Sign in

NIH Pragmatic Trials Collaboratory

@pctcollaboratory.bsky.social
148 followers 41 following 117 posts

Supported by NIH, the NIH Pragmatic Trials Collaboratory is advancing the design, conduct, and dissemination of pragmatic clinical trials. Learn more at rethinkingclinicaltrials.org.

PostsRepliesMedia
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 4h
📣 In this week's PCT Grand Rounds, Adrian Hernandez of @dcrinews.bsky.social and @dukemedschool.bsky.social will present “Catalyzing Change: How First-in-Patient Trials Can Fix U.S. Clinical Trials.” Join us! 🔗 du.ke/pctnews20261...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 07/10/2026
📣 In this week's PCT Grand Rounds, Christoph Hornik of @dcrinews.bsky.social and Moulik Shah of Maxis AI will present “An End-to-End Agentic AI Platform to Automate Clinical Trials: A Proof-of-Concept and Evaluation Study.” Join us! 🔗 du.ke/pctnews20261...
010
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 30/09/2026
📣 In this week's PCT Grand Rounds, Diana Higgins and Alicia Heapy of @yaleschoolofmed.bsky.social will present “Self-Directed Versus Clinician-Delivered Cognitive Behavioral Therapy for Chronic Pain: Results From the COPES ExTRA Pragmatic Trial.” Join us! 🔗 du.ke/pctnews20261...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 29/09/2026
Join experienced investigators from the NIH Pragmatic Trials Collaboratory to learn essentials of dissemination and implementation in #pragmatictrials in our full-day workshop at @academyhealth's 19th Annual D&I Conference. #DIScience26 Register today! duke.is/pctnews20260...
Register today - Dissemination and Implementation in Embedded Pragmatic Trials: Tools and Strategies for Enhancing Public Health Impact - A workshop at the 19th Annual Conference on Dissemination and Implementation in Health - National Harbor, MD - December 13, 2026
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 28/09/2026
In NOHARM, an NIH Collaboratory Trial newly published in @jamanetworkopen.com, a strategy to promote nondrug pain care after surgery reduced exposure to opioids without worsening pain interference, physical function, and other patient-reported outcomes. Learn more ➡️ duke.is/pctnews20260...
The graphic shows the title page of the JAMA Network Open article alongside headshots of the NOHARM trial's co–principal investigators, Dr. Andrea Cheville and Dr. Jon Tilburt.
011
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 22/09/2026
📣 Don’t miss the new 4-part podcast series demystifying embedded pragmatic trial design from @pctcollaboratory.bsky.social. Episode 1 sets the stage with NCCIH Director Wendy Weber and NIH Collaboratory co-PIs Adrian Hernandez and Lesley Curtis. 🔗 Listen now: duke.is/pctpod
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 21/09/2026
📣 In this week's PCT Grand Rounds, Corey Bills of @cumedicalschool.bsky.social will discuss the PACT-ARROW study, which uses a master protocol for trials of prevention and treatment of infected traumatic wounds in hospitalized patients in Ukraine. Join us! #pctGR 🔗 duke.is/pctnews20260...
NIH Pragmatic Trials Collaboratory - Rethinking Clinical Trials Grand Rounds - "Research During Active War in Ukraine: Experiences From the PACT-ARROW Study" - Corey Bills, MD, MPH; University of Colorado
011
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 16/09/2026
📣 In this week's PCT Grand Rounds, Erika Rangel of @harvardmed.bsky.social will present “The 4th Trimester Initiative: A Randomized Controlled Trial of Support for Childbearing Medical Trainees.” Join us! 🔗 du.ke/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 09/09/2026
📣 In this week's PCT Grand Rounds, Ryan Zarychanski of @umanitoba.bsky.social will present “Embedded Trials in a Learning Health System: A Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery.” Join us! 🔗 du.ke/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 26/08/2026
📣 In this week's PCT Grand Rounds, Haider Warraich of @arpa-h.bsky.social will present “Evaluating Clinical Agentic AI.” Join us! 🔗 duke.is/pctnews20260...
010
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 25/08/2026
A new article from NOHARM, an NIH Collaboratory Trial, describes strategies and challenges for posttrial sustainment of pragmatic trial interventions. duke.is/pctnews20260...
Headshot of lead author Shrithra Gayathri alongside a screenshot of the article
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 19/08/2026
📣 In this week's PCT Grand Rounds, Eric Karl Oermann of NYU Langone Health and New York University will present “Off-Label Intelligence: Books, Language Models, and AI as a Medical Device.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 18/08/2026
In a new episode of the NIH Collaboratory Podcast, Alison Huang and Derek Angus consider the potential of JAMA+ Trials as a platform and a forum. 🔗 Listen and subscribe: duke.is/pctpod
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 12/08/2026
📣 In this week's PCT Grand Rounds, Christopher Lindsell, Lloyd Michener, @justinbmoorephd.bsky.social, Boris Volkov, and Reuben Adatorwovor will present “Designing for Impact: Introducing Translational Design Studies.” Join us! 🔗 duke.is/pctnews20260...
001
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 05/08/2026
📣 In this week's PCT Grand Rounds, Sreek Vemulapalli of @dukehealth.bsky.social and Ricardo Henao of @duke-university.bsky.social will present “ADAPT-CEC: AI for Clinical Event Adjudication and Implications for Clinical Trials.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 30/07/2026
🎙️ In a new episode of the NIH Collaboratory Podcast, Steven George and Christine Goertz of @dukemedschool.bsky.social discuss slow recruitment mitigation strategies, one of the small group discussion topics at the Steering Committee meeting in April. 🔗 Listen and subscribe: duke.is/pctpod
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 29/07/2026
📣 In this week's PCT Grand Rounds, Steven Z. George and @nickihastings.bsky.social of @dukemedschool.bsky.social will present results and reflections from the AIM-Back cluster randomized clinical trial. Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 27/07/2026
Join us for our 2026 virtual workshop, “Endpoint Strategy in Pragmatic Trials: From Big Questions to Meaningful Outcomes” on September 8 and 9. Registration is free and open to the public. ➡️ Learn more: duke.is/2026-nih-vir... #biostatistics #pragmatictrials #clinicalresearch
A graphic showing the title of the workshop and the topics of the sessions, overlaid on a collage of headshots of the panelists.
001
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 22/07/2026
📣 In this week's PCT Grand Rounds, Rachel Greenberg and Danny Benjamin of @duke-university.bsky.social will present “The Pediatric Trials Network: Innovating to Make Drugs Safe and Effective for Children.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 15/07/2026
📣 In this week's PCT Grand Rounds, Ary Serpa Neto of @monashuniversity.bsky.social and Austin Health will present “Sodium Bicarbonate for Metabolic Acidosis in the Intensive Care Unit.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 08/07/2026
📣 In this week's PCT Grand Rounds, Fran Balamuth of @upenn.edu and Scott Weiss of @jeffersonuniv.bsky.social will present “A Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 01/07/2026
In the OPTIMUM trial, mindfulness-based group telehealth visits led to significant improvements in pain for patients with chronic low back pain. Learn more about the results of this innovative pragmatic clinical trial conducted in real-world primary care settings. duke.is/pctnews20260...
A headshot of Dr. Natalia Morone alongside a screenshot of the title page of the OPTIMUM research article in JAMA Internal Medicine.
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 25/06/2026
🎙️ In a new episode of the NIH Collaboratory Podcast, Brad Hammill and Keith Marsolo of @dukemedschool.bsky.social discuss the challenges and methods associated with the use of death as an endpoint in pragmatic clinical trials. 🔗 Listen and subscribe: duke.is/pctpod
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 24/06/2026
📣 In this week's PCT Grand Rounds, Phillip D. Levy of Wayne State University will present “Precision Engagement to Improve Population Health.” Join us! 🔗 duke.is/ptcnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 16/06/2026
The LungSMART team conducted a bilingual formative evaluation to improve the study’s digital health content for patients in community health centers in Utah. A full pragmatic trial will test strategies to promote lung cancer screening. Learn more ➡️ duke.is/pctnews20260...
Headshot of lead author Andy King alongside an image of the first page of the article from the journal Cancer Control.
010
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 10/06/2026
📣 In this week's PCT Grand Rounds, Jamie Forrest of @science.ubc.ca will present “The REVIVE-TOGETHER Trial: Findings From an Evaluation of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID.” Join us! 🔗 duke.is/pctnews20260...
010
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 03/06/2026
📣 In this week's PCT Grand Rounds, Alison Huang and Derek Angus of JAMA+ Trials will present “Bringing Context and Clarity to Clinical Trial Research for Clinician and Public Health Audiences.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 28/05/2026
🎙️ In a new episode of the NIH Collaboratory Podcast, Roy Perlis of @harvardmed.bsky.social and JAMA+ AI discusses the impact of AI on the scientific publishing industry as well as the opportunities and risks that lie ahead. 🔗 Listen and subscribe: duke.is/pctpod
010
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 27/05/2026
📣 In this week's PCT Grand Rounds, Thomas J. Stopka of @tuftsmedschool.bsky.social will present “Mobile Telemedicine for Treating Chronic Hepatitis C Among Rural People Who Inject Drugs: A Randomized Clinical Trial.” Join us! 🔗 duke.is/ptcnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 20/05/2026
This week, our friends at the NIA IMPACT Collaboratory will host Stephanie Morain of the @bermaninstitute.bsky.social for a Grand Rounds presentation on ePCTs and health systems’ ethical obligations. Join us! 🔗 duke.is/ptcnews20260...
052
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 13/05/2026
📣 In this week's PCT Grand Rounds, Anup Katheria of the Sharp Mary Birch Hospital for Women and Newborns will present “The Importance of Choosing the Right Outcomes: How to Improve Interpretability of Randomized Trials.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 06/05/2026
📣 In this week's PCT Grand Rounds, Charles Scales of @dcrinews.bsky.social and @dukemedschool.bsky.social will present “Prevention of Urinary Stones With Hydration: A Randomized Adherence Trial.” Join us! 🔗 duke.is/pctnews20260...
011
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 29/04/2026
📣 In this week's PCT Grand Rounds, Sebastian Tong and Kushang Patel of @uwnews.uw.edu will present “Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain: Results and Lessons Learned From the Feasibility Phase.” Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 22/04/2026
📣 In this week's PCT Grand Rounds, Jennifer Kawi and Hulin Wu of UTHealth Houston and Jane Bolin of @tamu.bsky.social will present key insights from the APA-SM UG3 trial and the path forward for the UH3. Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 15/04/2026
📣 In this week's PCT Grand Rounds, Roy Perlis of @harvardmed.bsky.social and JAMA+ AI will present "Keeping a Human in the Loop: Scientific Publishing and AI." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 08/04/2026
📣 In this week's PCT Grand Rounds, Julie Lauffenburger of @harvardmed.bsky.social will present "Impact of Behavioral Science-Based Electronic Health Record Tools on Deprescribing for Older Adults." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 01/04/2026
📣 In this week's PCT Grand Rounds, Nestoras Mathioudakis of the @jhu.edu School of Medicine will present "AI for Diabetes Prevention." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 25/03/2026
ICYMI Our recent podcast episode with Dr. David Zaas stressed the need for investment and structural change in healthcare systems to support outstanding, evidence-based clinical care. 🎙️ Listen now: duke.is/pctpodcast20...
Headshot of Dr. David Zaas alongside a quotation: "Too often I think we look at access as a transactional measure. We have to build systems where we deliver the same outstanding quality and excellence at every site, which means specialization and access to clinical trials as part of a standard of care."
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 25/03/2026
📣 In this week's PCT Grand Rounds, Sarah L. Cutrona of @umasschan.bsky.social will present "Text Messaging and Video Stories to Support Hypertension Self-Management in Black Veterans: A Randomized Clinical Trial." Join us! 🔗 duke.is/pctnews20260...
020
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 18/03/2026
📣 In this week's PCT Grand Rounds, Lauralyn McIntyre and Monica Taljaard of @uottawa.ca will present "FLUID: A Cross-Over Trial of Hospital Wide Ringer’s Lactate vs Normal Saline." Join us! 🔗 duke.is/pctnews20260...
001
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 11/03/2026
📣 In this week's PCT Grand Rounds, @drdodson.bsky.social of @nyulangone.bsky.social will present "Behavioral Economics and Medication Adherence for Hypertension: A Randomized Clinical Trial." Join us! 🔗 duke.is/pctnews20260...
020
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 04/03/2026
📣 In this week's PCT Grand Rounds, Christopher C. Butler of @ox.ac.uk will share lessons learned and developments from large-scale European adaptive platform trials of therapeutics for acute respiratory infections. Join us! 🔗 duke.is/pctnews20260...
111
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 25/02/2026
📣 In this week's PCT Grand Rounds, Panos Kougias and Sherene Sharath of SUNY Downstate Health Sciences University will present "Optimal Transfusion Strategy in High Cardiac Risk Patients After Major Surgery: Results of the TOP Trial." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 24/02/2026
The latest article from our Implementation Science Core presents the results of a survey about the measurement of implementation outcomes in pragmatic clinical trials. #impsci #implementationscience Learn more ➡️ duke.is/pctnews20260...
A headshot of first author Katy Trinkley alongside the cover image of the journal Implementation Science Communications.
011
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 18/02/2026
📣 In this week's PCT Grand Rounds, Diana Burgess and Roni Evans of the University of Minnesota as well as Katie Hadlandsmyth of the University of Iowa will present early progress and lessons learned from the RAMP trial. Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 11/02/2026
📣 In this week's PCT Grand Rounds, Michael D. Kappelman of the University of North Carolina at Chapel Hill will present "The Making of the PCORnet® COMPARE-Pediatric IBD Study." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 04/02/2026
📣 In this week's PCT Grand Rounds, Gert Bronfort and Brent Leininger of the University of Minnesota will present "Spinal Manipulation and Clinician-Supported Biopsychosocial Self-Management for Acute Back Pain: The PACBACK Randomized Clinical Trial." Join us! 🔗 duke.is/pctnews20260...
000
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 29/01/2026
Early bird registration for HCSRN’s 2026 Annual Conference in Dallas will end on March 2. Register today to secure the discounted pricing. The theme of this year's conference is "Scaling Learning Health Systems: Data Driven Pathways to Better Outcomes." duke.is/pctnews20260... #HCSRN2026
The logo for the 2026 HCSRN Annual Conference superimposed on a photo of the Dallas skyline at night.
001
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 28/01/2026
📣 In this week's PCT Grand Rounds, @majeans2011.bsky.social and Mary Ryan Baumann of @uwmadison.bsky.social will present "A Pragmatic Randomized Controlled Trial of Ambient Artificial Intelligence to Improve Health Practitioner Well-Being." Join us! 🔗 duke.is/pctnews20260...
024
NIH Pragmatic Trials Collaboratory @pctcollaboratory.bsky.social · 27/01/2026
Complete materials are now available from our recent workshop at @academyhealth.bsky.social's #DIScience25 conference: "Dissemination and Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions." ➡️ duke.is/pctnews20260...
Workshop materials now available - Dissemination and Implementation in Embedded Pragmatic Trials: Science-Powered Strategies to Sustain and Spread Effective Interventions" - A workshop at the 18th Annual Conference on the Science of Dissemination and Implementation in Health
001