue its Methods: Mind the Gap webinar series on July 29 with “From Working Models to Reliable Evidence: Robust and Efficient Analysis of […]

Congratulations to Fan Li, associate professor of biostatistics at the Yale School of Public Health, for receiving the Early Career Research Excellence Award from the Association of Schools and Progra...

LungSMART is an NIH Collaboratory Trial testing telehealth interventions designed to address barriers to completing lung cancer screening among patients receiving care in safety net community health c...

APA-SM is an NIH Collaboratory Trial testing a 4-week auricular point acupressure telehealth intervention for self-management of chronic pain in rural communities in South Carolina and Texas. The stud...

CARNATION, an NIH Collaboratory Trial, will test an implementation support intervention designed to enable community health centers to use electronic health records for coordinating primary care–based...

AcademyHealth issued a call for presentations for its 19th Annual Conference on the Science of Dissemination and Implementation (D&I) in Health. The theme of this year’s conference is “Elevating the [...

The planning phase of a pragmatic clinical trial is a critical time when research teams can hone their research questions, build relationships with healthcare system and community partners, and test [...